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Reviewed, UniProtKB/Swiss-Prot Q930J0 (HIS83_RHIME)

Last modified February 9, 2010. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Histidinol-phosphate aminotransferase 3
    EC=2.6.1.9
Alternative name(s):
    Imidazole acetol-phosphate transaminase 3
Gene names
Name: hisC3
Ordered Locus Names: RA0206
ORF Names: SMa0387
Encoded onPlasmid pSymA (megaplasmid 1)
OrganismRhizobium meliloti (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier382 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length370 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 370370Histidinol-phosphate aminotransferase 3 HAMAP MF_01023
PRO_0000153437

Amino acid modifications

Modified residue2291N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q930J0-1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 81A868235F0EE332

FASTA37040,712
        10         20         30         40         50         60 
MAIPSRPIRE EIRSIAPYNA GLTLEEVRAK YHVDEVAKLS SNENPLGPSP ALRRLFPDIG 

        70         80         90        100        110        120 
ELARLYPDPQ GRALCARLAA SFDVENNQVI LGNGSEDLIA VICRSVVRAG DTVVTLYPSF 

       130        140        150        160        170        180 
PLHEDYTTLM GGKVDRVTVT PDLSVDMDAL LAAIARKPRM LMFSNPMNPV GSWLTPLQLA 

       190        200        210        220        230        240 
KVVAALDPET LIVVDEAYAE YAAGDDYPSA AEVLKVTGLN WVVLRTFSKA YGLAGLRIGY 

       250        260        270        280        290        300 
GIVSDGSLCD FFNRARTPFN TNAIAQVSAL AAFDDTYHLN RSVELALVER ERMKKELATM 

       310        320        330        340        350        360 
GYRIAPSKCN FLFFDARTEA TPVAEALLRR GVIVKPWKQP RFETYIRVSI GSPVENDHFI 

       370 
HALKEVEAVG 

« Hide

References

[1]"Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid."
Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F., Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L., Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H. expand/collapse author list , Palm C., Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A., Long S.R.
Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001) [PubMed: 11481432] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1021.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006469 Genomic DNA. Translation: AAK64864.1.
PIRF95287.
RefSeqNP_435452.1.

3D structure databases

SMRQ930J0. Positions 6-366.
ModBaseSearch...

Genome annotation databases

GeneID1235431.
GenomeReviewsGene locus RA0206 in contig AE006469_GR.
KEGGsme:SMa0387.
NMPDRfig|266834.1.peg.206.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646350.
OMASFPLHED.

Enzyme and pathway databases

BioCycSMEL266834:SMA0387-MONOMER.
BRENDA2.6.1.9. 142.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR01141. hisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHIS83_RHIME
AccessionPrimary (citable) accession number: Q930J0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: December 1, 2001
Last modified: February 9, 2010
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents