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Protein
Submitted name:

ELRR (Extracellular Leucine-Rich Repeat) ONly

Gene

lron-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-CEL-193634. Axonal growth inhibition (RHOA activation).

Names & Taxonomyi

Protein namesi
Submitted name:
ELRR (Extracellular Leucine-Rich Repeat) ONlyImported
Gene namesi
Name:lron-1Imported
ORF Names:C44H4.1Imported, CELE_C44H4.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome X

Organism-specific databases

WormBaseiC44H4.1; CE44928; WBGene00008093; lron-1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei522 – 54625HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 607591Sequence analysisPRO_5004319406Add
BLAST

Proteomic databases

PaxDbiQ93377.
PRIDEiQ93377.

Interactioni

Protein-protein interaction databases

STRINGi6239.C44H4.1.

Structurei

3D structure databases

ProteinModelPortaliQ93377.
SMRiQ93377. Positions 26-506.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini431 – 48454LRRCTInterPro annotationAdd
BLAST

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00760000118777.
HOGENOMiHOG000018355.
InParanoidiQ93377.
OMAiTDSKLPH.
OrthoDBiEOG712TVW.
PhylomeDBiQ93377.

Family and domain databases

Gene3Di3.80.10.10. 3 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR026906. LRR_5.
[Graphical view]
PfamiPF00560. LRR_1. 1 hit.
PF13306. LRR_5. 1 hit.
PF13855. LRR_8. 3 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 10 hits.
SM00082. LRRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 2 hits.
PROSITEiPS51450. LRR. 13 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q93377-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLLFNLLI AGWVYSQCPT LQLQEPCTCT STRYEAVSIN CDGGSSLDAV
60 70 80 90 100
LESLSNSPQA IDSLTISNTP IEKMPGYAFQ GFQIKKLFLR NNGLRSFHPN
110 120 130 140 150
TFTGNLENSL EELEIRGNYI DGIPQSGVSI LKQLKILSLP DNLIEYVQDN
160 170 180 190 200
AFLSYHSRDS LLKLDLSANN LTAIHPTGLL GLENLSQLSL DKNLLSEIPS
210 220 230 240 250
QALENIPSLE DLSLGVNRIH TISRNSLPLP NLKSLSLEVN QIRLIPSDSF
260 270 280 290 300
SETPLLSYLY LGNNLLTSID ASMFLHIGGL KVLSMSNNKD ITSIQANGKL
310 320 330 340 350
SVQQFKLCIC ILAFQHAPSL IRLELFDCSI SRIEPKSLQK VQHIQVILLS
360 370 380 390 400
RNQITRISHD TFSNLPELSE LDLSGNSINA VDDFAFSQLP MLTSLDLSSN
410 420 430 440 450
RLESLPSNVI YDSLMQKKTS PVQRKLSIQN NPWRCDKDLM WLRKWLRDNG
460 470 480 490 500
DVTTAASNSP PAKCWTPSNL SGLDLRQTDS KLPHKTTKPP VDQFQYKNQQ
510 520 530 540 550
VTNSNGTSQL GYQNPHTEVN GLALVGLILG IVLVVFVSCI ILGYLMRFIF
560 570 580 590 600
LSYEAKTKPN VFGSTISSSG CIRNMYGGDG TLVSEDHGHP SSANNNVYLN

RPRHWWF
Length:607
Mass (Da):67,509
Last modified:July 13, 2010 - v4
Checksum:iC6CFF2B3BEBB3A87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB01867.4.
RefSeqiNP_510424.4. NM_078023.5.
UniGeneiCel.20169.

Genome annotation databases

EnsemblMetazoaiC44H4.1; C44H4.1; WBGene00008093.
GeneIDi181553.
KEGGicel:CELE_C44H4.1.
UCSCiC44H4.1. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284606 Genomic DNA. Translation: CAB01867.4.
RefSeqiNP_510424.4. NM_078023.5.
UniGeneiCel.20169.

3D structure databases

ProteinModelPortaliQ93377.
SMRiQ93377. Positions 26-506.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.C44H4.1.

Proteomic databases

PaxDbiQ93377.
PRIDEiQ93377.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC44H4.1; C44H4.1; WBGene00008093.
GeneIDi181553.
KEGGicel:CELE_C44H4.1.
UCSCiC44H4.1. c. elegans.

Organism-specific databases

CTDi181553.
WormBaseiC44H4.1; CE44928; WBGene00008093; lron-1.

Phylogenomic databases

eggNOGiKOG0619. Eukaryota.
COG4886. LUCA.
GeneTreeiENSGT00760000118777.
HOGENOMiHOG000018355.
InParanoidiQ93377.
OMAiTDSKLPH.
OrthoDBiEOG712TVW.
PhylomeDBiQ93377.

Enzyme and pathway databases

ReactomeiR-CEL-193634. Axonal growth inhibition (RHOA activation).

Family and domain databases

Gene3Di3.80.10.10. 3 hits.
InterProiIPR000483. Cys-rich_flank_reg_C.
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR003591. Leu-rich_rpt_typical-subtyp.
IPR026906. LRR_5.
[Graphical view]
PfamiPF00560. LRR_1. 1 hit.
PF13306. LRR_5. 1 hit.
PF13855. LRR_8. 3 hits.
[Graphical view]
SMARTiSM00369. LRR_TYP. 10 hits.
SM00082. LRRCT. 1 hit.
[Graphical view]
SUPFAMiSSF52058. SSF52058. 2 hits.
PROSITEiPS51450. LRR. 13 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    Caenorhabditis elegans Sequencing Consortium
    Sulson J.E., Waterston R.
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ93377_CAEEL
AccessioniPrimary (citable) accession number: Q93377
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: July 13, 2010
Last modified: June 8, 2016
This is version 115 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.