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Protein

Homeobox-leucine zipper protein PROTODERMAL FACTOR 2

Gene

PDF2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probable transcription factor that binds to the L1 box DNA sequence 5'-TAAATG[CT]A-3'. Plays a role in maintaining the identity of L1 cells, possibly by interacting with their L1 box or other target-gene promoters. Functionally redundant to ATML1.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi62 – 121HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

  • DNA binding Source: TAIR
  • DNA binding transcription factor activity Source: TAIR
  • lipid binding Source: InterPro
  • sequence-specific DNA binding Source: InterPro

GO - Biological processi

  • cotyledon development Source: TAIR
  • epidermal cell differentiation Source: TAIR
  • seed germination Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processDifferentiation, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox-leucine zipper protein PROTODERMAL FACTOR 2
Alternative name(s):
HD-ZIP protein PDF2
Homeodomain transcription factor PDF2
Gene namesi
Name:PDF2
Ordered Locus Names:At4g04890
ORF Names:T1J1.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G04890
TAIRilocus:2135368 AT4G04890

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003317351 – 743Homeobox-leucine zipper protein PROTODERMAL FACTOR 2Add BLAST743

Proteomic databases

PaxDbiQ93V99
PRIDEiQ93V99

PTM databases

iPTMnetiQ93V99

Expressioni

Tissue specificityi

Specifically expressed in the layer 1 (L1) of shoot meristems.1 Publication

Gene expression databases

ExpressionAtlasiQ93V99 differential
GenevisibleiQ93V99 AT

Interactioni

Protein-protein interaction databases

BioGridi11139, 8 interactors
IntActiQ93V99, 3 interactors
STRINGi3702.AT4G04890.1

Structurei

3D structure databases

ProteinModelPortaliQ93V99
SMRiQ93V99
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini244 – 476STARTPROSITE-ProRule annotationAdd BLAST233

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili110 – 192Sequence analysisAdd BLAST83

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Homeobox

Phylogenomic databases

eggNOGiENOG410IIN5 Eukaryota
ENOG411107H LUCA
HOGENOMiHOG000243256
InParanoidiQ93V99
KOiK09338
OMAiNFGAQSG
OrthoDBiEOG0936037Q
PhylomeDBiQ93V99

Family and domain databases

CDDicd00086 homeodomain, 1 hit
Gene3Di3.30.530.20, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR023393 START-like_dom_sf
IPR002913 START_lipid-bd_dom
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF01852 START, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SM00234 START, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS50848 START, 1 hit

Sequencei

Sequence statusi: Complete.

Q93V99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYHPNMFESH HMFDMTPKST SDNDLGITGS REDDFETKSG TEVTTENPSG
60 70 80 90 100
EELQDPSQRP NKKKRYHRHT QRQIQELESF FKECPHPDDK QRKELSRDLN
110 120 130 140 150
LEPLQVKFWF QNKRTQMKAQ SERHENQILK SDNDKLRAEN NRYKEALSNA
160 170 180 190 200
TCPNCGGPAA IGEMSFDEQH LRIENARLRE EIDRISAIAA KYVGKPLGSS
210 220 230 240 250
FAPLAIHAPS RSLDLEVGNF GNQTGFVGEM YGTGDILRSV SIPSETDKPI
260 270 280 290 300
IVELAVAAME ELVRMAQTGD PLWLSTDNSV EILNEEEYFR TFPRGIGPKP
310 320 330 340 350
LGLRSEASRQ SAVVIMNHIN LVEILMDVNQ WSCVFSGIVS RALTLEVLST
360 370 380 390 400
GVAGNYNGAL QVMTAEFQVP SPLVPTRENY FVRYCKQHSD GSWAVVDVSL
410 420 430 440 450
DSLRPSTPIL RTRRRPSGCL IQELPNGYSK VTWIEHMEVD DRSVHNMYKP
460 470 480 490 500
LVQSGLAFGA KRWVATLERQ CERLASSMAS NIPGDLSVIT SPEGRKSMLK
510 520 530 540 550
LAERMVMSFC SGVGASTAHA WTTMSTTGSD DVRVMTRKSM DDPGRPPGIV
560 570 580 590 600
LSAATSFWIP VAPKRVFDFL RDENSRKEWD ILSNGGMVQE MAHIANGHEP
610 620 630 640 650
GNCVSLLRVN SGNSSQSNML ILQESCTDAS GSYVIYAPVD IVAMNVVLSG
660 670 680 690 700
GDPDYVALLP SGFAILPDGS VGGGDGNQHQ EMVSTTSSGS CGGSLLTVAF
710 720 730 740
QILVDSVPTA KLSLGSVATV NSLIKCTVER IKAAVSCDVG GGA
Length:743
Mass (Da):81,530
Last modified:December 1, 2001 - v1
Checksum:iDF305491CC69EF8C
GO

Sequence cautioni

The sequence AAD17342 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB81031 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB056455 Genomic DNA Translation: BAB58961.1
AF128393 Genomic DNA Translation: AAD17342.1 Sequence problems.
AL161502 Genomic DNA Translation: CAB81031.1 Different initiation.
CP002687 Genomic DNA Translation: AEE82438.1
CP002687 Genomic DNA Translation: ANM67658.1
AF424560 mRNA Translation: AAL11554.1
AY062575 mRNA Translation: AAL32653.1
BT000144 mRNA Translation: AAN15463.1
PIRiE85061
RefSeqiNP_001329475.1, NM_001340517.1
NP_567274.1, NM_116727.4
UniGeneiAt.4047

Genome annotation databases

EnsemblPlantsiAT4G04890.1; AT4G04890.1; AT4G04890
AT4G04890.2; AT4G04890.2; AT4G04890
GeneIDi825828
GrameneiAT4G04890.1; AT4G04890.1; AT4G04890
AT4G04890.2; AT4G04890.2; AT4G04890
KEGGiath:AT4G04890

Similar proteinsi

Entry informationi

Entry nameiPDF2_ARATH
AccessioniPrimary (citable) accession number: Q93V99
Secondary accession number(s): Q9M0Z0, Q9ZPH7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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