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Protein

Probable protein phosphatase 2C 51

Gene

At3g63340

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi117Manganese 1By similarity1
Metal bindingi117Manganese 2By similarity1
Metal bindingi118Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi385Manganese 2By similarity1
Metal bindingi436Manganese 2By similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 51 (EC:3.1.3.16)
Short name:
AtPP2C51
Gene namesi
Ordered Locus Names:At3g63340
ORF Names:F16M2.190, MAA21.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G63340.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679751 – 528Probable protein phosphatase 2C 51Add BLAST528

Expressioni

Gene expression databases

ExpressionAtlasiQ93YS2. baseline and differential.
GenevisibleiQ93YS2. AT.

Structurei

3D structure databases

ProteinModelPortaliQ93YS2.
SMRiQ93YS2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 445PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST375

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ93YS2.
PhylomeDBiQ93YS2.

Family and domain databases

Gene3Di3.60.40.10. 3 hits.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 3 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q93YS2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTSSIKSSLL NLGLLIIFFV FFFLVINCRG ESSTCLAVYK QGGAPAVFQS
60 70 80 90 100
PKCPRWILQN WGSPTHSGAG RCHTAAIQGR RNYQEDRLLC ALDLRIPFPG
110 120 130 140 150
KTGTPKDVLV GIAAVFDGHN GAEASDMASK LLLDYFALHI NFLLDATFSA
160 170 180 190 200
MTRKLIGRFP TKGDHSVILH GVSRDEIMHL YNLDFQMQFR DSLPLHFDDS
210 220 230 240 250
LPLDIMKEAL LRAIHDIDVT FTKEASNRKL NSGSTATIAL IADGQLMVAS
260 270 280 290 300
IGDSKALLCS EKFETLEEAR ATLVKLYRER RRNRGSSPSR FSDFKLEHGN
310 320 330 340 350
GLLRFIAKEL TKDHHPNRED EKIRVEAAGG YVTEWAGVPR VNGQLTVSRA
360 370 380 390 400
IGDLTYRSYG VISAPEVMDW QPLVANDSFL VVSSDGIFEK LEVQEVCDLL
410 420 430 440 450
WEVNNQTSSG AGVPSYCSIS LADCLVNTAF EKGSMDNMAA VVVPLKSNLV
460 470 480 490 500
TQLQRKEQSM NDNKDKIASA LPCSNCTLPL PNDINLGPLQ LKQAQPLGTM
510 520
FNRLLRLKTE VFAAFICQRT LLGHLKGK
Length:528
Mass (Da):58,354
Last modified:April 14, 2009 - v2
Checksum:i803DF76D1D45ADE5
GO

Sequence cautioni

The sequence AEE80468 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.Curated
The sequence AEE80469 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.Curated
The sequence CAB86435 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti199D → G in AAL24137 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA. Translation: CAB86435.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE80468.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE80469.1. Sequence problems.
AY059789 mRNA. Translation: AAL24137.1.
PIRiT48123.
UniGeneiAt.26629.

Genome annotation databases

EnsemblPlantsiAT3G63340.1; AT3G63340.1; AT3G63340.
GrameneiAT3G63340.1; AT3G63340.1; AT3G63340.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA. Translation: CAB86435.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE80468.1. Sequence problems.
CP002686 Genomic DNA. Translation: AEE80469.1. Sequence problems.
AY059789 mRNA. Translation: AAL24137.1.
PIRiT48123.
UniGeneiAt.26629.

3D structure databases

ProteinModelPortaliQ93YS2.
SMRiQ93YS2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G63340.1; AT3G63340.1; AT3G63340.
GrameneiAT3G63340.1; AT3G63340.1; AT3G63340.

Organism-specific databases

TAIRiAT3G63340.

Phylogenomic databases

InParanoidiQ93YS2.
PhylomeDBiQ93YS2.

Miscellaneous databases

PROiQ93YS2.

Gene expression databases

ExpressionAtlasiQ93YS2. baseline and differential.
GenevisibleiQ93YS2. AT.

Family and domain databases

Gene3Di3.60.40.10. 3 hits.
InterProiIPR015655. PP2C.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 3 hits.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP2C51_ARATH
AccessioniPrimary (citable) accession number: Q93YS2
Secondary accession number(s): F4J0Z1, F4J0Z2, Q9M1V6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: November 2, 2016
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.