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Q93W25 (Q93W25_WHEAT) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptidyl-prolyl cis-trans isomerase RuleBase RU000493

EC=5.2.1.8 RuleBase RU000493
Gene names
Name:CyP3 EMBL AAK49428.1
Synonyms:CyP1 EMBL AAK49426.1, TaBWCyp A-1 EMBL BAN09078.1
OrganismTriticum aestivum (Wheat) [Complete proteome] EMBL AAK49428.1
Taxonomic identifier4565 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladePooideaeTriticeaeTriticum

Protein attributes

Sequence length171 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides By similarity. RuleBase RU004223

Catalytic activity

Peptidylproline (omega=180) = peptidylproline (omega=0). SAAS SAAS020892 RuleBase RU000493

Sequence similarities

Contains 1 PPIase cyclophilin-type domain. RuleBase RU003420

Contains PPIase cyclophilin-type domain. SAAS SAAS020892

Ontologies

Keywords
   Molecular functionIsomerase
Rotamase SAAS SAAS020892 RuleBase RU003420
   Technical term3D-structure PDB 4HY7 PDB 4E1Q
Complete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytosol

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasma membrane

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionpeptidyl-prolyl cis-trans isomerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q93W25 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 62D45AF2BC55FC6F

FASTA17118,391
        10         20         30         40         50         60 
MANPRVFFDM TVGGAPAGRI VMELYKDAVP RTVENFRALC TGEKGVGKSG KPLHYKGSAF 

        70         80         90        100        110        120 
HRVIPDFMCQ GGDFTRGNGT GGESIYGEKF ADEKFVHKHT KPGILSMANA GPNTNGSQFF 

       130        140        150        160        170 
ICTVPCNWLD GKHVVFGEVV EGMDVVKNIE KVGSRSGTCS KQVVIADCGQ L 

« Hide

References

[1]"Isolation and characterisation of cDNAs encoding protein disulphide isomerases and cyclophilins in wheat."
Johnson J.C., Clarke B.C., Bhave M.
J. Cereal Sci. 34:159-171(2001) [AGRICOLA] [Europe PMC]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Endosperm EMBL AAK49428.1.
[2]"Analysis of the bread wheat genome using whole-genome shotgun sequencing."
Brenchley R., Spannagl M., Pfeifer M., Barker G.L., D'Amore R., Allen A.M., McKenzie N., Kramer M., Kerhornou A., Bolser D., Kay S., Waite D., Trick M., Bancroft I., Gu Y., Huo N., Luo M.C., Sehgal S. expand/collapse author list , Gill B., Kianian S., Anderson O., Kersey P., Dvorak J., McCombie W.R., Hall A., Mayer K.F., Edwards K.J., Bevan M.W., Hall N.
Nature 491:705-710(2012) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"A unique calmodulin binding cyclophilin (TaCyPA-1) from an Indian elite wheat cultivar - Punjab Pread Wheat (PBW-343)."
Singh K., Kaur H., Dutta T., Kumari S., Singla-Pareek S.L., Singh P., Pareek A.
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[4]"cDNA sequences derived from Triticum aestivum cv. Bobwhite."
Haque M.E., Abe F., Mori M., Oyanagi A., Komatsu S., Kawaguchi K.
Submitted (APR-2012) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[5]"Structural and biochemical characterization of the cytosolic wheat cyclophilin TaCypA-1."
Sekhon S.S., Kaur H., Dutta T., Singh K., Kumari S., Kang S., Park S.G., Park B.C., Jeong D.G., Pareek A., Woo E.J., Singh P., Yoon T.S.
Acta Crystallogr. D 69:555-563(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS).
[6]"Separating homeologs by phasing in the tetraploid wheat transcriptome."
Krasileva K.V., Buffalo V., Bailey P., Pearce S., Ayling S., Tabbita F., Soria M., Wang S., Akhunov E., Uauy C., Dubcovsky J.
Genome Biol. 14:R66-R66(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[7]EnsemblPlants
Submitted (JAN-2014) to UniProtKB
Cited for: IDENTIFICATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF262983 Genomic DNA. No translation available.
AF384147 Genomic DNA. No translation available.
AY456122 Genomic DNA. No translation available.
AY456123 Genomic DNA. No translation available.
AY456124 Genomic DNA. No translation available.
EU035525 Genomic DNA. No translation available.
AF262982 mRNA. Translation: AAK49426.1.
AF262984 mRNA. Translation: AAK49428.1.
JQ678695 mRNA. Translation: AFS50133.1.
AB711117 mRNA. Translation: BAN09078.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4E1QX-ray1.25A1-171[»]
4HY7X-ray1.20A1-171[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsTraes_6AS_82E93D872.1; Traes_6AS_82E93D872.1; Traes_6AS_82E93D872.

Family and domain databases

InterProIPR024936. Cyclophilin-type_PPIase.
IPR020892. Cyclophilin-type_PPIase_CS.
IPR002130. Cyclophilin-type_PPIase_dom.
[Graphical view]
PfamPF00160. Pro_isomerase. 1 hit.
[Graphical view]
PIRSFPIRSF001467. Peptidylpro_ismrse. 1 hit.
PRINTSPR00153. CSAPPISMRASE.
PROSITEPS00170. CSA_PPIASE_1. 1 hit.
PS50072. CSA_PPIASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ93W25_WHEAT
AccessionPrimary (citable) accession number: Q93W25
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)