Q934H7 (Q934H7_GEOSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha-galactosidase AgaB EMBL AAG49421.1

Gene names

Name:

agaB EMBL AAG49421.1

Organism

Geobacillus stearothermophilus (Bacillus stearothermophilus) EMBL AAG49421.1

Taxonomic identifier

1422 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	729 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4FNQ
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	alpha-galactosidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q934H7 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: DF7FF8E5D3A016C1	FASTA	729	83,467
	10 20 30 40 50 60 MAVTYNPQTK QFHLRAGKAS YVMQLFRSGY LAHIYWGKAV RDVRGERRFS RLDRAFSPNP 70 80 90 100 110 120 DPSDRTFSLD TLPQEYPAYG NTDFRSPAYQ VQLENGSTVT DLRYKTHRIY KGKPRLNGLP 130 140 150 160 170 180 ATYVEHEQEA ETLEIVLGDA LIGLEVTLQY TAYEKWNVIT RAARFENKGG ERLKLLRALS 190 200 210 220 230 240 MSVDFPTADY DWIHLPGAWG RERWIERRPL VTGVQAAESR RGASSHQQNP FIALVAKNAD 250 260 270 280 290 300 EHQGEVYGFS FVYSGNFLAQ VEVDQFHTAR VSMGINPFDF TWLLQPGESF QTPEVVMVYS 310 320 330 340 350 360 DQGLNGMSQT YHELYRTRLA RGAFRDRERP ILINNWEATY FDFNEEKLVN IAKTEAELGI 370 380 390 400 410 420 ELFVLDDGWF GKRDDDRRSL GDWIVNRRKL PNGLDGLAKQ VNELGMQFGL WVEPEMVSPN 430 440 450 460 470 480 SELYRKHPDW CLHVPNRPRS EGRNQLVLDY SREDVCDYII ETISNVLASA PITYVKWDMN 490 500 510 520 530 540 RHMTEIGSSA LPPERQRETA HRYMLGLYRV MDEMTSRFPH ILFESCSGGG GRFDPGMLYY 550 560 570 580 590 600 MPQTWTSDNT DAVSRLKIQY GTSLVYPISA MGAHVSAVPN HQVGRVASLK ARGHVAMSGN 610 620 630 640 650 660 FGYELDITKL TETEKQMIKQ QVAFYKDVRR LVQFGTFYRL LSPFEGNEAA WMFVSADRSE 670 680 690 700 710 720 ALVAYFRVLA EANAPLSYLR LKGLDPNQDY EIEGLGVYGG DELMYAGVAL PYRSGDFISM MWRLKAVQQ

References

[1]	"Elucidation of functional domains in thermostable isoenzymes of alpha-galactosidase in Bacillus stearothermophilus. Enzymatic properties are encoded in a genetically exchangeable domain." Janz L., Ganter C., Stezowski J., Mattes R. (In) Reuss M., Chmiel H., Gilles E-.D., Knackmuss H-.J. (eds.); BIOCHEMICAL ENGINEERING, STUTTGART, pp.170-173, Unknown Publisher (1991) Cited for: NUCLEOTIDE SEQUENCE. Strain: KVE39 EMBL AAG49421.1.
[2]	Watzlawick H., Ganter C., Mattes R. Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: KVE39 EMBL AAG49421.1.
[3]	"The molecular mechanism of thermostable ?-galactosidases AgaA and AgaB explained by x-ray crystallography and mutational studies." Merceron R., Foucault M., Haser R., Mattes R., Watzlawick H., Gouet P. J. Biol. Chem. 287:39642-39652(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AY013287 Genomic DNA. Translation: AAG49421.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4FNQ	X-ray	1.80	A	1-729	[»]

ProteinModelPortal

Q934H7.

ModBase

Search...

Protein family/group databases

CAZy

GH36. Glycoside Hydrolase Family 36.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

3.20.20.70. 1 hit.

InterPro

IPR013785. Aldolase_TIM.
IPR002252. Glyco_hydro_36.
IPR000111. Glyco_hydro_GHD.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

Pfam

PF02065. Melibiase. 1 hit.
[Graphical view]

PIRSF

PIRSF005536. Agal. 1 hit.

PRINTS

PR00743. GLHYDRLASE36.

SUPFAM

SSF51445. Glyco_hydro_cat. 1 hit.

PROSITE

PS00512. ALPHA_GALACTOSIDASE. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q934H7_GEOSE

Accession

Primary (citable) accession number: Q934H7

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)