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Protein

Laccase-3

Gene

LAC3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi82 – 821Copper 1By similarity
Metal bindingi84 – 841Copper 2By similarity
Metal bindingi127 – 1271Copper 2By similarity
Metal bindingi129 – 1291Copper 3By similarity
Metal bindingi468 – 4681Copper 4By similarity
Metal bindingi471 – 4711Copper 1By similarity
Metal bindingi473 – 4731Copper 3By similarity
Metal bindingi530 – 5301Copper 3By similarity
Metal bindingi531 – 5311Copper 4By similarity
Metal bindingi532 – 5321Copper 2By similarity
Metal bindingi536 – 5361Copper 4By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-3 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 3
Diphenol oxidase 3
Urishiol oxidase 3
Gene namesi
Name:LAC3
Ordered Locus Names:Os01g0827300, LOC_Os01g61160
ORF Names:B1088C09.5
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 1

Organism-specific databases

GrameneiQ941X2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 567543Laccase-3PRO_0000291888Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi78 – 781N-linked (GlcNAc...)Sequence Analysis
Glycosylationi148 – 1481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi187 – 1871N-linked (GlcNAc...)Sequence Analysis
Glycosylationi203 – 2031N-linked (GlcNAc...)Sequence Analysis
Glycosylationi298 – 2981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi330 – 3301N-linked (GlcNAc...)Sequence Analysis
Glycosylationi379 – 3791N-linked (GlcNAc...)Sequence Analysis
Glycosylationi389 – 3891N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Expressioni

Gene expression databases

ExpressionAtlasiQ941X2. baseline.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g61160.1.

Structurei

3D structure databases

ProteinModelPortaliQ941X2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 148117Plastocyanin-like 1Add
BLAST
Domaini158 – 310153Plastocyanin-like 2Add
BLAST
Domaini415 – 551137Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ941X2.
KOiK05909.
OMAiQHRMTVV.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q941X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSSSRLL FLLSCSVLAL LAGAEVHHHE FIVQETPVKR LCKTHNVITV
60 70 80 90 100
NGQLPGPTLE VREGDTVVIN VVNHAQYNVT IHWHGIRQFR TGWADGPEFV
110 120 130 140 150
TQCPIKPGGS YKYRFTIEGQ EGTLWWHAHS SWLRATVYGA LIIRPRENKT
160 170 180 190 200
YPFEKPAREV PLILGEWWDA DPIQVIREAQ RTGAAPNISD AYTINGQPGD
210 220 230 240 250
LYNCSKEETT AVPVKPGETA LLRFINAALN QELFVSIAQH KMTVVGVDAS
260 270 280 290 300
YTKPFTTSVL MIAPGQTTDV LVTMDQAPTR YYLAARAYDS AQGVAFDNTT
310 320 330 340 350
TTAVIEYDCG CATDFGPSIP PAFPVLPAFN DTNTATAFAA GIRSPHEVKI
360 370 380 390 400
PGPVDENLFF TVGVGLFNCE PGQQCGGPNN TRFTASMNNI SFVFPQTTSL
410 420 430 440 450
LHAHYYGIPG VFTTDFPAYP PVQFDYTAQN VPRYLWQPVP ATKLYKLKFG
460 470 480 490 500
SVVQIVLQDT SIVSPENHPI HIHGYDFYIL AEGFGNFDPK KDAKKFNYVD
510 520 530 540 550
PPQRNTVAVP TNGWAVIRFV ADNPGVWLMH CHLDVHITWG LAMAFLVEDG
560
YGKLETLEAP PVDLPMC
Length:567
Mass (Da):62,646
Last modified:December 1, 2001 - v1
Checksum:iFA8603416C584361
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003734 Genomic DNA. Translation: BAB68098.1.
AP008207 Genomic DNA. Translation: BAF06593.1.
AK071929 mRNA. No translation available.
RefSeqiNP_001044679.1. NM_001051214.1.
UniGeneiOs.34310.

Genome annotation databases

EnsemblPlantsiOS01T0827300-01; OS01T0827300-01; OS01G0827300.
GeneIDi4327522.
KEGGiosa:4327522.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003734 Genomic DNA. Translation: BAB68098.1.
AP008207 Genomic DNA. Translation: BAF06593.1.
AK071929 mRNA. No translation available.
RefSeqiNP_001044679.1. NM_001051214.1.
UniGeneiOs.34310.

3D structure databases

ProteinModelPortaliQ941X2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g61160.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0827300-01; OS01T0827300-01; OS01G0827300.
GeneIDi4327522.
KEGGiosa:4327522.

Organism-specific databases

GrameneiQ941X2.

Phylogenomic databases

eggNOGiCOG2132.
HOGENOMiHOG000241916.
InParanoidiQ941X2.
KOiK05909.
OMAiQHRMTVV.

Gene expression databases

ExpressionAtlasiQ941X2. baseline.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence and structure of rice chromosome 1."
    Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.
    , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
    Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC3_ORYSJ
AccessioniPrimary (citable) accession number: Q941X2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 1, 2001
Last modified: July 22, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.