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Protein

Laccase-3

Gene

LAC3

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi82Copper 1By similarity1
Metal bindingi84Copper 2By similarity1
Metal bindingi127Copper 2By similarity1
Metal bindingi129Copper 3By similarity1
Metal bindingi468Copper 4By similarity1
Metal bindingi471Copper 1By similarity1
Metal bindingi473Copper 3By similarity1
Metal bindingi530Copper 3By similarity1
Metal bindingi531Copper 4By similarity1
Metal bindingi532Copper 2By similarity1
Metal bindingi536Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-3 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 3
Diphenol oxidase 3
Urishiol oxidase 3
Gene namesi
Name:LAC3
Ordered Locus Names:Os01g0827300, LOC_Os01g61160
ORF Names:B1088C09.5, OsJ_03932Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_000029188825 – 567Laccase-3Add BLAST543

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi78N-linked (GlcNAc...)Sequence analysis1
Glycosylationi148N-linked (GlcNAc...)Sequence analysis1
Glycosylationi187N-linked (GlcNAc...)Sequence analysis1
Glycosylationi203N-linked (GlcNAc...)Sequence analysis1
Glycosylationi298N-linked (GlcNAc...)Sequence analysis1
Glycosylationi330N-linked (GlcNAc...)Sequence analysis1
Glycosylationi379N-linked (GlcNAc...)Sequence analysis1
Glycosylationi389N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ941X2.

Expressioni

Gene expression databases

GenevisibleiQ941X2. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g61160.1.

Structurei

3D structure databases

ProteinModelPortaliQ941X2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 148Plastocyanin-like 1Add BLAST117
Domaini158 – 310Plastocyanin-like 2Add BLAST153
Domaini415 – 551Plastocyanin-like 3Add BLAST137

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ941X2.
KOiK05909.
OMAiAFNDTSA.
OrthoDBiEOG093605O6.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q941X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSSSRLL FLLSCSVLAL LAGAEVHHHE FIVQETPVKR LCKTHNVITV
60 70 80 90 100
NGQLPGPTLE VREGDTVVIN VVNHAQYNVT IHWHGIRQFR TGWADGPEFV
110 120 130 140 150
TQCPIKPGGS YKYRFTIEGQ EGTLWWHAHS SWLRATVYGA LIIRPRENKT
160 170 180 190 200
YPFEKPAREV PLILGEWWDA DPIQVIREAQ RTGAAPNISD AYTINGQPGD
210 220 230 240 250
LYNCSKEETT AVPVKPGETA LLRFINAALN QELFVSIAQH KMTVVGVDAS
260 270 280 290 300
YTKPFTTSVL MIAPGQTTDV LVTMDQAPTR YYLAARAYDS AQGVAFDNTT
310 320 330 340 350
TTAVIEYDCG CATDFGPSIP PAFPVLPAFN DTNTATAFAA GIRSPHEVKI
360 370 380 390 400
PGPVDENLFF TVGVGLFNCE PGQQCGGPNN TRFTASMNNI SFVFPQTTSL
410 420 430 440 450
LHAHYYGIPG VFTTDFPAYP PVQFDYTAQN VPRYLWQPVP ATKLYKLKFG
460 470 480 490 500
SVVQIVLQDT SIVSPENHPI HIHGYDFYIL AEGFGNFDPK KDAKKFNYVD
510 520 530 540 550
PPQRNTVAVP TNGWAVIRFV ADNPGVWLMH CHLDVHITWG LAMAFLVEDG
560
YGKLETLEAP PVDLPMC
Length:567
Mass (Da):62,646
Last modified:December 1, 2001 - v1
Checksum:iFA8603416C584361
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003734 Genomic DNA. Translation: BAB68098.1.
AP008207 Genomic DNA. Translation: BAF06593.1.
AP014957 Genomic DNA. Translation: BAS75026.1.
CM000138 Genomic DNA. Translation: EEE55611.1.
AK071929 mRNA. Translation: BAG92758.1.
RefSeqiXP_015624567.1. XM_015769081.1.
UniGeneiOs.34310.

Genome annotation databases

EnsemblPlantsiOS01T0827300-01; OS01T0827300-01; OS01G0827300.
GeneIDi4327522.
GrameneiOS01T0827300-01; OS01T0827300-01; OS01G0827300.
KEGGiosa:4327522.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003734 Genomic DNA. Translation: BAB68098.1.
AP008207 Genomic DNA. Translation: BAF06593.1.
AP014957 Genomic DNA. Translation: BAS75026.1.
CM000138 Genomic DNA. Translation: EEE55611.1.
AK071929 mRNA. Translation: BAG92758.1.
RefSeqiXP_015624567.1. XM_015769081.1.
UniGeneiOs.34310.

3D structure databases

ProteinModelPortaliQ941X2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g61160.1.

Proteomic databases

PaxDbiQ941X2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0827300-01; OS01T0827300-01; OS01G0827300.
GeneIDi4327522.
GrameneiOS01T0827300-01; OS01T0827300-01; OS01G0827300.
KEGGiosa:4327522.

Phylogenomic databases

eggNOGiKOG1263. Eukaryota.
COG2132. LUCA.
HOGENOMiHOG000241916.
InParanoidiQ941X2.
KOiK05909.
OMAiAFNDTSA.
OrthoDBiEOG093605O6.

Gene expression databases

GenevisibleiQ941X2. OS.

Family and domain databases

Gene3Di2.60.40.420. 3 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR033138. Cu_oxidase_CS.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLAC3_ORYSJ
AccessioniPrimary (citable) accession number: Q941X2
Secondary accession number(s): B7EK61
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.