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Protein

Probable G-protein coupled receptor No9

Gene
N/A
Organism
Amphibalanus amphitrite (Striped barnacle) (Balanus amphitrite)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Orphan G-protein coupled receptor.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei113 – 1131Implicated in ligand bindingBy similarity
Sitei208 – 2081Implicated in ligand bindingBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Recommended name:
Probable G-protein coupled receptor No9
OrganismiAmphibalanus amphitrite (Striped barnacle) (Balanus amphitrite)
Taxonomic identifieri1232801 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMaxillopodaCirripediaThoracicaSessiliaBalanidaeAmphibalanus

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3636ExtracellularSequence analysisAdd
BLAST
Transmembranei37 – 6024Helical; Name=1Sequence analysisAdd
BLAST
Topological domaini61 – 699CytoplasmicSequence analysis
Transmembranei70 – 9324Helical; Name=2Sequence analysisAdd
BLAST
Topological domaini94 – 10310ExtracellularSequence analysis
Transmembranei104 – 12724Helical; Name=3Sequence analysisAdd
BLAST
Topological domaini128 – 15225CytoplasmicSequence analysisAdd
BLAST
Transmembranei153 – 17220Helical; Name=4Sequence analysisAdd
BLAST
Topological domaini173 – 20028ExtracellularSequence analysisAdd
BLAST
Transmembranei201 – 22121Helical; Name=5Sequence analysisAdd
BLAST
Topological domaini222 – 375154CytoplasmicSequence analysisAdd
BLAST
Transmembranei376 – 39621Helical; Name=6Sequence analysisAdd
BLAST
Topological domaini397 – 40610ExtracellularSequence analysis
Transmembranei407 – 43024Helical; Name=7Sequence analysisAdd
BLAST
Topological domaini431 – 47646CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Probable G-protein coupled receptor No9PRO_0000069659Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi13 – 131N-linked (GlcNAc...)Sequence analysis
Glycosylationi17 – 171N-linked (GlcNAc...)Sequence analysis
Disulfide bondi106 ↔ 192PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ93126.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

InterProiIPR002233. ADR_fam.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01103. ADRENERGICR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q93126-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGPPLSPAP ADNVTLNVSC GRPATLFDWA DHRLISLLAL AFLNLMVVAG
60 70 80 90 100
NLLVVMAVFV HSKLRTVTNL FIVSLACADL LVGMLVLPFS ATLEVLDVWL
110 120 130 140 150
YGDVWCSVWL AVDVWMCTSS ILNLCAISLD RYLAVSQPIS YPSLMSTRRA
160 170 180 190 200
KQLIAAVWVL SFVICFPPLV GWNDRPGTLI GSRGSSACRL TCELTNERGY
210 220 230 240 250
VIYSALGSFF LPSTVMLFFY GRIYRTAVST TRAIAQGFRT TKEDEEGRLT
260 270 280 290 300
LRIHRGRSVT QRAEQAAAGG ARAHGQVRLT LSEPGARRQN KPSFVVHCRE
310 320 330 340 350
DSRAKNQYEI YTVVEGDSRP GRRVPQPQRP AKKLSSASQS SEDDSRPPRF
360 370 380 390 400
ISRVSRRNVR HQARRFRMET KAAKTVGIIV GLFILCWLPF FVCYLVRGFC
410 420 430 440 450
ADCVPPLLFS VFFWLGYCNS AVNPCVYALC SRDFRFAFSS ILCKCVCRRG
460 470
AMERRFRRTL LVGNRSQTEE DCEVAD
Length:476
Mass (Da):53,246
Last modified:February 1, 1997 - v1
Checksum:i0F55B51595D5CD06
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti454 – 4541R → A in BAA11424 (PubMed:8917082).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D78363 Genomic DNA. Translation: BAA11375.1.
D78587 Genomic DNA. Translation: BAA11424.1.
PIRiJC5042.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D78363 Genomic DNA. Translation: BAA11375.1.
D78587 Genomic DNA. Translation: BAA11424.1.
PIRiJC5042.

3D structure databases

ProteinModelPortaliQ93126.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR002233. ADR_fam.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01103. ADRENERGICR.
PR00237. GPCRRHODOPSN.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGPR9_AMPAM
AccessioniPrimary (citable) accession number: Q93126
Secondary accession number(s): Q93128
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 1, 1997
Last modified: May 11, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.