ID   Q93RS3_STRCO            Unreviewed;       362 AA.
AC   Q93RS3;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Integral membrane protein {ECO:0000313|EMBL:CAC37542.1};
GN   OrderedLocusNames=SCO6321 {ECO:0000313|EMBL:CAC37542.1};
GN   ORFNames=SCIF3.23 {ECO:0000313|EMBL:CAC37542.1};
OS   Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145).
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
OX   NCBI_TaxID=100226 {ECO:0000313|EMBL:CAC37542.1, ECO:0000313|Proteomes:UP000001973};
RN   [1] {ECO:0000313|EMBL:CAC37542.1, ECO:0000313|Proteomes:UP000001973}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-471 / A3(2) / M145
RC   {ECO:0000313|Proteomes:UP000001973};
RX   PubMed=12000953; DOI=10.1038/417141a;
RA   Bentley S.D., Chater K.F., Cerdeno-Tarraga A.M., Challis G.L.,
RA   Thomson N.R., James K.D., Harris D.E., Quail M.A., Kieser H., Harper D.,
RA   Bateman A., Brown S., Chandra G., Chen C.W., Collins M., Cronin A.,
RA   Fraser A., Goble A., Hidalgo J., Hornsby T., Howarth S., Huang C.H.,
RA   Kieser T., Larke L., Murphy L., Oliver K., O'Neil S., Rabbinowitsch E.,
RA   Rajandream M.A., Rutherford K., Rutter S., Seeger K., Saunders D.,
RA   Sharp S., Squares R., Squares S., Taylor K., Warren T., Wietzorrek A.,
RA   Woodward J., Barrell B.G., Parkhill J., Hopwood D.A.;
RT   "Complete genome sequence of the model actinomycete Streptomyces coelicolor
RT   A3(2).";
RL   Nature 417:141-147(2002).
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DR   EMBL; AL939127; CAC37542.1; -; Genomic_DNA.
DR   RefSeq; NP_630416.1; NC_003888.3.
DR   RefSeq; WP_011030823.1; NZ_VNID01000022.1.
DR   AlphaFoldDB; Q93RS3; -.
DR   STRING; 100226.gene:17763980; -.
DR   PaxDb; 100226-SCO6321; -.
DR   PATRIC; fig|100226.15.peg.6433; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_045535_1_1_11; -.
DR   InParanoid; Q93RS3; -.
DR   OrthoDB; 4935951at2; -.
DR   PhylomeDB; Q93RS3; -.
DR   Proteomes; UP000001973; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016791; F:phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001973};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        59..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          135..349
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   362 AA;  37975 MW;  5E166D2E9E9E3C17 CRC64;
     MTVDKSSGSV ALAWMPWAAM TVVAVTDIIA GPDVGFLPLV SLGPAFASLV GDWRRTARIG
     AVALALTVAL GLYDGLFDGR RGLTACLSVA GVTGVGLAAA VIRERREAEL ANVRSIAESA
     QRVLLRPVPL TVGPLQMAVS YTSAIAEARI GGDLYEVVAS PYGVRVIVGD VQGKGLAAVE
     TAAVVLGAFR EAAHDEPDLV KLGERLERSL SRELEGEKFV TAVLAEIGAG DEAVFLNFGH
     PAPMVVRADG TVDFPEPPSY ALPLGLGMEG TEGPQPYRVG FVPGDQLLLY TDGVTEARDE
     EDAFYPLAHR ACLLNEPDAH HALEALRADL SEHAVGPPHD DAAMLLVRHQ GGPVGGESRK
     PQ
//