Reviewed, UniProtKB/Swiss-Prot Q93TL5 (PCYA_PROMP)

Names and origin

Protein names

Recommended name:
    Phycocyanobilin:ferredoxin oxidoreductase
    EC=1.3.7.5

Gene names

Name:	pcyA
Ordered Locus Names:	PMM0747

Organism

Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) [Complete proteome] [HAMAP]

Taxonomic identifier

59919 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. HAMAP MF_00618
Catalytic activity	(3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin. HAMAP MF_00618
Sequence similarities	Belongs to the HY2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cobalt ion binding Inferred from electronic annotation. Source: InterPro phycocyanobilin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 241	241	Phycocyanobilin:ferredoxin oxidoreductase HAMAP MF_00618		PRO_0000216743

Sequences

	Sequence		Length	Mass (Da)
	Q93TL5-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: B19E93EB85A45E68	FASTA	241	28,077
	10 20 30 40 50 60 MLSKSLTKTK LIDPLILTLL QNIKVQRSKL NDLNCIEVDP KLSNIISNEE GKELYIENEF 70 80 90 100 110 120 YKAKGFRKLH IEVAEFSKSL KILHCVFFPD PKYDIPIFGM DLVKVNELVS AAIVDLSPSS 130 140 150 160 170 180 KNQNLKYDHL LSHIDKSVFK SKREIPIWGN IFSKNVFFAS LKNESEKNAF CKIVDNYLSV 190 200 210 220 230 240 LIQLSQSTSP DSDYEIIEER INYQKNYCVQ QMKNEKTSLV LLKYFDKVWV DEYIKKVLFD F

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms." Frankenberg N., Mukougawa K., Kohchi T., Lagarias J.C. Plant Cell 13:965-978(2001) [PubMed: 11283349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF352050 Genomic DNA. Translation: AAK38599.1. BX548174 Genomic DNA. Translation: CAE19206.1.
RefSeq	NP_892865.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1726068.
GenomeReviews	Gene locus PMM0747 in contig BX548174_GR.
KEGG	pmm:PMM0747.
NMPDR	fig|59919.1.peg.744.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q93TL5.
OMA	Q93TL5. NDKTRRV.
Enzyme and pathway databases
BioCyc	PMAR167540:PMM0747-MON.
Family and domain databases
HAMAP	MF_00618. [Tree]
InterPro	IPR009249. Ferredoxin-dep_bilin_Rdtase. [Graphical view]
Pfam	PF05996. Fe_bilin_red. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCYA_PROMP

Accession

Primary (citable) accession number: Q93TL5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	December 1, 2001
Last modified:	May 5, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)