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Protein

Probable protein phosphatase 2C 51

Gene

At3g63340

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi117Manganese 1By similarity1
Metal bindingi117Manganese 2By similarity1
Metal bindingi118Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi385Manganese 2By similarity1
Metal bindingi436Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 51 (EC:3.1.3.16)
Short name:
AtPP2C51
Gene namesi
Ordered Locus Names:At3g63340
ORF Names:F16M2.190, MAA21.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G63340

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679751 – 528Probable protein phosphatase 2C 51Add BLAST528

Expressioni

Gene expression databases

ExpressionAtlasiQ93YS2 baseline and differential
GenevisibleiQ93YS2 AT

Structurei

3D structure databases

ProteinModelPortaliQ93YS2
SMRiQ93YS2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 445PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST375

Sequence similaritiesi

Belongs to the PP2C family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ93YS2
PhylomeDBiQ93YS2

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 3 hits
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.
Isoform 1 (identifier: Q93YS2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTSSIKSSLL NLGLLIIFFV FFFLVINCRG ESSTCLAVYK QGGAPAVFQS
60 70 80 90 100
PKCPRWILQN WGSPTHSGAG RCHTAAIQGR RNYQEDRLLC ALDLRIPFPG
110 120 130 140 150
KTGTPKDVLV GIAAVFDGHN GAEASDMASK LLLDYFALHI NFLLDATFSA
160 170 180 190 200
MTRKLIGRFP TKGDHSVILH GVSRDEIMHL YNLDFQMQFR DSLPLHFDDS
210 220 230 240 250
LPLDIMKEAL LRAIHDIDVT FTKEASNRKL NSGSTATIAL IADGQLMVAS
260 270 280 290 300
IGDSKALLCS EKFETLEEAR ATLVKLYRER RRNRGSSPSR FSDFKLEHGN
310 320 330 340 350
GLLRFIAKEL TKDHHPNRED EKIRVEAAGG YVTEWAGVPR VNGQLTVSRA
360 370 380 390 400
IGDLTYRSYG VISAPEVMDW QPLVANDSFL VVSSDGIFEK LEVQEVCDLL
410 420 430 440 450
WEVNNQTSSG AGVPSYCSIS LADCLVNTAF EKGSMDNMAA VVVPLKSNLV
460 470 480 490 500
TQLQRKEQSM NDNKDKIASA LPCSNCTLPL PNDINLGPLQ LKQAQPLGTM
510 520
FNRLLRLKTE VFAAFICQRT LLGHLKGK
Length:528
Mass (Da):58,354
Last modified:April 14, 2009 - v2
Checksum:i803DF76D1D45ADE5
GO

Sequence cautioni

The sequence AEE80468 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.Curated
The sequence AEE80469 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.Curated
The sequence CAB86435 differs from that shown. Reason: Erroneous gene model prediction. The predicted gene has been split into 2 genes: At3g63330 and At3g63340.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti199D → G in AAL24137 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA Translation: CAB86435.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE80468.1 Sequence problems.
CP002686 Genomic DNA Translation: AEE80469.1 Sequence problems.
CP002686 Genomic DNA Translation: ANM64224.1
AY059789 mRNA Translation: AAL24137.1
PIRiT48123
RefSeqiNP_001326269.1, NM_001340203.1 [Q93YS2-1]
UniGeneiAt.26629

Genome annotation databases

EnsemblPlantsiAT3G63340.12; AT3G63340.12; AT3G63340 [Q93YS2-1]
GeneIDi825509
GrameneiAT3G63340.12; AT3G63340.12; AT3G63340 [Q93YS2-1]
KEGGiath:AT3G63340

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiP2C51_ARATH
AccessioniPrimary (citable) accession number: Q93YS2
Secondary accession number(s): F4J0Z1, F4J0Z2, Q9M1V6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: April 14, 2009
Last modified: April 25, 2018
This is version 101 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health