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Q941B6 (UBC37_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable ubiquitin-conjugating enzyme E2 37

EC=6.3.2.19
Alternative name(s):
Ubiquitin carrier protein 37
Gene names
Name:UBC37
Ordered Locus Names:At3g24515
ORF Names:MOB24.7
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins By similarity. Ref.1

Catalytic activity

ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.

Pathway

Protein modification; protein ubiquitination.

Sequence similarities

Belongs to the ubiquitin-conjugating enzyme family.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   LigandATP-binding
Nucleotide-binding
   Molecular functionLigase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ubiquitin-protein transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 409409Probable ubiquitin-conjugating enzyme E2 37
PRO_0000345202

Regions

Compositional bias385 – 3884Poly-Glu

Sites

Active site991Glycyl thioester intermediate By similarity

Experimental info

Sequence conflict3981S → L in AAY44876. Ref.1
Sequence conflict3981S → L in AAK96485. Ref.4
Sequence conflict3981S → L in AAL31249. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q941B6 [UniParc].

Last modified May 3, 2011. Version 2.
Checksum: D8E0591E25489ACE

FASTA40945,083
        10         20         30         40         50         60 
MAQAARLSLR MQKELKLLLS DPPHGASFPH LSSAANGSGD FSTFSTIDAQ IEGPEDTVYA 

        70         80         90        100        110        120 
NGIFNLKIQI PERYPFQPPI VSFATPIYHP NIDNSGRICL DILNLPPKGA WQPSLNISTV 

       130        140        150        160        170        180 
LTSMRLLLSE PNPDDGLMCE VSREYKYNRQ TFDYKAREMT EKYAKVKADG CSTSLQIKNH 

       190        200        210        220        230        240 
GDEKSGESGN SVKLKLTVES SLSIAHTVKR ETAGRDEQED GNGKRKAVVG FGEGNSFGND 

       250        260        270        280        290        300 
GIKRSRKKLS LALPSQSQKK DLCGEEELTR GVSAACKENK KPNLNGKKLS LGLKQPCNDT 

       310        320        330        340        350        360 
LASFRTSAAK SDNNRLSRKL SLRSPLGELN EVSKPEVLAQ TDMKLEMNQN EDARSLRGEF 

       370        380        390        400 
ENSVLEETSM AESIVVLDSD DSGQEEEERV SSSRSRLSLA KRRVLKCRP 

« Hide

References

« Hide 'large scale' references
[1]"Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis."
Kraft E., Stone S.L., Ma L., Su N., Gao Y., Lau O.-S., Deng X.-W., Callis J.
Plant Physiol. 139:1597-1611(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, GENE FAMILY, NOMENCLATURE.
[2]"Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones."
Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.
DNA Res. 7:217-221(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.

Web resources

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ027050 mRNA. Translation: AAY44876.1.
AB020746 Genomic DNA. Translation: BAB02001.1.
CP002686 Genomic DNA. Translation: AEE76912.1.
AY052292 mRNA. Translation: AAK96485.1.
AY061922 mRNA. Translation: AAL31249.1.
RefSeqNP_566751.1. NM_113362.1.
UniGeneAt.26504.

3D structure databases

ProteinModelPortalQ941B6.
SMRQ941B6. Positions 10-167.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT3G24515.1-P.

Proteomic databases

PaxDbQ941B6.
PRIDEQ941B6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G24515.1; AT3G24515.1; AT3G24515.
GeneID822045.
KEGGath:AT3G24515.

Organism-specific databases

TAIRAT3G24515.

Phylogenomic databases

eggNOGCOG5078.
HOGENOMHOG000185102.
InParanoidQ9LV54.
KOK13960.
OMASAACKEN.

Enzyme and pathway databases

BioCycARA:AT3G24515-MONOMER.
UniPathwayUPA00143.

Gene expression databases

GenevestigatorQ941B6.

Family and domain databases

Gene3D3.10.110.10. 1 hit.
InterProIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMSSF54495. SSF54495. 1 hit.
PROSITEPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ941B6.

Entry information

Entry nameUBC37_ARATH
AccessionPrimary (citable) accession number: Q941B6
Secondary accession number(s): Q9LV54
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: May 3, 2011
Last modified: May 14, 2014
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names