Q93118 (A16_ANOGA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein A16

Gene names

Name:	CTL3
ORF Names:	AGAP004810

Organism

Anopheles gambiae (African malaria mosquito)

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Anophelinae › Anopheles

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Tissue specificity	Expressed in the gut of adults. Ref.1
Developmental stage	Expressed during embryonic, larval and pupal stages. Highest expression is seen in late larval stages. Ref.1
Induction	Not induced by bacterial challenge in larvae. Ref.1
Sequence similarities	Contains 1 C-type lectin domain.

Ontologies

Keywords
Domain	Signal
Ligand	Lectin
PTM	Disulfide bond
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	sugar binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 192	170	Protein A16		PRO_0000017555
Regions
	Domain	71 – 186	116	C-type lectin
Amino acid modifications
	Disulfide bond	163 ↔ 177		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q93118 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: EFEA2CBD9B0824A0	FASTA	192	20,811
	10 20 30 40 50 60 MLLANTAAAV LLLIVCIGAS VGLPTVDEEN VVQAEQLPIL PTADSSKPTD DTVKAIAPQP 70 80 90 100 110 120 RYLLPADFAV KNKKFTIGTL GVGSFFRAWR NCIDEGKGLA TIESEKEQKY LESLLKASST 130 140 150 160 170 180 GSNYWIGATN IGASNTNKLT WITTDLPVQT KPPFLNVVAK STCIALTPTG SWTLRNCLNP 190 LNIFPYICEE YF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and characterization of differentially expressed cDNAs of the vector mosquito, Anopheles gambiae." Dimopoulos G.M., Richman A.M., della Torre A., Kafatos F.C., Louis C. Proc. Natl. Acad. Sci. U.S.A. 93:13066-13071(1996) [PubMed: 8917545] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, INDUCTION. Strain: G3. Tissue: Larva.
[2]	"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed: 12364791] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y08163 mRNA. Translation: CAA69355.1. AAAB01008968 Genomic DNA. Translation: EAA13236.4.
RefSeq	XP_317999.4. XM_317999.4.
3D structure databases
ProteinModelPortal	Q93118.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AGAP004810-RA; AGAP004810-PA; AGAP004810.
GeneID	1278414.
KEGG	aga:AgaP_AGAP004810.
VectorBase	AGAP004811. Anopheles gambiae.
Organism-specific databases
CTD	1278414.
Phylogenomic databases
GeneTree	EMGT00050000013519.
InParanoid	Q93118.
Family and domain databases
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR016187. C-type_lectin_fold. [Graphical view]
Gene3D	G3DSA:3.10.100.10. C-type_lectin-like. 1 hit.
Pfam	PF00059. Lectin_C. 1 hit. [Graphical view]
SMART	SM00034. CLECT. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit.
PROSITE	PS00615. C_TYPE_LECTIN_1. False negative. PS50041. C_TYPE_LECTIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A16_ANOGA

Accession

Primary (citable) accession number: Q93118
Secondary accession number(s): Q7Q2T9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	December 14, 2011
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)