swan-2

Functionⁱ

GO - Biological processⁱ

response to heat
Source: WormBase
Inferred from genetic interactionⁱ
- 20940704
response to osmotic stress
Source: WormBase
Inferred from mutant phenotypeⁱ
- 20940704

Enzyme and pathway databases

Reactomeⁱ	R-CEL-8951664. Neddylation.
SignaLinkⁱ	Q93759.

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Seven WD repeats, AN11 familyImported
Gene namesⁱ	Name:swan-2Imported ORF Names:CELE_F53C11.7Imported, F53C11.7Imported
Organismⁱ	Caenorhabditis elegansImported
Taxonomic identifierⁱ	6239 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis
Proteomesⁱ	UP000001940 Componentⁱ: Chromosome V

Organism-specific databases

WormBase More...WormBaseⁱ	F53C11.7; CE24997; WBGene00009976; swan-2.

WormBaseⁱ

F53C11.7; CE24997; WBGene00009976; swan-2.

Subcellular locationⁱ

GO - Cellular componentⁱ

nucleus Source: GO_Central

Complete GO annotation...

PTM / Processingⁱ

Proteomic databases

EPDⁱ	Q93759.
PaxDbⁱ	Q93759.
PeptideAtlas More...PeptideAtlasⁱ	Q93759.

Expressionⁱ

Gene expression databases

Bgeeⁱ	WBGene00009976.

Bgeeⁱ

WBGene00009976.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	6239.F53C11.7.1.

STRINGⁱ

6239.F53C11.7.1.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q93759.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	251 – 440	WD_REPEATS_REGIONInterPro annotationAdd BLAST	190
Repeatⁱ	308 – 350	WDPROSITE-ProRule annotationAdd BLAST	43
Repeatⁱ	398 – 432	WDPROSITE-ProRule annotationAdd BLAST	35

Keywords - Domainⁱ

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG0290. Eukaryota. ENOG410XQ78. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006939.
HOGENOMⁱ	HOG000260968.
InParanoidⁱ	Q93759.
KEGG Orthology (KO) More...KOⁱ	K11805.
OMAⁱ	GSHICTA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G08UU.
PhylomeDBⁱ	Q93759.

Family and domain databases

Gene3Dⁱ	2.130.10.10. 2 hits.
InterProⁱ	View protein in InterPro IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00400. WD40. 2 hits.
SMARTⁱ	View protein in SMART SM00320. WD40. 4 hits.
SUPFAMⁱ	SSF50978. SSF50978. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00678. WD_REPEATS_1. 1 hit. PS50082. WD_REPEATS_2. 2 hits. PS50294. WD_REPEATS_REGION. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q93759-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MIDQSQAAPS SSTSSSHLMH HHSNNYPSYT NPSASSSNHS NMGHPNASTG 
        60         70         80         90        100
QTSAVQRMDP FNQIPSELYG SASSTSIAAS TRQPSSQSQP SQQFRQMPAD 
       110        120        130        140        150
LGASTSTMHS VAPIDIYDNY GNASTSDLRR SSVRGDPRRK EIYAYNAPFT 
       160        170        180        190        200
LFSHGWSAAT DPSRKFRLAV SSFIEEYSNK IHIVQLDEEA GELVHRSTFD 
       210        220        230        240        250
HPYPATKIMW IPDQKGTFPD LLATSGDYLR LWRIGTDNNA CIESLLNTNR 
       260        270        280        290        300
TAEYCAPLTS FDWNELDMNL IGTSSIDTTC TVWQLETGQA IGTTRPTAAI 
       310        320        330        340        350
DGTVRTQLIA HDKEVFDISF SRGSAQIFAS VGADGSLRLF DLRRLEHSTI 
       360        370        380        390        400
MYEDPQRQPL LRLAWNRNDH NYIATFGQDS KEVLILDLRL PCTPVARLRN 
       410        420        430        440        450
HEATINGLSW APHSGSHICT AGDDYQALIW DVHEMPKPIN DPILAYRAQA 
       460        470 
EVNQIHWSSS FPDWISICSD NKLEILRV

Length:478

Mass (Da):53,196

Last modified:May 1, 2000 - v2

Checksum:ⁱ663E13EBA3E95096

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284605 Genomic DNA. Translation: CAB02116.2.
PIRⁱ	T22554.
NCBI Reference Sequences More...RefSeqⁱ	NP_506417.1. NM_074016.5.
UniGeneⁱ	Cel.17355.

Genome annotation databases

EnsemblMetazoaⁱ	F53C11.7.1; F53C11.7.1; WBGene00009976. F53C11.7.2; F53C11.7.2; WBGene00009976.
GeneIDⁱ	179875.
KEGGⁱ	cel:CELE_F53C11.7.
UCSC genome browser More...UCSCⁱ	F53C11.7.1. c. elegans.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BX284605 Genomic DNA. Translation: CAB02116.2.
PIRⁱ	T22554.
NCBI Reference Sequences More...RefSeqⁱ	NP_506417.1. NM_074016.5.
UniGeneⁱ	Cel.17355.

3D structure databases

ProteinModelPortalⁱ	Q93759.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	6239.F53C11.7.1.

STRINGⁱ

6239.F53C11.7.1.

Proteomic databases

EPDⁱ	Q93759.
PaxDbⁱ	Q93759.
PeptideAtlas More...PeptideAtlasⁱ	Q93759.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblMetazoaⁱ	F53C11.7.1; F53C11.7.1; WBGene00009976. F53C11.7.2; F53C11.7.2; WBGene00009976.
GeneIDⁱ	179875.
KEGGⁱ	cel:CELE_F53C11.7.
UCSC genome browser More...UCSCⁱ	F53C11.7.1. c. elegans.

Organism-specific databases

CTDⁱ	179875.
WormBase More...WormBaseⁱ	F53C11.7; CE24997; WBGene00009976; swan-2.

Phylogenomic databases

eggNOGⁱ	KOG0290. Eukaryota. ENOG410XQ78. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000006939.
HOGENOMⁱ	HOG000260968.
InParanoidⁱ	Q93759.
KEGG Orthology (KO) More...KOⁱ	K11805.
OMAⁱ	GSHICTA.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G08UU.
PhylomeDBⁱ	Q93759.

Enzyme and pathway databases

Reactomeⁱ	R-CEL-8951664. Neddylation.
SignaLinkⁱ	Q93759.

Gene expression databases

Bgeeⁱ	WBGene00009976.

Bgeeⁱ

WBGene00009976.

Family and domain databases

Gene3Dⁱ	2.130.10.10. 2 hits.
InterProⁱ	View protein in InterPro IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00400. WD40. 2 hits.
SMARTⁱ	View protein in SMART SM00320. WD40. 4 hits.
SUPFAMⁱ	SSF50978. SSF50978. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00678. WD_REPEATS_1. 1 hit. PS50082. WD_REPEATS_2. 2 hits. PS50294. WD_REPEATS_REGION. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q93759_CAEEL
Accessionⁱ	Q93759Primary (citable) accession number: Q93759
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 1, 1997
	Last sequence update:	May 1, 2000
	Last modified:	June 7, 2017
	This is version 136 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q93759 (Q93759_CAEEL)

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Seven WD repeats, AN11 family

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ