Q93SN8 (PEBA_PROMP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
15,16-dihydrobiliverdin:ferredoxin oxidoreductase
EC=1.3.7.2

Gene names

Name:	pebA
Ordered Locus Names:	PMM1593

Organism

Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / MED4) [Complete proteome] [HAMAP]

Taxonomic identifier

59919 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge. HAMAP MF_00792
Catalytic activity	15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IX-alpha + reduced ferredoxin. HAMAP MF_00792
Sequence similarities	Belongs to the HY2 family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phytochromobilin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity Inferred from electronic annotation. Source: EC cobalt ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	15,16-dihydrobiliverdin:ferredoxin oxidoreductase HAMAP MF_00792		PRO_0000216728
Experimental info
	Sequence conflict	47	1	Q → R in AAK38141. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q93SN8 [UniParc]. Last modified September 19, 2003. Version 2. Checksum: D4F215B59B1282D2	FASTA	236	28,340
	10 20 30 40 50 60 MFESLKNFVK TNIEDLDGKE LEISKEFKEH HNKDSKYIIK NWIFESQQYR KWRITKLDGG 70 80 90 100 110 120 DKLQVFNTVA YPNFKSEFPI LGADILWFGT SQKLLAIFDY QPLIQEKKYL QKYCSSLDFI 130 140 150 160 170 180 KNQYSVFDNH KMKNIYDSKK YFSPWVMICR GNKLNLDRDL NNIFCSFVSN YLTINKLHQN 190 200 210 220 230 NQFLDLEQIK NNQIDYDKYS AEKDPADKLF KTFFGETWTE NFINNFLFTL NHNPLK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms." Frankenberg N., Mukougawa K., Kohchi T., Lagarias J.C. Plant Cell 13:965-978(2001) [PubMed: 11283349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation." Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A., Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L., Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C. , Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R., Chisholm S.W. Nature 424:1042-1047(2003) [PubMed: 12917642] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CCMP1986 / MED4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY030300 Genomic DNA. Translation: AAK38141.1. BX548174 Genomic DNA. Translation: CAE20052.1.
RefSeq	NP_893710.1. NC_005072.1.
3D structure databases
ProteinModelPortal	Q93SN8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q93SN8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1726360.
GenomeReviews	Gene locus PMM1593 in contig BX548174_GR.
KEGG	pmm:PMM1593.
NMPDR	fig|59919.1.peg.1589.
PATRIC	23034370. VBIProMar68066_1834.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	NOG41209.
HOGENOM	HBG635096.
OMA	GFRRWRV.
PhylomeDB	Q93SN8.
ProtClustDB	PRK13246.
Enzyme and pathway databases
BioCyc	PMAR167540:PMM1593-MONOMER.
Family and domain databases
HAMAP	MF_00792. PebA. [Tree]
InterPro	IPR023658. DiHydbiliverdin_OxRdtase. IPR009249. Ferredoxin-dep_bilin_Rdtase. [Graphical view]
KO	K05369.
Pfam	PF05996. Fe_bilin_red. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PEBA_PROMP

Accession

Primary (citable) accession number: Q93SN8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 12, 2003
Last sequence update:	September 19, 2003
Last modified:	January 25, 2012
This is version 60 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program