Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

RAB family

Gene

rab-14

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • defense response to bacterium Source: InterPro
  • endocytic recycling Source: InterPro
  • Golgi to endosome transport Source: InterPro
  • phagolysosome assembly involved in apoptotic cell clearance Source: WormBase
  • phagosome acidification involved in apoptotic cell clearance Source: WormBase
  • regulation of endocytosis Source: GO_Central

Enzyme and pathway databases

ReactomeiR-CEL-6798695. Neutrophil degranulation.
R-CEL-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Submitted name:
RAB familyImported
Gene namesi
Name:rab-14Imported
ORF Names:CELE_K09A9.2Imported, K09A9.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiK09A9.2; CE11974; WBGene00004276; rab-14.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: GOC
  • early endosome Source: WormBase
  • phagocytic vesicle Source: WormBase
  • recycling endosome Source: InterPro
  • trans-Golgi network Source: WormBase

PTM / Processingi

Proteomic databases

EPDiQ93874.
PaxDbiQ93874.

Expressioni

Gene expression databases

BgeeiWBGene00004276.
ExpressionAtlasiQ93874. baseline.

Interactioni

Protein-protein interaction databases

STRINGi6239.K09A9.2.2.

Structurei

3D structure databases

ProteinModelPortaliQ93874.
SMRiQ93874.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0097. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00760000118841.
HOGENOMiHOG000233968.
InParanoidiQ93874.
KOiK07881.
OMAiGVQHKPA.
OrthoDBiEOG091G0QOB.
PhylomeDBiQ93874.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR030702. Rab14.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PANTHERiPTHR24073:SF643. PTHR24073:SF643. 1 hit.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q93874-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT
60 70 80 90 100
RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN
110 120 130 140 150
HLSSWLADAK SLTNPNTAIF LIGNKADLED QRDVPYEEAK AFAEENGLTF
160 170 180 190 200
LECSAKTGSN VEDAFLETAK QIYQNIQDGS LDLNAADTGV QPKQNLPRAA
210
ENNGKKDCNC
Length:210
Mass (Da):23,388
Last modified:February 1, 1997 - v1
Checksum:iDBDE4B52E447656D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB01884.1.
PIRiT23530.
RefSeqiNP_510572.1. NM_078171.4.
UniGeneiCel.7259.

Genome annotation databases

EnsemblMetazoaiK09A9.2.1; K09A9.2.1; WBGene00004276.
K09A9.2.2; K09A9.2.2; WBGene00004276.
GeneIDi181649.
KEGGicel:CELE_K09A9.2.
UCSCiK09A9.2.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB01884.1.
PIRiT23530.
RefSeqiNP_510572.1. NM_078171.4.
UniGeneiCel.7259.

3D structure databases

ProteinModelPortaliQ93874.
SMRiQ93874.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.K09A9.2.2.

Proteomic databases

EPDiQ93874.
PaxDbiQ93874.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK09A9.2.1; K09A9.2.1; WBGene00004276.
K09A9.2.2; K09A9.2.2; WBGene00004276.
GeneIDi181649.
KEGGicel:CELE_K09A9.2.
UCSCiK09A9.2.1. c. elegans.

Organism-specific databases

CTDi181649.
WormBaseiK09A9.2; CE11974; WBGene00004276; rab-14.

Phylogenomic databases

eggNOGiKOG0097. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00760000118841.
HOGENOMiHOG000233968.
InParanoidiQ93874.
KOiK07881.
OMAiGVQHKPA.
OrthoDBiEOG091G0QOB.
PhylomeDBiQ93874.

Enzyme and pathway databases

ReactomeiR-CEL-6798695. Neutrophil degranulation.
R-CEL-8876198. RAB GEFs exchange GTP for GDP on RABs.

Gene expression databases

BgeeiWBGene00004276.
ExpressionAtlasiQ93874. baseline.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR030702. Rab14.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
PANTHERiPTHR24073:SF643. PTHR24073:SF643. 1 hit.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ93874_CAEEL
AccessioniPrimary (citable) accession number: Q93874
Entry historyiIntegrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: June 7, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.