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Q93QD4 (FABD_STAAU) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Malonyl CoA-acyl carrier protein transacylase

Short name=MCT
EC=2.3.1.39
Gene names
Name:fabD
OrganismStaphylococcus aureus
Taxonomic identifier1280 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Malonyl-CoA + [acyl-carrier-protein] = CoA + malonyl-[acyl-carrier-protein].

Pathway

Lipid metabolism; fatty acid biosynthesis.

Sequence similarities

Belongs to the FabD family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Malonyl CoA-acyl carrier protein transacylase
PRO_0000194220

Sites

Active site891 By similarity
Active site1991 By similarity

Experimental info

Sequence conflict231F → Y in BAD72836. Ref.2
Sequence conflict531E → D in BAD72836. Ref.2
Sequence conflict2201R → H in BAD72836. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q93QD4 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: C28AEC6CC50805C2

FASTA30833,635
        10         20         30         40         50         60 
MSKTAIIFPG QGAQKVGMAQ DLFNNNDQAT EILTSAANTL DFDILETMFT DEEGKLGETE 

        70         80         90        100        110        120 
NTQPALLTHS SALLAALKNL NPDFTMGHSL GEYSSLVAAD VLSFEDAVKI VRKRGQLMAQ 

       130        140        150        160        170        180 
AFPTGVGSMA AVLGLDFDKV DEICKSLSSD DKIIEPANIN CPGQIVVSGH KALIDELVEK 

       190        200        210        220        230        240 
GKSLGAKRVM PLAVSGPFHS SLMKVIEEDF SSYINQFEWR DAKFPVVQNV NAQGETDKEV 

       250        260        270        280        290        300 
IKSNMVKQLY SPVQFINSTE WLIDQGVDHF IEIGPGKVLS GLIKKINRDV KLTSIQTLED 


VKGWNEND 

« Hide

References

[1]"Cloning and characterization of S.aureus malonyl-CoA:ACP S-malonyl transferase."
Lin A.H., Choi G.H., McCroskey M., Harris D.W., Murray R.W., Rockenbach S.K., Curry K.A., Marotti K.R.
Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Cloning and expression of Staphylococcus aureus Smith fab genes."
Morita Y., Ikeno S., Tsuchiya K.S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 6-303.
Strain: Smith.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF275318 Genomic DNA. Translation: AAK69406.1.
AB195288 Genomic DNA. Translation: BAD72836.1.

3D structure databases

ProteinModelPortalQ93QD4.
SMRQ93QD4. Positions 2-305.
ModBaseSearch...
MobiDBSearch...

Chemistry

ChEMBLCHEMBL1075258.

Proteomic databases

PRIDEQ93QD4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG0331.

Enzyme and pathway databases

UniPathwayUPA00094.

Family and domain databases

Gene3D3.40.366.10. 2 hits.
InterProIPR001227. Ac_transferase_dom.
IPR014043. Acyl_transferase.
IPR016035. Acyl_Trfase/lysoPLipase.
IPR024925. Malonyl_CoA-ACP_transAc.
IPR004410. Malonyl_CoA-ACP_transAc_FabD.
IPR016036. Malonyl_transacylase_ACP-bd.
[Graphical view]
PfamPF00698. Acyl_transf_1. 1 hit.
[Graphical view]
PIRSFPIRSF000446. Mct. 1 hit.
SUPFAMSSF52151. SSF52151. 2 hits.
SSF55048. SSF55048. 1 hit.
TIGRFAMsTIGR00128. fabD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameFABD_STAAU
AccessionPrimary (citable) accession number: Q93QD4
Secondary accession number(s): Q5TKS3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: December 1, 2001
Last modified: December 11, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways