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Protein

Xylulose-5-phosphate phosphoketolase

Gene

xpkA

Organism
Lactobacillus pentosus
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.

Cofactori

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandThiamine pyrophosphate

Enzyme and pathway databases

BRENDAi4.1.2.9 2886

Names & Taxonomyi

Protein namesi
Recommended name:
Xylulose-5-phosphate phosphoketolase (EC:4.1.2.9)
Gene namesi
Name:xpkA
OrganismiLactobacillus pentosus
Taxonomic identifieri1589 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001938682 – 788Xylulose-5-phosphate phosphoketolaseAdd BLAST787

Expressioni

Inductioni

Induced by sugars that are fermented by the phosphoketolase pathway (PKP) and repressed by glucose mediated by carbon catabolite protein A and by the mannose phosphoenolpyruvate phosphotransferase system.

Interactioni

Subunit structurei

Homohexamer.Curated

Structurei

3D structure databases

SMRiQ937F6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XFP family.Curated

Family and domain databases

Gene3Di3.40.50.920, 1 hit
HAMAPiMF_01403 Phosphoketolase, 1 hit
InterProiView protein in InterPro
IPR023962 Phosphoketolase
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005593 Xul5P/Fru6P_PKetolase
IPR018969 Xul5P/Fru6P_PKetolase_C
IPR019790 Xul5P/Fru6P_PKetolase_CS
IPR018970 Xul5P/Fru6P_PKetolase_N
IPR019789 Xul5P/Fru6P_PKetolase_ThDP_BS
PANTHERiPTHR31273 PTHR31273, 1 hit
PfamiView protein in Pfam
PF03894 XFP, 1 hit
PF09363 XFP_C, 1 hit
PF09364 XFP_N, 1 hit
PIRSFiPIRSF017245 Phosphoketolase, 1 hit
SUPFAMiSSF52518 SSF52518, 2 hits
PROSITEiView protein in PROSITE
PS60002 PHOSPHOKETOLASE_1, 1 hit
PS60003 PHOSPHOKETOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q937F6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTDYSSPAY LQKVDKYWRA ANYLSVGQLY LKDNPLLQRP LKASDVKVHP
60 70 80 90 100
IGHWGTIAGQ NFIYAHLNRV INKYGLKMFY VEGPGHGGQV MVSNSYLDGT
110 120 130 140 150
YTDIYPEITQ DVEGMQKLFK QFSFPGGVAS HAAPETPGSI HEGGELGYSI
160 170 180 190 200
SHGVGAILDN PDEIAAVVVG DGESETGPLA TSWQSTKFIN PINDGAVLPI
210 220 230 240 250
LNLNGFKISN PTIFGRTSDE KIKQYFESMN WEPIFVEGDD PEKVHPALAK
260 270 280 290 300
AMDEAVEKIK AIQKNAREND DATLPVWPMI VFRAPKGWTG PKSWDGDKIE
310 320 330 340 350
GSFRAHQIPI PVDQTDMEHA DALVDWLESY QPKELFNEDG SLKDDIKEII
360 370 380 390 400
PTGDARMAAN PITNGGVDPK ALNLPNFRDY AVDTSKHGAN VKQDMIVWSD
410 420 430 440 450
YLRDVIKKNP DNFRLFGPDE TMSNRLYGVF ETTNRQWMED IHPDSDQYEA
460 470 480 490 500
PAGRVLDAQL SEHQAEGWLE GYVLTGRHGL FASYEAFLRV VDSMLTQHFK
510 520 530 540 550
WLRKANELDW RKKYPSLNII AASTVFQQDH NGYTHQDPGA LTHLAEKKPE
560 570 580 590 600
YIREYLPADA NSLLAVGDVI FRSQEKINYV VTSKHPRQQW FSIEEAKQLV
610 620 630 640 650
DNGLGIIDWA STDQGSEPDI VFAAAGTEPT LETLAAIQLL HDSFPDMKIR
660 670 680 690 700
FVNVVDILKL RSPEKDPRGL SDAEFDHYFT KDKPVVFAFH GYEDLVRDIF
710 720 730 740 750
FDRHNHNLHV HGYRENGDIT TPFDVRVMNQ MDRFDLAKSA IAAQPAMENT
760 770 780
GAAFVQDMDN MLAKHNAYIR DAGTDLPEVN DWQWKGLK
Length:788
Mass (Da):88,705
Last modified:January 23, 2007 - v3
Checksum:iC9AE9E7819CF8753
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ309011 Genomic DNA Translation: CAC84393.1
RefSeqiWP_050339622.1, NZ_MJHF01000008.1

Similar proteinsi

Entry informationi

Entry nameiXPKA_LACPE
AccessioniPrimary (citable) accession number: Q937F6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 48 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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