Reviewed,
UniProtKB/Swiss-Prot Q937L4 (CPNA_COMTE)
Last modified
June 16, 2009.
Version 33.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Cyclopentanol dehydrogenase EC=1.1.1.163 | ||||
| Gene names |
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| Organism | Comamonas testosteroni (Pseudomonas testosteroni) | ||||
| Taxonomic identifier | 285 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Comamonadaceae › Comamonas |
Protein attributes
| Sequence length | 250 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity towards cyclohexanol. Ref.1 |
| Catalytic activity | Cyclopentanol + NAD+ = cyclopentanone + NADH. |
| Pathway | Alcohol metabolism; cyclopentanol degradation; 5-valerolactone from cyclopentanol: step 1/2. |
| Sequence similarities | Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro cyclopentanol dehydrogenase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Cloning of Baeyer-Villiger monooxygenases from Comamonas, Xanthobacter and Rhodococcus via PCR with highly degenerate primers." van Beilen J.B., Mourlane F., Seeger M.A., Kovac J., Li Z., Smits T.H.M., Fritsche U., Witholt B. Environ. Microbiol. 5:174-182(2003) [PubMed: 12588297] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION. |
Cross-references
Sequence databases | |
|---|---|
| AJ418060 Genomic DNA. Translation: CAD10799.1. | |
3D structure databases | |
| HSSP | HSSP built from PDB template 1NFF based on UniProtKB Q10855. |
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 1.1.1.163. 4566. |
Family and domain databases | |
| InterPro | IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| PANTHER | PTHR19410. ADH_short_C2. 1 hit. |
| Pfam | PF00106. adh_short. 1 hit. [Graphical view] |
| PRINTS | PR00081. GDHRDH. PR00080. SDRFAMILY. |
| ProtoNet | Search... |
Entry information
| Entry name | CPNA_COMTE | ||||||||
| Accession | Primary (citable) accession number: Q937L4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


