Reviewed, UniProtKB/Swiss-Prot Q93TN0 (PCYA_ANASP)

Names and origin

Protein names

Recommended name:
    Phycocyanobilin:ferredoxin oxidoreductase
    EC=1.3.7.5

Gene names

Name:	pcyA
Ordered Locus Names:	alr3707

Organism

Anabaena sp. (strain PCC 7120) [Complete proteome] [HAMAP]

Taxonomic identifier

103690 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
Catalytic activity	(3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin.
Sequence similarities	Belongs to the HY2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalt ion binding Inferred from electronic annotation. Source: InterPro phycocyanobilin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 245

245

Phycocyanobilin:ferredoxin oxidoreductase

PRO_0000216738

Secondary structure

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245

Helix Strand Turn

Details...

Helix

9 – 12

4

Helix

15 – 31

17

Helix

41 – 43

3

Beta strand

44 – 50

7

Beta strand

53 – 63

11

Beta strand

65 – 77

13

Turn

78 – 80

3

Beta strand

81 – 90

10

Beta strand

98 – 105

8

Beta strand

110 – 118

9

Helix

128 – 135

8

Beta strand

143 – 145

3

Helix

150 – 154

5

Beta strand

160 – 162

3

Helix

167 – 190

24

Helix

196 – 216

21

Helix

219 – 227

9

Helix

229 – 238

10

Sequences

	Sequence		Length	Mass (Da)
	Q93TN0-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 8F6CE652EFEE011A	FASTA	245	27,959
	10 20 30 40 50 60 MSLTSIPSLR EQQHPLIRQL ADCIEEVWHQ HLDLSPYHLP AELGYVEGRL EGEKLTIENR 70 80 90 100 110 120 CYQTPQFRKM HLELAKVGNM LDILHCVMFP RPEYDLPMFG CDLVGGRGQI SAAIADLSPV 130 140 150 160 170 180 HLDRTLPESY NSALTSLNTL NFSQPRELPE WGNIFSDFCI FVRPSSPEEE AMFLGRVREF 190 200 210 220 230 240 LQVHCQGAIA ASPVSAEQKQ QILAGQHNYC SKQQQNDKTR RVLEKAFGVD WAENYMTTVL FDLPE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms." Frankenberg N., Mukougawa K., Kohchi T., Lagarias J.C. Plant Cell 13:965-978(2001) [PubMed: 11283349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120." Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. , Takazawa M., Yamada M., Yasuda M., Tabata S. DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AF339056 Genomic DNA. Translation: AAK38587.1.
BA000019 Genomic DNA. Translation: BAB75406.1.

PIR

AD2269.

RefSeq

NP_487747.1.

3D structure databases

PDBMSD

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2G18	X-ray	2.50	A/B/C/D/E/F/G/H/I/J/K/L	1-245	[»]

ModBase

Search...

Genome annotation databases

GeneID

1107305.

GenomeReviews

Gene locus alr3707 in contig BA000019_GR.

KEGG

ana:alr3707.

NMPDR

fig|103690.1.peg.4014.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

Q93TN0.

Enzyme and pathway databases

BioCyc

NSP103690:ALR3707-MON.

Family and domain databases

HAMAP

MF_00618.
[Tree]

InterPro

IPR009249. Fe_bilin_red.
[Graphical view]

Pfam

PF05996. Fe_bilin_red. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

PCYA_ANASP

Accession

Primary (citable) accession number: Q93TN0

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	December 1, 2001
Last modified:	November 25, 2008
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)