ID   Q934U6_SALTI            Unreviewed;       380 AA.
AC   Q934U6;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   RecName: Full=ribonucleoside-diphosphate reductase {ECO:0000256|ARBA:ARBA00012274};
DE            EC=1.17.4.1 {ECO:0000256|ARBA:ARBA00012274};
GN   Name=nrdB {ECO:0000313|EMBL:ECV8216635.1};
GN   OrderedLocusNames=HCM2.0121c {ECO:0000313|EMBL:CAD09988.1};
GN   ORFNames=CAJ80_08525 {ECO:0000313|EMBL:EDG8901496.1}, CC907_10980
GN   {ECO:0000313|EMBL:EDI0994145.1}, DNV09_11995
GN   {ECO:0000313|EMBL:EBV1033388.1}, EBC38_15305
GN   {ECO:0000313|EMBL:EBZ4083157.1}, ELQ62_14455
GN   {ECO:0000313|EMBL:ECA4925108.1}, ZZ17_13250
GN   {ECO:0000313|EMBL:ECV8216635.1};
OS   Salmonella typhi.
OG   Plasmid pHCM2 {ECO:0000313|EMBL:CAD09988.1,
OG   ECO:0000313|Proteomes:UP000000541}.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370 {ECO:0000313|EMBL:CAD09988.1, ECO:0000313|Proteomes:UP000000541};
RN   [1] {ECO:0000313|EMBL:CAD09988.1, ECO:0000313|Proteomes:UP000000541}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18 {ECO:0000313|EMBL:CAD09988.1,
RC   ECO:0000313|Proteomes:UP000000541};
RC   PLASMID=pHCM2 {ECO:0000313|EMBL:CAD09988.1,
RC   ECO:0000313|Proteomes:UP000000541};
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.,
RA   Rutherford K., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2] {ECO:0000313|EMBL:ECA4925108.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=132015 {ECO:0000313|EMBL:EDG8901496.1}, 14549
RC   {ECO:0000313|EMBL:ECV8216635.1}, 348081
RC   {ECO:0000313|EMBL:EDI0994145.1}, 531284
RC   {ECO:0000313|EMBL:EBV1033388.1}, 619925
RC   {ECO:0000313|EMBL:EBZ4083157.1}, and 656788
RC   {ECO:0000313|EMBL:ECA4925108.1};
RA   Ashton P.M., Dallman T., Nair S., De Pinna E., Peters T., Grant K.;
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC         Evidence={ECO:0000256|ARBA:ARBA00001962};
CC   -!- SIMILARITY: Belongs to the ribonucleoside diphosphate reductase small
CC       chain family. {ECO:0000256|ARBA:ARBA00009303}.
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DR   EMBL; AL513384; CAD09988.1; -; Genomic_DNA.
DR   EMBL; AAHEEH010000016; EBV1033388.1; -; Genomic_DNA.
DR   EMBL; AAHRAJ010000018; EBZ4083157.1; -; Genomic_DNA.
DR   EMBL; AAHUNO010000019; ECA4925108.1; -; Genomic_DNA.
DR   EMBL; AAKUKE010000018; ECV8216635.1; -; Genomic_DNA.
DR   EMBL; AAMFRD010000010; EDG8901496.1; -; Genomic_DNA.
DR   EMBL; AAMJVG010000014; EDI0994145.1; -; Genomic_DNA.
DR   RefSeq; NP_569593.1; NC_003385.1.
DR   RefSeq; WP_011011111.1; NZ_UCTR01000018.1.
DR   AlphaFoldDB; Q934U6; -.
DR   KEGG; sty:HCM2.0121c; -.
DR   eggNOG; COG0208; Bacteria.
DR   HOGENOM; CLU_062403_0_0_6; -.
DR   OMA; WIANESK; -.
DR   UniPathway; UPA00326; -.
DR   Proteomes; UP000000541; Plasmid pHCM2.
DR   GO; GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:UniProtKB-EC.
DR   GO; GO:0009263; P:deoxyribonucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd01049; RNRR2; 1.
DR   Gene3D; 1.10.620.20; Ribonucleotide Reductase, subunit A; 1.
DR   InterPro; IPR009078; Ferritin-like_SF.
DR   InterPro; IPR012348; RNR-like.
DR   InterPro; IPR033909; RNR_small.
DR   InterPro; IPR000358; RNR_small_fam.
DR   PANTHER; PTHR23409; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN; 1.
DR   PANTHER; PTHR23409:SF18; RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2; 1.
DR   Pfam; PF00268; Ribonuc_red_sm; 1.
DR   SUPFAM; SSF47240; Ferritin-like; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000313|EMBL:CAD09988.1};
KW   Plasmid {ECO:0000313|EMBL:CAD09988.1}.
SQ   SEQUENCE   380 AA;  44449 MW;  9368AB567B6695F5 CRC64;
     MTYSTFRLGA NDATKEPMFL GQSVNVARYD QQKYRDFEKL IEKQLSFFWR PEEVDITTDR
     IDFNTKLQEH ERHIFLSNLR YQTLLDSVQG RSPNATLLPL ISIPELETWV ETWSFSETIH
     SRSYTHIIRG MVDDPSIVFD GIVTDEEIIS RAVSISSEYD RLYEMTCARQ HLGEDEFERL
     YISEFDGKPY PLQRQLFRTL VSVNALEAIR FYVSFACTFA FGERKLLEGN TKIMRFIARD
     EALHCEGTER MIRFMRTGRE GLMWKMIAAE EESFIYQTMM DVAGQEMRWA DYLFKDGSMI
     GLNADILKSY VKYRTNLAMR RLGLRQLFPE IKDDPLVWMN KWLLSDTLQI APQEAEQSNY
     LVGQIDSAVD RSGLSQFADL
//