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Q940K0 (DRL15_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable disease resistance protein At1g61180
Gene names
Ordered Locus Names:At1g61180
ORF Names:F11P17.10
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length889 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable disease resistance protein By similarity.

Domain

The LRR repeats probably act as specificity determinant of pathogen recognition By similarity.

Sequence similarities

Belongs to the disease resistance NB-LRR family.

Contains 5 LRR (leucine-rich) repeats.

Contains 1 NB-ARC domain.

Ontologies

Keywords
   Biological processPlant defense
   Coding sequence diversityAlternative splicing
   DomainCoiled coil
Leucine-rich repeat
Repeat
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdefense response

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionADP binding

Inferred from electronic annotation. Source: InterPro

ATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Alternative products

This entry describes 1 isoform produced by alternative splicing. [Select]

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q940K0-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 889889Probable disease resistance protein At1g61180
PRO_0000212747

Regions

Domain137 – 440304NB-ARC
Repeat512 – 53322LRR 1
Repeat534 – 55522LRR 2
Repeat558 – 58124LRR 3
Repeat582 – 60423LRR 4
Repeat605 – 62723LRR 5
Nucleotide binding179 – 1868ATP Potential
Coiled coil19 – 6446 Potential

Experimental info

Sequence conflict4651G → S in AAK96709. Ref.3

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified April 13, 2004. Version 2.
Checksum: 9156D13EFD56643D

FASTA889101,673
        10         20         30         40         50         60 
MGSCFSLQVS DQTLNRIFNC LIGKSYIRTL EKNLRALQRE MEDLRAIQHE VQNKVARDEA 

        70         80         90        100        110        120 
RHQRRLEAVQ VWLDRVNSVD IECKDLLSVT PVELQKLCLC GLCSKYVCSS YKYGKKVFLL 

       130        140        150        160        170        180 
LEEVKKLNSE GNFDEVSQPP PRSEVEERPT QPTIGQEDML EKAWNRLMED GVGIMGLHGM 

       190        200        210        220        230        240 
GGVGKTTLFK KIHNKFAEIG GTFDIVIWIV VSKGVMISKL QEDIAEKLHL CDDLWKNKNE 

       250        260        270        280        290        300 
SDKATDIHRV LKGKRFVLML DDIWEKVDLE AIGIPYPSEV NKCKVAFTTR SREVCGEMGD 

       310        320        330        340        350        360 
HKPMQVNCLE PEDAWELFKN KVGDNTLSSD PVIVELAREV AQKCRGLPLA LNVIGETMSS 

       370        380        390        400        410        420 
KTMVQEWEHA IHVFNTSAAE FSDMQNKILP ILKYSYDSLG DEHIKSCFLY CALFPEDGEI 

       430        440        450        460        470        480 
YNEKLIDYWI CEGFIGEDQV IKRARNKGYA MLGTLTRANL LTKVGTYYCV MHDVVREMAL 

       490        500        510        520        530        540 
WIASDFGKQK ENFVVQAGVG LHEIPKVKDW GAVRKMSLMD NDIEEITCES KCSELTTLFL 

       550        560        570        580        590        600 
QSNKLKNLPG AFIRYMQKLV VLDLSYNRDF NKLPEQISGL VSLQFLDLSN TSIEHMPIGL 

       610        620        630        640        650        660 
KELKKLTFLD LTYTDRLCSI SGISRLLSLR LLRLLGSKVH GDASVLKELQ QLQNLQELAI 

       670        680        690        700        710        720 
TVSAELISLD QRLAKLISNL CIEGFLQKPF DLSFLASMEN LSSLRVENSY FSEIKCRESE 

       730        740        750        760        770        780 
TESSYLRINP KIPCFTNLSR LEIMKCHSMK DLTWILFAPN LVVLLIEDSR EVGEIINKEK 

       790        800        810        820        830        840 
ATNLTSITPF LKLEWLILYN LPKLESIYWS PLPFPVLLTM DVSNCPKLRK LPLNATSVSK 

       850        860        870        880 
VEEFEIHMYP PPEQENELEW EDDDTKNRFL PSIKPYKYFV YPGMSFLTV

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Web resources

NIB-LRRS

Functional and comparative genomics of disease resistance gene homologs

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AC002294 Genomic DNA. Translation: AAB71477.1.
CP002684 Genomic DNA. Translation: AEE33799.1.
AY054518 mRNA. Translation: AAK96709.1.
IPIIPI00518468.
PIRF96637.
RefSeqNP_176313.1. NM_104799.3.
UniGeneAt.21819.
At.67768.

3D structure databases

ProteinModelPortalQ940K0.
SMRQ940K0. Positions 173-432, 513-634, 814-848.
ModBaseSearch...

Proteomic databases

PaxDbQ940K0.
PRIDEQ940K0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G61180.1; AT1G61180.1; AT1G61180.
GeneID842411.
KEGGath:AT1G61180.

Organism-specific databases

TAIRAt1g61180.

Phylogenomic databases

eggNOGKOG4658.
HOGENOMHOG000238348.
InParanoidQ940K0.
PhylomeDBQ940K0.
ProtClustDBCLSN2681834.

Gene expression databases

ArrayExpressQ940K0.
GenevestigatorQ940K0.

Family and domain databases

InterProIPR000767. Disease_R.
IPR002182. NB-ARC.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF00931. NB-ARC. 1 hit.
[Graphical view]
PRINTSPR00364. DISEASERSIST.
SUPFAMSSF52540. SSF52540. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDRL15_ARATH
AccessionPrimary (citable) accession number: Q940K0
Secondary accession number(s): O22728
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: May 29, 2013
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·Documents