Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q93JQ8

- ASSY_RHOFA

UniProt

Q93JQ8 - ASSY_RHOFA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Argininosuccinate synthase

Gene

argG

Organism
Rhodococcus fascians
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATP; via amide nitrogen and carbonyl oxygenUniRule annotation
Binding sitei84 – 841CitrullineUniRule annotation
Binding sitei114 – 1141ATP; via amide nitrogenUniRule annotation
Binding sitei116 – 1161AspartateUniRule annotation
Binding sitei120 – 1201AspartateUniRule annotation
Binding sitei120 – 1201CitrullineUniRule annotation
Binding sitei121 – 1211AspartateUniRule annotation
Binding sitei124 – 1241CitrullineUniRule annotation
Binding sitei173 – 1731CitrullineUniRule annotation
Binding sitei182 – 1821CitrullineUniRule annotation
Binding sitei258 – 2581CitrullineUniRule annotation
Binding sitei270 – 2701CitrullineUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 149ATPUniRule annotation

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthaseUniRule annotation (EC:6.3.4.5UniRule annotation)
Alternative name(s):
Citrulline--aspartate ligaseUniRule annotation
Gene namesi
Name:argGUniRule annotation
Synonyms:attB
OrganismiRhodococcus fascians
Taxonomic identifieri1828 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeNocardiaceaeRhodococcus

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 395395Argininosuccinate synthasePRO_0000148632Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ93JQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the argininosuccinate synthase family. Type 1 subfamily.UniRule annotation

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q93JQ8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSIVLAYSGG LDTSVAVHWL KERYQTEVIA YCANLGQIED LEAVSKRATA
60 70 80 90 100
AGASEVIVED VRDLFLHDYA IPALAAGAAY EGKYLLAAPL SRPLIAERLV
110 120 130 140 150
SIARERGASA VAHGATGKGN DQVRFYTSVR ALAPELDILA PVIDWEMTSR
160 170 180 190 200
GSEIAYADRH GIDVGVSKTT PYSIDTNIWG TSIECGDLDL IDHAPPPDAW
210 220 230 240 250
QITTAPVQAP DRPTTITIEF EAGIPVALDG RKLDLIDLVS ELGDTAAANG
260 270 280 290 300
IGRTEILESR IVGFKSRGIY EAPAATVLLA ARTDLEALVL DRETLHHKRS
310 320 330 340 350
IADQYAELVY YGYWFTDLRA ALDAYCARLA HRVTGTVTVE LYKGSARCIG
360 370 380 390
RTSPKYGRYS SALADYEEAD TFLHEAGAGF AYCWALPLTE GVVTR
Length:395
Mass (Da):42,769
Last modified:December 1, 2001 - v1
Checksum:i851FA5BDD147AFDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ311775 Genomic DNA. Translation: CAC43336.1.
RefSeqiYP_007878694.1. NC_021080.1.

Genome annotation databases

GeneIDi15334506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ311775 Genomic DNA. Translation: CAC43336.1 .
RefSeqi YP_007878694.1. NC_021080.1.

3D structure databases

ProteinModelPortali Q93JQ8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 15334506.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The att locus of Rhodococcus fascians strain D188 is essential for full virulence on tobacco through the production of an autoregulatory compound."
    Maes T., Vereecke D., Ritsema T., Cornelis K., Thu H.N., Van Montagu M., Holsters M., Goethals K.
    Mol. Microbiol. 42:13-28(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: D188.

Entry informationi

Entry nameiASSY_RHOFA
AccessioniPrimary (citable) accession number: Q93JQ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3