SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q937W7

- MASZ_RHILV

UniProt

Q937W7 - MASZ_RHILV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Malate synthase G
Gene
glcB, masG
Organism
Rhizobium leguminosarum bv. viciae
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA By similarity.UniRule annotation

Catalytic activityi

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei116 – 1161Acetyl-CoA; via carbonyl oxygen By similarity
Binding sitei274 – 2741Acetyl-CoA By similarity
Binding sitei311 – 3111Acetyl-CoA By similarity
Active sitei338 – 3381Proton acceptor By similarity
Binding sitei338 – 3381Glyoxylate By similarity
Metal bindingi430 – 4301Magnesium By similarity
Binding sitei430 – 4301Glyoxylate By similarity
Metal bindingi458 – 4581Magnesium By similarity
Binding sitei539 – 5391Acetyl-CoA; via carbonyl oxygen By similarity
Active sitei629 – 6291Proton donor By similarity

GO - Molecular functioni

  1. malate synthase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-HAMAP
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Glyoxylate bypass, Tricarboxylic acid cycle

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00703; UER00720.

Names & Taxonomyi

Protein namesi
Recommended name:
Malate synthase G (EC:2.3.3.9)
Gene namesi
Name:glcB
Synonyms:masG
OrganismiRhizobium leguminosarum bv. viciae
Taxonomic identifieri387 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 723723Malate synthase GUniRule annotation
PRO_0000166897Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei615 – 6151Cysteine sulfenic acid (-SOH) By similarity

Keywords - PTMi

Oxidation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ937W7.
SMRiQ937W7. Positions 3-722.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni123 – 1242Acetyl-CoA binding By similarity
Regioni455 – 4584Glyoxylate binding By similarity

Sequence similaritiesi

Family and domain databases

Gene3Di2.170.170.11. 2 hits.
HAMAPiMF_00641. Malate_synth_G.
InterProiIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PfamiPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMiSSF51645. SSF51645. 1 hit.
TIGRFAMsiTIGR01345. malate_syn_G. 1 hit.

Sequencei

Sequence statusi: Complete.

Q937W7-1 [UniParc]FASTAAdd to Basket

« Hide

MSRVDKNGLA IETVLHDFLV EEVLPGLAVD ADKFFADFSA IVHDLAPKNC    50
ALLAKRDELQ VKIDDWYRRH GAPADMDEYQ SFLREIGYLL PEGSDFQVST 100
QNVDPEIASI AGPQLVVPVM NARYALNAAN ARWGSLYDAL YGTDAIPESD 150
GAEKGKSYNP KRGEKVIAWV RDFLDTSAPL QDCRWKDVGS FAVKDGALVV 200
RSIDGEQAML TDGKHFAGYR GDAAAPTHIL LKNNGIHIEI VIDAATTIGK 250
ADSAHISDVW LESAITTIMD CEDSIAAVDA EDKVVVYRNW LGLMKGDLQE 300
EVAKGGTSFI RTLNPDLQYA GPDGAAFEVH RRSLMLVRNV GHLMTNPAIL 350
DRDGNEVPEG IMDAAITGLI ALYDIGPSGR RKNSRTGSMY VVKPKMHGPE 400
EVAFAVEIFS RVEDALGLPR NTIKMGIMDE ERRTTVNLKE CIRAARERVV 450
FINTGFLDRT GDEIHTSMEA GPMIRKGDMR QAAWISAYEN WNVDIGLECG 500
LAGHAQIGKG MWAMPDLMAA MLEQKIAHPK AGANTAWVPS PTAATLHATH 550
YHRVNVARVQ QGLKDRARAK LSDILSVPVA VRPNWTPEEI QRELDNNAQG 600
ILGYVVRWVD QGVGCSKVPD INNVGLMEDR ATLRISAQHM ANWLHHKVVT 650
EAQIIETMRR MAAVVDRQNA SDPAYRPMAG NFDDSIAFQA ALDLVLKGRE 700
QPNGYTEPVL HRRRLELKAK QAA 723
Length:723
Mass (Da):79,678
Last modified:December 1, 2001 - v1
Checksum:i4E879906CFD64444
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY059637 Genomic DNA. Translation: AAL17965.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY059637 Genomic DNA. Translation: AAL17965.1 .

3D structure databases

ProteinModelPortali Q937W7.
SMRi Q937W7. Positions 3-722.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00703 ; UER00720 .

Family and domain databases

Gene3Di 2.170.170.11. 2 hits.
HAMAPi MF_00641. Malate_synth_G.
InterProi IPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view ]
Pfami PF01274. Malate_synthase. 1 hit.
[Graphical view ]
SUPFAMi SSF51645. SSF51645. 1 hit.
TIGRFAMsi TIGR01345. malate_syn_G. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Malate synthase gene from Rhizobium leguminosarum."
    Garcia de los Santos A., Hynes M.F.
    Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: VF39.

Entry informationi

Entry nameiMASZ_RHILV
AccessioniPrimary (citable) accession number: Q937W7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi