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Q93X62

- FABG1_BRANA

UniProt

Q93X62 - FABG1_BRANA

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Protein
3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic
Gene
gbkr1
Organism
Brassica napus (Rape)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei214 – 2141Substrate
Active sitei227 – 2271Proton acceptor

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi82 – 10625NADP By similarity
Add
BLAST

GO - Molecular functioni

  1. 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity Source: UniProtKB-EC
  2. NAD binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. fatty acid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic (EC:1.1.1.100)
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase 1
Beta-keto acyl-carrier protein reductase 1
Gene namesi
Name:gbkr1
OrganismiBrassica napus (Rape)
Taxonomic identifieri3708 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Subcellular locationi

Plastidchloroplast By similarity
Note: And non-photosynthetic plastids By similarity.

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 6060Chloroplast Reviewed prediction
Add
BLAST
Chaini61 – 3202603-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic
PRO_0000031977Add
BLAST

Interactioni

Subunit structurei

Homotetramer.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi79 – 824
Helixi88 – 9912
Beta strandi103 – 1108
Helixi112 – 12514
Beta strandi128 – 1336
Helixi139 – 15214
Beta strandi157 – 1615
Helixi171 – 1733
Helixi176 – 18611
Helixi188 – 20417
Beta strandi207 – 2126
Helixi216 – 2194
Helixi225 – 24622
Turni247 – 2493
Beta strandi250 – 2578
Helixi263 – 2664
Helixi270 – 2778
Helixi288 – 30013
Helixi303 – 3064
Beta strandi311 – 3155
Turni316 – 3194

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1EDOX-ray2.30A77-320[»]
2CDHX-ray4.20G/H/I/J/K/L77-320[»]
ProteinModelPortaliQ93X62.
SMRiQ93X62. Positions 77-320.

Miscellaneous databases

EvolutionaryTraceiQ93X62.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PIRSFiPIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsiTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q93X62-1 [UniParc]FASTAAdd to Basket

« Hide

MATTVAATKL TSLKAVKKLG FREIRQVRQW SPLQSAMPHF GMLRCGSRQS    50
FATSTVVKAQ ATAVEQSTGE AVPKVESPVV VVTGASRGIG KAIALSLGKA 100
GCKVLVNYAR SAKEAEEVSK QIEAYGGQAI TFGGDVSKEA DVEAMMKTAI 150
DAWGTIDVVV NNAGITRDTL LIRMKKSQWD EVIDLNLTGV FLCTQAATKI 200
MMKKRKGRII NIASVVGLIG NIGQANYAAA KAGVIGFSKT AAREGASRNI 250
NVNVVCPGFI ASDMTAKLGE DMEKKILGTI PLGRYGQPED VAGLVEFLAL 300
SPAASYITGQ AFTIDGGIAI 320
Length:320
Mass (Da):33,671
Last modified:December 1, 2001 - v1
Checksum:i3D79CEA41AFFBC49
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ243091 Genomic DNA. Translation: CAC41370.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ243091 Genomic DNA. Translation: CAC41370.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1EDO X-ray 2.30 A 77-320 [» ]
2CDH X-ray 4.20 G/H/I/J/K/L 77-320 [» ]
ProteinModelPortali Q93X62.
SMRi Q93X62. Positions 77-320.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00094 .

Miscellaneous databases

EvolutionaryTracei Q93X62.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR011284. 3oxo_ACP_reduc.
IPR002198. DH_sc/Rdtase_SDR.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PIRSFi PIRSF000126. 11-beta-HSD1. 1 hit.
PRINTSi PR00081. GDHRDH.
PR00080. SDRFAMILY.
TIGRFAMsi TIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. McDonald F.S., White A.J., Elborough K.M., Slabas A.R.
    Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Jet neuf.
    Tissue: Leaf.
  2. "Crystallization of the NADP-dependent beta-keto acyl-carrier protein reductase from Brassica napus."
    Fisher M., Sedelnikova S.E., Martindale W., Thomas N.C., Simon J.W., Slabas A.R., Rafferty J.B.
    Acta Crystallogr. D 56:86-88(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: CRYSTALLIZATION.
  3. "The X-ray structure of Brassica napus beta-keto acyl carrier protein reductase and its implications for substrate binding and catalysis."
    Fisher M., Kroon J.T.M., Martindale W., Stuitje A.R., Slabas A.R., Rafferty J.B.
    Structure 8:339-347(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 77-320.

Entry informationi

Entry nameiFABG1_BRANA
AccessioniPrimary (citable) accession number: Q93X62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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