Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q93YS2

- P2C51_ARATH

UniProt

Q93YS2 - P2C51_ARATH

Protein

Probable protein phosphatase 2C 51

Gene

At3g63340

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 2 (14 Apr 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi117 – 1171Manganese 1By similarity
    Metal bindingi117 – 1171Manganese 2By similarity
    Metal bindingi118 – 1181Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi385 – 3851Manganese 2By similarity
    Metal bindingi436 – 4361Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 51 (EC:3.1.3.16)
    Short name:
    AtPP2C51
    Gene namesi
    Ordered Locus Names:At3g63340
    ORF Names:F16M2.190, MAA21.3
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 3

    Organism-specific databases

    TAIRiAT3G63340.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 528528Probable protein phosphatase 2C 51PRO_0000367975Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriQ93YS2.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT3G63340.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ93YS2.
    SMRiQ93YS2. Positions 135-447.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei8 – 2821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini70 – 438369PP2C-likeAdd
    BLAST

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0631.
    InParanoidiQ93YS2.
    PhylomeDBiQ93YS2.

    Family and domain databases

    Gene3Di3.60.40.10. 3 hits.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    This entry describes 1 isoform i produced by alternative splicing. Align

    Note: A number of isoforms are produced. According to EST sequences.

    Isoform 1 (identifier: Q93YS2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MTSSIKSSLL NLGLLIIFFV FFFLVINCRG ESSTCLAVYK QGGAPAVFQS    50
    PKCPRWILQN WGSPTHSGAG RCHTAAIQGR RNYQEDRLLC ALDLRIPFPG 100
    KTGTPKDVLV GIAAVFDGHN GAEASDMASK LLLDYFALHI NFLLDATFSA 150
    MTRKLIGRFP TKGDHSVILH GVSRDEIMHL YNLDFQMQFR DSLPLHFDDS 200
    LPLDIMKEAL LRAIHDIDVT FTKEASNRKL NSGSTATIAL IADGQLMVAS 250
    IGDSKALLCS EKFETLEEAR ATLVKLYRER RRNRGSSPSR FSDFKLEHGN 300
    GLLRFIAKEL TKDHHPNRED EKIRVEAAGG YVTEWAGVPR VNGQLTVSRA 350
    IGDLTYRSYG VISAPEVMDW QPLVANDSFL VVSSDGIFEK LEVQEVCDLL 400
    WEVNNQTSSG AGVPSYCSIS LADCLVNTAF EKGSMDNMAA VVVPLKSNLV 450
    TQLQRKEQSM NDNKDKIASA LPCSNCTLPL PNDINLGPLQ LKQAQPLGTM 500
    FNRLLRLKTE VFAAFICQRT LLGHLKGK 528
    Length:528
    Mass (Da):58,354
    Last modified:April 14, 2009 - v2
    Checksum:i803DF76D1D45ADE5
    GO

    Sequence cautioni

    The sequence AEE80468.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.
    The sequence AEE80469.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.
    The sequence CAB86435.1 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti199 – 1991D → G in AAL24137. (PubMed:14593172)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL138648 Genomic DNA. Translation: CAB86435.1. Sequence problems.
    CP002686 Genomic DNA. Translation: AEE80468.1. Sequence problems.
    CP002686 Genomic DNA. Translation: AEE80469.1. Sequence problems.
    AY059789 mRNA. Translation: AAL24137.1.
    PIRiT48123.
    UniGeneiAt.26629.

    Genome annotation databases

    EnsemblPlantsiAT3G63340.1; AT3G63340.1; AT3G63340.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL138648 Genomic DNA. Translation: CAB86435.1 . Sequence problems.
    CP002686 Genomic DNA. Translation: AEE80468.1 . Sequence problems.
    CP002686 Genomic DNA. Translation: AEE80469.1 . Sequence problems.
    AY059789 mRNA. Translation: AAL24137.1 .
    PIRi T48123.
    UniGenei At.26629.

    3D structure databases

    ProteinModelPortali Q93YS2.
    SMRi Q93YS2. Positions 135-447.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT3G63340.1-P.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT3G63340.1 ; AT3G63340.1 ; AT3G63340 .

    Organism-specific databases

    TAIRi AT3G63340.

    Phylogenomic databases

    eggNOGi COG0631.
    InParanoidi Q93YS2.
    PhylomeDBi Q93YS2.

    Gene expression databases

    Genevestigatori Q93YS2.

    Family and domain databases

    Gene3Di 3.60.40.10. 3 hits.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
      Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F.
      , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C51_ARATH
    AccessioniPrimary (citable) accession number: Q93YS2
    Secondary accession number(s): F4J0Z1, F4J0Z2, Q9M1V6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: April 14, 2009
    Last modified: October 1, 2014
    This is version 74 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3