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Protein

Probable G-protein coupled receptor No18

Gene
N/A
Organism
Amphibalanus amphitrite (Striped barnacle) (Balanus amphitrite)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Probable G-protein coupled receptor for an amine.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor No18
OrganismiAmphibalanus amphitrite (Striped barnacle) (Balanus amphitrite)
Taxonomic identifieri1232801 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMaxillopodaCirripediaThoracicaSessiliaBalanidaeAmphibalanus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini5 – 36ExtracellularSequence analysisAdd BLAST32
Transmembranei37 – 58Helical; Name=1Sequence analysisAdd BLAST22
Topological domaini59 – 68CytoplasmicSequence analysis10
Transmembranei69 – 90Helical; Name=2Sequence analysisAdd BLAST22
Topological domaini91 – 107ExtracellularSequence analysisAdd BLAST17
Transmembranei108 – 128Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini129 – 148CytoplasmicSequence analysisAdd BLAST20
Transmembranei149 – 171Helical; Name=4Sequence analysisAdd BLAST23
Topological domaini172 – 196ExtracellularSequence analysisAdd BLAST25
Transmembranei197 – 218Helical; Name=5Sequence analysisAdd BLAST22
Topological domaini219 – 303CytoplasmicSequence analysisAdd BLAST85
Transmembranei304 – 325Helical; Name=6Sequence analysisAdd BLAST22
Topological domaini326 – 340ExtracellularSequence analysisAdd BLAST15
Transmembranei341 – 362Helical; Name=7Sequence analysisAdd BLAST22
Topological domaini363 – 375CytoplasmicSequence analysisAdd BLAST13

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000696601 – 379Probable G-protein coupled receptor No18Add BLAST379

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi17N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi105 ↔ 184PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ93127.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002002. Octopmn_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00664. OCTOPAMINER.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q93127-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGGEASITG RTAPELNASA APLDDERELG ETVAATALLL AIILVTIVGN
60 70 80 90 100
SLVIISVFTY RPLRSVQNFF VVSLAVADLT VALFVLPLNV AYRLLNQWLL
110 120 130 140 150
GSYLCQMWLT CDILCCTSSI LNLCVIALDR YWAITDPINY AQKRTIRRVN
160 170 180 190 200
TMIAAVWALS LVISVPPLLG WNDWPAQFTE DTPCTLTQER LFVVYSSSGS
210 220 230 240 250
FFIPLIIMSV VYAKIFFATK RRLRERTRKL GTLAVPAPPQ RTSSRPLAEL
260 270 280 290 300
ESVASQEDET EPSPEPEPLS SRADKPANGI SVHQFIEEKQ RISLSKERKA
310 320 330 340 350
ARVLGVIMGV FVVCWLPFFL MYAIVPFCTN CAPPSQRVVD FVTWLGYVNS
360 370
SLNPIIYTIY NKDFRTAFSR LLRCDRRMS
Length:379
Mass (Da):42,373
Last modified:February 1, 1997 - v1
Checksum:iDBD483758BA953C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83547 Genomic DNA. Translation: BAA12013.1.
PIRiJC6178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83547 Genomic DNA. Translation: BAA12013.1.
PIRiJC6178.

3D structure databases

ProteinModelPortaliQ93127.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002002. Octopmn_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00664. OCTOPAMINER.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGPR18_AMPAM
AccessioniPrimary (citable) accession number: Q93127
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.