Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Truncated lysosomal acid alpha-mannosidase

Gene

MANB

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Protein family/group databases

CAZyiGH38. Glycoside Hydrolase Family 38.

Names & Taxonomyi

Protein namesi
Submitted name:
Truncated lysosomal acid alpha-mannosidaseImported (EC:3.2.1.24Imported)
Gene namesi
Name:MANBImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500431938427 – 323Sequence analysisAdd BLAST297

Proteomic databases

PaxDbiQ93093.
PeptideAtlasiQ93093.
PRIDEiQ93093.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000395473.

Structurei

3D structure databases

ProteinModelPortaliQ93093.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 319Glyco_hydro_38InterPro annotationAdd BLAST279

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1959. Eukaryota.
ENOG410XQMZ. LUCA.
HOGENOMiHOG000007676.

Family and domain databases

Gene3Di3.20.110.10. 1 hit.
InterProiIPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR027291. Glyco_hydro_38/57_N.
IPR000602. Glyco_hydro_38_N.
[Graphical view]
PfamiPF01074. Glyco_hydro_38. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.

Sequencei

Sequence statusi: Complete.

Q93093-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRALRPPLP PLCFFLLLLA AAGARAGGYE TCPTVQPNML NVHLLPHTHD
60 70 80 90 100
DVGWLKTVDQ YFYGIKNDIQ HAGVQYILDS VISALLEDPT RRFIYVEIAF
110 120 130 140 150
FSRWWHQQTN ATQEVVRDLV RQGRLEFANG GWVMNDEAAT HYGAIVDQMT
160 170 180 190 200
LGLRFLEDTF GNDGRPRVAW HIDPFGHSRE QASLFAQMGF DGFFFGRLDY
210 220 230 240 250
QDKWVRMQKL EMEQVWRAST SLKPPTADLF TGVLPNGYNP PRNLCWDVLC
260 270 280 290 300
VDQPLVEDPR SPEYNAKELV DYFLNVATAQ GRYYRTNHTV MTMGSDFQYE
310 320
NANMWFKNLD KLIRLVNAQV SET
Length:323
Mass (Da):37,152
Last modified:February 1, 1997 - v1
Checksum:i4BC97F324142E540
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68382 mRNA. Translation: AAC50811.1.
UniGeneiHs.356769.
Hs.657204.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U68382 mRNA. Translation: AAC50811.1.
UniGeneiHs.356769.
Hs.657204.

3D structure databases

ProteinModelPortaliQ93093.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000395473.

Protein family/group databases

CAZyiGH38. Glycoside Hydrolase Family 38.

Proteomic databases

PaxDbiQ93093.
PeptideAtlasiQ93093.
PRIDEiQ93093.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1959. Eukaryota.
ENOG410XQMZ. LUCA.
HOGENOMiHOG000007676.

Miscellaneous databases

ChiTaRSiMAN2B1. human.

Family and domain databases

Gene3Di3.20.110.10. 1 hit.
InterProiIPR011330. Glyco_hydro/deAcase_b/a-brl.
IPR027291. Glyco_hydro_38/57_N.
IPR000602. Glyco_hydro_38_N.
[Graphical view]
PfamiPF01074. Glyco_hydro_38. 1 hit.
[Graphical view]
SUPFAMiSSF88713. SSF88713. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ93093_HUMAN
AccessioniPrimary (citable) accession number: Q93093
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: July 6, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.