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Protein

3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic

Gene

gbkr1

Organism
Brassica napus (Rape)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP+ = 3-oxoacyl-[acyl-carrier-protein] + NADPH.

Pathwayi: fatty acid biosynthesis

This protein is involved in the pathway fatty acid biosynthesis, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway fatty acid biosynthesis and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei214Substrate1
Active sitei227Proton acceptor1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi82 – 106NADPBy similarityAdd BLAST25

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

Keywords - Ligandi

NADP

Enzyme and pathway databases

UniPathwayiUPA00094.

Names & Taxonomyi

Protein namesi
Recommended name:
3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic (EC:1.1.1.100)
Alternative name(s):
3-ketoacyl-acyl carrier protein reductase 1
Beta-keto acyl-carrier protein reductase 1
Gene namesi
Name:gbkr1
OrganismiBrassica napus (Rape)
Taxonomic identifieri3708 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 60ChloroplastSequence analysisAdd BLAST60
ChainiPRO_000003197761 – 3203-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplasticAdd BLAST260

Interactioni

Subunit structurei

Homotetramer.

Structurei

Secondary structure

1320
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi79 – 82Combined sources4
Helixi88 – 99Combined sources12
Beta strandi103 – 110Combined sources8
Helixi112 – 125Combined sources14
Beta strandi128 – 133Combined sources6
Helixi139 – 152Combined sources14
Beta strandi157 – 161Combined sources5
Helixi171 – 173Combined sources3
Helixi176 – 186Combined sources11
Helixi188 – 204Combined sources17
Beta strandi207 – 212Combined sources6
Helixi216 – 219Combined sources4
Helixi225 – 246Combined sources22
Turni247 – 249Combined sources3
Beta strandi250 – 257Combined sources8
Helixi263 – 266Combined sources4
Helixi270 – 277Combined sources8
Helixi288 – 300Combined sources13
Helixi303 – 306Combined sources4
Beta strandi311 – 315Combined sources5
Turni316 – 319Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EDOX-ray2.30A77-320[»]
2CDHX-ray4.20G/H/I/J/K/L77-320[»]
ProteinModelPortaliQ93X62.
SMRiQ93X62.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ93X62.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

KOiK00059.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR011284. 3oxo_ACP_reduc.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q93X62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTVAATKL TSLKAVKKLG FREIRQVRQW SPLQSAMPHF GMLRCGSRQS
60 70 80 90 100
FATSTVVKAQ ATAVEQSTGE AVPKVESPVV VVTGASRGIG KAIALSLGKA
110 120 130 140 150
GCKVLVNYAR SAKEAEEVSK QIEAYGGQAI TFGGDVSKEA DVEAMMKTAI
160 170 180 190 200
DAWGTIDVVV NNAGITRDTL LIRMKKSQWD EVIDLNLTGV FLCTQAATKI
210 220 230 240 250
MMKKRKGRII NIASVVGLIG NIGQANYAAA KAGVIGFSKT AAREGASRNI
260 270 280 290 300
NVNVVCPGFI ASDMTAKLGE DMEKKILGTI PLGRYGQPED VAGLVEFLAL
310 320
SPAASYITGQ AFTIDGGIAI
Length:320
Mass (Da):33,671
Last modified:December 1, 2001 - v1
Checksum:i3D79CEA41AFFBC49
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243091 Genomic DNA. Translation: CAC41370.1.
RefSeqiXP_013662543.1. XM_013807089.1.

Genome annotation databases

GeneIDi106367337.
KEGGibna:106367337.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ243091 Genomic DNA. Translation: CAC41370.1.
RefSeqiXP_013662543.1. XM_013807089.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1EDOX-ray2.30A77-320[»]
2CDHX-ray4.20G/H/I/J/K/L77-320[»]
ProteinModelPortaliQ93X62.
SMRiQ93X62.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi106367337.
KEGGibna:106367337.

Phylogenomic databases

KOiK00059.

Enzyme and pathway databases

UniPathwayiUPA00094.

Miscellaneous databases

EvolutionaryTraceiQ93X62.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR011284. 3oxo_ACP_reduc.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR01830. 3oxo_ACP_reduc. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFABG1_BRANA
AccessioniPrimary (citable) accession number: Q93X62
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.