Q94688 (ALDH9_POLMI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Aldehyde dehydrogenase 9
EC=1.2.1.3

Alternative name(s):
PM-ALDH9

Gene names

Name:

ALDH9

Organism

Polyandrocarpa misakiensis (Tunicate)

Taxonomic identifier

7723 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Urochordata › Ascidiacea › Stolidobranchia › Styelidae › Polyandrocarpa

Protein attributes

Sequence length	228 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An aldehyde + NAD+ + H2O = a carboxylate + NADH.
Pathway	Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
Sequence similarities	Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
Molecular function	aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›228	›228	Aldehyde dehydrogenase 9		PRO_0000056431
Regions
	Nucleotide binding	76 – 81	6	NAD By similarity
Sites
	Active site	99	1	Potential
	Active site	132	1	Potential
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	228	1

Sequences

	Sequence		Length	Mass (Da)
	Q94688 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 8EF9C3084AB1CB88	FASTA	228	24,460
	10 20 30 40 50 60 FPLLMQAWKL GPALACGNTV VMKTAEQTPL TALYVAALAK EAGFPPGVIN IISGYGPTAG 70 80 90 100 110 120 AAISEHMDVD KVAFTGSTET AHIVMEAAAK SNLKRVSLEL GGKSPMIVLA DSDLDFAVDT 130 140 150 160 170 180 CHHGLFFNMG QCCCAGSRIY VQEGVYDEFV KKSVERAKKR TVGDPFTEGI EQGPQIDTEQ 190 200 210 220 FNKINRMIEE GKQSGAKLLC GGKRWGDKGY YIEPTVFSDV PDDSTIGS

References

[1]	"Molecular cloning and expression of aldehyde dehydrogenases in the budding ascidian Polyandrocarpa misakiensis." Harafuji N., Miyashita S., Kawamura K., Fujiwara S. Mem. Fac. Sci. Kochi Univ. D Biol. 16:7-16(1996) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Ushimado.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D88309 Genomic DNA. Translation: BAA13586.1.
3D structure databases
ProteinModelPortal	Q94688.
SMR	Q94688. Positions 1-227.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG000097.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALDH9_POLMI

Accession

Primary (citable) accession number: Q94688

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program