Reviewed, UniProtKB/Swiss-Prot Q94688 (ALDH9_POLMI)

Names and origin

Protein names

Recommended name:
    Aldehyde dehydrogenase 9
    EC=1.2.1.3
Alternative name(s):
    PM-ALDH9

Gene names

Name:

ALDH9

Organism

Polyandrocarpa misakiensis

Taxonomic identifier

7723 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Urochordata › Ascidiacea › Stolidobranchia › Styelidae › Polyandrocarpa

Protein attributes

Sequence length	228 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	An aldehyde + NAD(+) + H(2)O = an acid + NADH.
Pathway	Alcohol metabolism; ethanol degradation; acetate from ethanol: step 2/2.
Sequence similarities	Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aldehyde dehydrogenase (NAD) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›228	›228	Aldehyde dehydrogenase 9		PRO_0000056431
Regions
	Nucleotide binding	76 – 81	6	NAD By similarity
Sites
	Active site	99	1	Potential
	Active site	132	1	Potential
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	228	1

Sequences

	Sequence		Length	Mass (Da)
	Q94688-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 8EF9C3084AB1CB88	FASTA	228	24,460
	10 20 30 40 50 60 FPLLMQAWKL GPALACGNTV VMKTAEQTPL TALYVAALAK EAGFPPGVIN IISGYGPTAG 70 80 90 100 110 120 AAISEHMDVD KVAFTGSTET AHIVMEAAAK SNLKRVSLEL GGKSPMIVLA DSDLDFAVDT 130 140 150 160 170 180 CHHGLFFNMG QCCCAGSRIY VQEGVYDEFV KKSVERAKKR TVGDPFTEGI EQGPQIDTEQ 190 200 210 220 FNKINRMIEE GKQSGAKLLC GGKRWGDKGY YIEPTVFSDV PDDSTIGS

References

[1]	"Molecular cloning and expression of aldehyde dehydrogenases in the budding ascidian Polyandrocarpa misakiensis." Harafuji N., Miyashita S., Kawamura K., Fujiwara S. Mem. Fac. Sci. Kochi Univ. D Biol. 16:7-16(1996) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Ushimado.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D88309 Genomic DNA. Translation: BAA13586.1.
3D structure databases
HSSP	HSSP built from PDB template 1O04 based on UniProtKB P05091.
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q94688.
Family and domain databases
InterPro	IPR016160. Ald_DHase_CS. IPR016162. Ald_DHase_N. IPR015590. Aldehyde_DHase. [Graphical view]
Gene3D	G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHER	PTHR11699. Aldehyde_dehyd. 1 hit.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ALDH9_POLMI

Accession

Primary (citable) accession number: Q94688

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	November 4, 2008
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)