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Q94497 (SELD_DICDI) Reviewed, UniProtKB/Swiss-Prot

Last modified November 16, 2011. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Selenide, water dikinase

EC=2.7.9.3
Alternative name(s):
Selenium donor protein
Selenophosphate synthase
Gene names
Name:selD
ORF Names:DDB_G0282367
OrganismDictyostelium discoideum (Slime mold)
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium

Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Synthesizes selenophosphate from selenide and ATP.

Catalytic activity

ATP + selenide + H2O = AMP + selenophosphate + phosphate.

Sequence similarities

Belongs to the selenophosphate synthase 1 family. Class II subfamily.

Ontologies

Keywords
   Coding sequence diversitySelenocysteine
   LigandATP-binding
Nucleotide-binding
Selenium
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processselenocysteine metabolic process

Inferred from direct assay. Source: dictyBase

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

selenide, water dikinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 364364Selenide, water dikinase
PRO_0000127655

Regions

Nucleotide binding247 – 2537ATP Potential

Sites

Active site251 Potential
Site281Important for catalytic activity

Amino acid modifications

Non-standard residue251Selenocysteine Probable

Experimental info

Sequence conflict251U → G in AAB17998. Ref.2
Sequence conflict431E → G in AAB17998. Ref.2
Sequence conflict661D → DVSLKLFKNKNKLIKLYIYI YLIYIYIFFIIFLKKK in AAB17998. Ref.2
Sequence conflict1241I → K in AAB17998. Ref.2
Sequence conflict1801K → N in AAB17998. Ref.2
Sequence conflict1861V → F in AAB17998. Ref.2
Sequence conflict198 – 2003ERW → KRG in AAB17998. Ref.2
Sequence conflict2101E → K in AAB17998. Ref.2
Sequence conflict2251R → K in AAB17998. Ref.2
Sequence conflict2321R → K in AAB17998. Ref.2
Sequence conflict2361K → N in AAB17998. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q94497 [UniParc].

Last modified February 26, 2008. Version 3.
Checksum: 09DD8AA7105A8615

FASTA36440,552
        10         20         30         40         50         60 
MSISIKDKKE ELLCRLTDFT KLKGUGCKVP QAELLSLLDG IGEGIGYDCS ISQTKFPDIV 

        70         80         90        100        110        120 
MIQTTDFFFP LVDDPYFQGK IACANVLSDL YSFGIEDCDN MLMLLACSTD MTAEQRQWSS 

       130        140        150        160        170        180 
KLMIQGFNDQ AICAGSKVSG GQTVKNPWPI VGGVATSILK TNEFIKPVNA VPGDVLVLTK 

       190        200        210        220        230        240 
PLGTQVCVNF HQWLSKPERW EKINTITNAE ECEQVFNYAT LSMARLNRVG ARLMKKYNAH 

       250        260        270        280        290        300 
AATDVTGFGI LGHSTNLAQN QLLPIRFEIH TLPIIKHMKK LEDHLNHPFK LLKGTSAETS 

       310        320        330        340        350        360 
GGLLISMSRE NAEAFCKEIY EIEKQPAWII GDVIDQSSNY DRSKNTSIIL ENPKIIEVEP 


NTNF 

« Hide

References

« Hide 'large scale' references
[1]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed: 15875012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.
[2]"The selD gene of Dictyostelium."
Shaulsky G., Loomis W.F.
Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-335.
Strain: AX4.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAFI02000047 Genomic DNA. Translation: EAL66043.2.
U68248 mRNA. Translation: AAB17998.1.
RefSeqXP_640038.2. XM_634946.2.

3D structure databases

ProteinModelPortalQ94497.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ94497.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsDDB0214887; DDB0214887; DDB_G0282367.
GeneID8623564.
GenomeReviewsGene locus selD in contig CM000152_GR.
KEGGddi:DDB_G0282367.

Organism-specific databases

dictyBaseDDB_G0282367. selD.

Phylogenomic databases

eggNOGKOG3939.
HOGENOMHBG383791.
OMAGMDSCVI.
ProtClustDBCLSZ2430450.

Family and domain databases

InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR016188. PurM_N-like.
IPR004536. SelD.
[Graphical view]
KOK01008.
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
PIRSFPIRSF036407. Selenphspht_syn. 1 hit.
SUPFAMSSF56042. AIR_synth_C. 1 hit.
SSF55326. PurM_N-like. 1 hit.
TIGRFAMsTIGR00476. SelD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSELD_DICDI
AccessionPrimary (citable) accession number: Q94497
Secondary accession number(s): Q54SK1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: February 26, 2008
Last modified: November 16, 2011
This is version 67 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

SIMILARITY comments

Index of protein domains and families