Reviewed, UniProtKB/Swiss-Prot Q93TM9 (PCYA_NOSP7)

Names and originHide

Protein names

Recommended name:
Phycocyanobilin:ferredoxin oxidoreductase
EC=1.3.7.5

Gene names

Name:	pcyA
Ordered Locus Names:	Npun_R5577

Organism

Nostoc punctiforme (strain ATCC 29133 / PCC 73102) [Complete proteome] [HAMAP]

Taxonomic identifier

63737 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributesHide

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)Hide

Function	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. HAMAP MF_00618
Catalytic activity	(3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin. HAMAP MF_00618
Sequence similarities	Belongs to the HY2 family.

OntologiesHide

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalt ion binding Inferred from electronic annotation. Source: InterPro phycocyanobilin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)Hide

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Phycocyanobilin:ferredoxin oxidoreductase HAMAP MF_00618		PRO_0000216740

SequencesHide

	Sequence		Length	Mass (Da)
	Q93TM9-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 20B9A8984F9C64C4	FASTA	245	28,061
	10 20 30 40 50 60 MSFTSMPSLR EQQHPLIRQL ADCIEAAWHQ HLDLSPYHLP DELGYVEGRL EGEKLTIENR 70 80 90 100 110 120 CYQTPQFRKM HLELANIGNM LDILHCVMFP RPQYNLPMFG CDLVGGRGQI SAAIADLSPI 130 140 150 160 170 180 QLERTLPESY TTALAQLPVL NFSQPRELPE WGNIFSDFCI FVRPGSPEEE AMFLSRVREF 190 200 210 220 230 240 LDIHCMQAIA SHPVSVEQVT QNLAGQHNYC TKQQQNDKTR RVLEKAFGPV WAENYMTTVL FDLPT

ReferencesHide

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms." Frankenberg N., Mukougawa K., Kohchi T., Lagarias J.C. Plant Cell 13:965-978(2001) [PubMed: 11283349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C. , Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-referencesHide

Sequence databases
EMBL GenBank DDBJ	AF339057 Genomic DNA. Translation: AAK38588.1. CP001037 Genomic DNA. Translation: ACC83882.1.
RefSeq	YP_001868825.1.
3D structure databases
SMR	Q93TM9. Positions 1-244.
ModBase	Search...
Genome annotation databases
GeneID	6254918.
GenomeReviews	Gene locus Npun_R5577 in contig CP001037_GR.
KEGG	npu:Npun_R5577.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG561233.
OMA	NDKTRRV.
ProtClustDB	PRK02816.
Enzyme and pathway databases
BRENDA	1.3.7.5. 259803.
Family and domain databases
HAMAP	MF_00618. Ferredoxin_bilin_red. [Tree]
InterPro	IPR009249. Ferredoxin-dep_bilin_Rdtase. [Graphical view]
Pfam	PF05996. Fe_bilin_red. 1 hit. [Graphical view]
ProtoNet	Search...

Entry informationHide

Entry name

PCYA_NOSP7

Accession

Primary (citable) accession number: Q93TM9
Secondary accession number(s): B2J6V6

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	December 1, 2001
Last modified:	March 2, 2010
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)