Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperonin CPN60-like 2, mitochondrial

Gene

At3g13860

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

  • protein refolding Source: InterPro
  • response to cadmium ion Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperonin CPN60-like 2, mitochondrial
Alternative name(s):
HSP60-like 2
Gene namesi
Ordered Locus Names:At3g13860
ORF Names:MCP4.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G13860.

Subcellular locationi

GO - Cellular componenti

  • mitochondrion Source: TAIR
  • vacuolar membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 31MitochondrionSequence analysisAdd BLAST31
ChainiPRO_000004579332 – 572Chaperonin CPN60-like 2, mitochondrialAdd BLAST541

Proteomic databases

PaxDbiQ93ZM7.
PRIDEiQ93ZM7.

Expressioni

Gene expression databases

GenevisibleiQ93ZM7. AT.

Interactioni

Protein-protein interaction databases

BioGridi5933. 2 interactors.
IntActiQ93ZM7. 2 interactors.
STRINGi3702.AT3G13860.1.

Structurei

3D structure databases

ProteinModelPortaliQ93ZM7.
SMRiQ93ZM7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG0356. Eukaryota.
COG0459. LUCA.
HOGENOMiHOG000076290.
InParanoidiQ93ZM7.
KOiK04077.
OMAiGGDKQQI.
OrthoDBiEOG093606CJ.
PhylomeDBiQ93ZM7.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q93ZM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRVLSKLSS SIGSSTSRKL VSGRIISSRN YAAKDISFGI GARAAMLQGV
60 70 80 90 100
SEVAEAVKVT MGPKGRNVII ESSYGGPKIT KDGVTVAKSI SFQAKAKNIG
110 120 130 140 150
AELVKQVASA TNKVAGDGTT CATVLTQAIL IEGCKSVAAG VNVMDLRVGI
160 170 180 190 200
NMAIAAVVSD LKSRAVMIST PEEITQVATI SANGEREIGE LIARAMEKVG
210 220 230 240 250
KEGVITVADG NTLDNELEVV EGMKLARGYI SPYFITDEKT QKCELENPII
260 270 280 290 300
LIHEKKISDI NSLLKVLEAA VKSSRPLLIV AEDVESDALA MLILNKHHGG
310 320 330 340 350
LKVCAIKAPG FGDNRKASLD DLAVLTGAEV ISEERGLSLE KIRPELLGTA
360 370 380 390 400
KKVTVTRDDT IILHGGGDKK LIEERCEELR SANEKSTSTF DQEKTQERLS
410 420 430 440 450
KLSGGVAVFK VGGASESEVG ERKDRVTDAL NATRAAVEEG IIPGGGVALL
460 470 480 490 500
YATKALDNLQ TENEDQRRGV QIVQNALKAP AFTIAANAGY DGSLVVGKLL
510 520 530 540 550
EQDDCNFGFD AAKGKYVDMV KAGIIDPVKV IRTALTDAAS VSLLLTTTEA
560 570
SVLVKADENT PNHVPDMASM GM
Length:572
Mass (Da):60,466
Last modified:January 24, 2006 - v2
Checksum:i7CA7CAF188753805
GO

Sequence cautioni

The sequence AAL09728 differs from that shown. Reason: Frameshift at position 419.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti273 – 274SS → KY in AAL09728 (PubMed:14593172).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB028610 Genomic DNA. Translation: BAB02911.1.
CP002686 Genomic DNA. Translation: AEE75427.1.
AY056782 mRNA. Translation: AAL09728.1. Frameshift.
AY094453 mRNA. Translation: AAM19824.1.
BT015923 mRNA. Translation: AAU95459.1.
RefSeqiNP_566466.1. NM_112240.4.
UniGeneiAt.8222.

Genome annotation databases

EnsemblPlantsiAT3G13860.1; AT3G13860.1; AT3G13860.
GeneIDi820599.
GrameneiAT3G13860.1; AT3G13860.1; AT3G13860.
KEGGiath:AT3G13860.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB028610 Genomic DNA. Translation: BAB02911.1.
CP002686 Genomic DNA. Translation: AEE75427.1.
AY056782 mRNA. Translation: AAL09728.1. Frameshift.
AY094453 mRNA. Translation: AAM19824.1.
BT015923 mRNA. Translation: AAU95459.1.
RefSeqiNP_566466.1. NM_112240.4.
UniGeneiAt.8222.

3D structure databases

ProteinModelPortaliQ93ZM7.
SMRiQ93ZM7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi5933. 2 interactors.
IntActiQ93ZM7. 2 interactors.
STRINGi3702.AT3G13860.1.

Proteomic databases

PaxDbiQ93ZM7.
PRIDEiQ93ZM7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G13860.1; AT3G13860.1; AT3G13860.
GeneIDi820599.
GrameneiAT3G13860.1; AT3G13860.1; AT3G13860.
KEGGiath:AT3G13860.

Organism-specific databases

TAIRiAT3G13860.

Phylogenomic databases

eggNOGiKOG0356. Eukaryota.
COG0459. LUCA.
HOGENOMiHOG000076290.
InParanoidiQ93ZM7.
KOiK04077.
OMAiGGDKQQI.
OrthoDBiEOG093606CJ.
PhylomeDBiQ93ZM7.

Miscellaneous databases

PROiQ93ZM7.

Gene expression databases

GenevisibleiQ93ZM7. AT.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiIPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
[Graphical view]
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiPS00296. CHAPERONINS_CPN60. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCH60C_ARATH
AccessioniPrimary (citable) accession number: Q93ZM7
Secondary accession number(s): Q9LRW0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: January 24, 2006
Last modified: November 30, 2016
This is version 100 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.