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Protein

Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial

Gene

AGT2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

L-alanine + glyoxylate = pyruvate + glycine.

Cofactori

GO - Molecular functioni

GO - Biological processi

  • photorespiration Source: UniProtKB-KW
  • response to cadmium ion Source: TAIR

Keywordsi

Molecular functionAminotransferase, Transferase
Biological processPhotorespiration
LigandPyridoxal phosphate

Enzyme and pathway databases

BioCyciARA:AT4G39660-MONOMER
ReactomeiR-ATH-389661 Glyoxylate metabolism and glycine degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial (EC:2.6.1.44)
Alternative name(s):
Beta-alanine-pyruvate aminotransferase 1
Gene namesi
Name:AGT2
Ordered Locus Names:At4g39660
ORF Names:T19P19.50
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G39660
TAIRilocus:2135237 AT4G39660

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 12MitochondrionSequence analysisAdd BLAST12
ChainiPRO_000004194513 – 476Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrialAdd BLAST464

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei320N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PaxDbiQ940M2
PRIDEiQ940M2

Expressioni

Gene expression databases

ExpressionAtlasiQ940M2 baseline and differential
GenevisibleiQ940M2 AT

Interactioni

Subunit structurei

Homotetramer.By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi15400, 1 interactor
STRINGi3702.AT4G39660.1

Structurei

3D structure databases

ProteinModelPortaliQ940M2
SMRiQ940M2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG1404 Eukaryota
COG0160 LUCA
HOGENOMiHOG000020206
InParanoidiQ940M2
KOiK00827
OMAiGMTTQIY
OrthoDBiEOG09360AH6
PhylomeDBiQ940M2

Family and domain databases

CDDicd00610 OAT_like, 1 hit
Gene3Di3.40.640.10, 1 hit
3.90.1150.10, 2 hits
InterProiView protein in InterPro
IPR005814 Aminotrans_3
IPR015424 PyrdxlP-dep_Trfase
IPR015422 PyrdxlP-dep_Trfase_dom1
IPR015421 PyrdxlP-dep_Trfase_major
PfamiView protein in Pfam
PF00202 Aminotran_3, 1 hit
PIRSFiPIRSF000521 Transaminase_4ab_Lys_Orn, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
PROSITEiView protein in PROSITE
PS00600 AA_TRANSFER_CLASS_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q940M2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALQRQLLKR ATSDIYHRRA ISLLRTDFST SPSIADAPPH IPPFVHQPRP
60 70 80 90 100
YKGPSADEVL QKRKKFLGPS LFHYYQKPLN IVEGKMQYLY DESGRRYLDA
110 120 130 140 150
FAGIVTVSCG HCHPDILNAI TEQSKLLQHA TTIYLHHAIG DFAEALAAKM
160 170 180 190 200
PGNLKVVYFV NSGSEANELA MMMARLYTGS LEMISLRNAY HGGSSNTIGL
210 220 230 240 250
TALNTWKYPL PQGEIHHVVN PDPYRGVFGS DGSLYAKDVH DHIEYGTSGK
260 270 280 290 300
VAGFIAETIQ GVGGAVELAP GYLKSVYEIV RNAGGVCIAD EVQTGFGRTG
310 320 330 340 350
SHYWGFQTQD VVPDIVTMAK GIGNGLPLGA VVTTPEIASV LASKILFNTF
360 370 380 390 400
GGNPVCSAGG LAVLNVIDKE KRQEHCAEVG SHLIQRLKDV QKRHDIIGDV
410 420 430 440 450
RGRGLMVGIE LVSDRKDKTP AKAETSVLFE QLRELGILVG KGGLHGNVFR
460 470
IKPPMCFTKD DADFLVDALD YSISRL
Length:476
Mass (Da):51,953
Last modified:December 1, 2001 - v1
Checksum:i9E5ABC10C3C2EC83
GO

Sequence cautioni

The sequence CAA18752 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80629 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti240H → Q in AAD48837 (PubMed:12529529).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF166351 mRNA Translation: AAD48837.1
AL022605 Genomic DNA Translation: CAA18752.1 Sequence problems.
AL161595 Genomic DNA Translation: CAB80629.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE87100.1
AY054264 mRNA Translation: AAL06923.1
BT002306 mRNA Translation: AAN73303.1
PIRiT05003
RefSeqiNP_568064.1, NM_120126.5
UniGeneiAt.22488

Genome annotation databases

EnsemblPlantsiAT4G39660.1; AT4G39660.1; AT4G39660
GeneIDi830120
GrameneiAT4G39660.1; AT4G39660.1; AT4G39660
KEGGiath:AT4G39660

Similar proteinsi

Entry informationi

Entry nameiAGT21_ARATH
AccessioniPrimary (citable) accession number: Q940M2
Secondary accession number(s): Q9SU41, Q9SWE2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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