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Q94688 (ALDH9_POLMI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Aldehyde dehydrogenase 9

EC=1.2.1.3
Alternative name(s):
PM-ALDH9
Gene names
Name:ALDH9
OrganismPolyandrocarpa misakiensis (Tunicate)
Taxonomic identifier7723 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaePolyandrocarpa

Protein attributes

Sequence length228 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An aldehyde + NAD+ + H2O = a carboxylate + NADH.

Pathway

Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processethanol catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionaldehyde dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›228›228Aldehyde dehydrogenase 9
PRO_0000056431

Regions

Nucleotide binding76 – 816NAD By similarity

Sites

Active site991 Potential
Active site1321 Potential

Experimental info

Non-terminal residue11
Non-terminal residue2281

Sequences

Sequence LengthMass (Da)Tools
Q94688 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 8EF9C3084AB1CB88

FASTA22824,460
        10         20         30         40         50         60 
FPLLMQAWKL GPALACGNTV VMKTAEQTPL TALYVAALAK EAGFPPGVIN IISGYGPTAG 

        70         80         90        100        110        120 
AAISEHMDVD KVAFTGSTET AHIVMEAAAK SNLKRVSLEL GGKSPMIVLA DSDLDFAVDT 

       130        140        150        160        170        180 
CHHGLFFNMG QCCCAGSRIY VQEGVYDEFV KKSVERAKKR TVGDPFTEGI EQGPQIDTEQ 

       190        200        210        220 
FNKINRMIEE GKQSGAKLLC GGKRWGDKGY YIEPTVFSDV PDDSTIGS 

« Hide

References

[1]"Molecular cloning and expression of aldehyde dehydrogenases in the budding ascidian Polyandrocarpa misakiensis."
Harafuji N., Miyashita S., Kawamura K., Fujiwara S.
Mem. Fac. Sci. Kochi Univ. D Biol. 16:7-16(1996)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Ushimado.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D88309 Genomic DNA. Translation: BAA13586.1.

3D structure databases

ProteinModelPortalQ94688.
SMRQ94688. Positions 1-227.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOVERGENHBG000097.

Enzyme and pathway databases

UniPathwayUPA00780; UER00768.

Family and domain databases

Gene3D3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
[Graphical view]
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. SSF53720. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALDH9_POLMI
AccessionPrimary (citable) accession number: Q94688
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: October 16, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways