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Protein
Submitted name:

Inward Rectifying K (Potassium) channel family

Gene

irk-3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • potassium ion import Source: GO_Central
  • short-term memory Source: WormBase
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Voltage-gated channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Potassium transportUniRule annotationSAAS annotation, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Inward Rectifying K (Potassium) channel familyImported
Gene namesi
Name:irk-3Imported
ORF Names:CELE_K04G11.5Imported, K04G11.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiK04G11.5a; CE35580; WBGene00002151; irk-3.

Subcellular locationi

  • Membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei78 – 103HelicalSequence analysisAdd BLAST26
Transmembranei150 – 177HelicalSequence analysisAdd BLAST28

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ93849.

Expressioni

Gene expression databases

BgeeiWBGene00002151.

Structurei

3D structure databases

ProteinModelPortaliQ93849.
SMRiQ93849.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00830000128392.
HOGENOMiHOG000237325.
InParanoidiQ93849.
KOiK05330.
OMAiHVINEDS.
OrthoDBiEOG091G08HC.
PhylomeDBiQ93849.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PRINTSiPR01320. KIRCHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q93849-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLAEELERL SGENGAKKEL NGWRLSSSAP ELGVQRARLV SKDGKTLLNN
60 70 80 90 100
IQIPERFRQA YKWRYCRNWF HLIIECNWRT ICILFLLGFI VSWTIFAVIY
110 120 130 140 150
YVISRLKTVK KDESCIANVD TLISAFLFSM ESQHTIGYGL RYMTDLCPPA
160 170 180 190 200
YLTLCVQCVV GVFLQTILAG IVIAKILRPK KRRQEMRFSR MAVIGPLDEH
210 220 230 240 250
DKRPTLMIRL ADIQEKLFLA ESHVRLYMAC SKINSRGDRE LIGVKDMNVG
260 270 280 290 300
YDSGWDRVLL LWPIIVRHVI NEDSPLYGMS RENIVKADFE LIMTVEGIVE
310 320 330 340 350
ATGMTFQART SFLPDEILWG YKFKPMVLMN EKLSKYEVHY SFFDQTERVC
360 370
DFDAQTIETE ETEDEHHHNA SGFL
Length:374
Mass (Da):43,332
Last modified:July 5, 2004 - v3
Checksum:iDA1EC0284001122A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB01762.3.
PIRiT23319.
RefSeqiNP_510395.3. NM_077994.5.
UniGeneiCel.19837.

Genome annotation databases

EnsemblMetazoaiK04G11.5; K04G11.5; WBGene00002151.
GeneIDi191696.
KEGGicel:CELE_K04G11.5.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB01762.3.
PIRiT23319.
RefSeqiNP_510395.3. NM_077994.5.
UniGeneiCel.19837.

3D structure databases

ProteinModelPortaliQ93849.
SMRiQ93849.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ93849.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiK04G11.5; K04G11.5; WBGene00002151.
GeneIDi191696.
KEGGicel:CELE_K04G11.5.

Organism-specific databases

CTDi191696.
WormBaseiK04G11.5a; CE35580; WBGene00002151; irk-3.

Phylogenomic databases

eggNOGiKOG3827. Eukaryota.
ENOG410XQ62. LUCA.
GeneTreeiENSGT00830000128392.
HOGENOMiHOG000237325.
InParanoidiQ93849.
KOiK05330.
OMAiHVINEDS.
OrthoDBiEOG091G08HC.
PhylomeDBiQ93849.

Miscellaneous databases

PROiQ93849.

Gene expression databases

BgeeiWBGene00002151.

Family and domain databases

Gene3Di2.60.40.1400. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR016449. K_chnl_inward-rec_Kir.
IPR013518. K_chnl_inward-rec_Kir_cyto.
[Graphical view]
PANTHERiPTHR11767. PTHR11767. 1 hit.
PfamiPF01007. IRK. 1 hit.
[Graphical view]
PRINTSiPR01320. KIRCHANNEL.
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ93849_CAEEL
AccessioniPrimary (citable) accession number: Q93849
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: July 5, 2004
Last modified: November 2, 2016
This is version 134 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.