Q93TU6 (Q93TU6_9NOCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
6-oxocamphor hydrolase EMBL AAK50622.1

Gene names

Name:

camK EMBL AAK50622.1

Organism

Rhodococcus sp. NCIMB 9784 EMBL AAK50622.1

Taxonomic identifier

157732 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Hydrolase EMBL AAK50622.1
Technical term	3D-structure PDB 1O8U PDB 1SZO
Gene Ontology (GO)
Molecular function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q93TU6 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 0AE4A9E54CE83EFF	FASTA	257	28,483
	10 20 30 40 50 60 MKQLATPFQE YSQKYENIRL ERDGGVLLVT VHTEGKSLVW TSTAHDELAY CFHDIACDRE 70 80 90 100 110 120 NKVVILTGTG PSFCNEIDFT SFNLGTPHDW DEIIFEGQRL LNNLLSIEVP VIAAVNGPVT 130 140 150 160 170 180 NHPEIPVMSD IVLAAESATF QDGPHFPSGI VPGDGAHVVW PHVLGSNRGR YFLLTGQELD 190 200 210 220 230 240 ARTALDYGAV NEVLSEQELL PRAWELARGI AEKPLLARRY ARKVLTRQLR RVMEADLSLG 250 LAHEALAAID LGMESEQ

References

[1]	"The desymmetrization of bicyclic beta -diketones by an enzymatic retro-Claisen reaction. A new reaction of the crotonase superfamily." Grogan G., Roberts G.A., Bougioukou D., Turner N.J., Flitsch S.L. J. Biol. Chem. 276:12565-12572(2001) [PubMed: 11278926] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIMB 9784 EMBL AAK50622.1.
[2]	"Nucleotide sequence of a portion of the camphor-degrading gene cluster from Rhodococcus sp. NCIMB 9784." Roberts G.A., Grogan G., Turner N.J., Flitsch S.L. DNA Seq. 15:96-103(2004) [PubMed: 15346763] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCIMB 9784 EMBL AAK50622.1.
[3]	"The 2-A crystal structure of 6-oxo camphor hydrolase. New structural diversity in the crotonase superfamily." Whittingham J.L., Turkenburg J.P., Verma C.S., Walsh M.A., Grogan G. J. Biol. Chem. 278:1744-1750(2003) [PubMed: 12421807] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
[4]	"Structure of 6-oxo camphor hydrolase H122A mutant bound to its natural product, (2S,4S)-alpha-campholinic acid: mutant structure suggests an atypical mode of transition state binding for a crotonase homolog." Leonard P.M., Grogan G. J. Biol. Chem. 279:31312-31317(2004) [PubMed: 15138275] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF323755 Genomic DNA. Translation: AAK50622.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1O8U	X-ray	2.00	A/B/C/D/E/F	1-257	[»]
1SZO	X-ray	1.90	A/B/C/D/E/F/G/H/I/J/K/L	1-257	[»]

ProteinModelPortal

Q93TU6.

SMR

Q93TU6. Positions 4-252.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR001753. Crotonase_core.
[Graphical view]

Pfam

PF00378. ECH. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q93TU6_9NOCA

Accession

Primary (citable) accession number: Q93TU6

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	January 11, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)