Q92YD2 (BETB2_RHIME) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 74.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Betaine aldehyde dehydrogenase 2 Short name=BADH 2 EC=1.2.1.8 | ||||||
| Gene names |
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| Encoded on | Plasmid pSymA (megaplasmid 1) | ||||||
| Organism | Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 266834 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › ![]() |
Protein attributes
| Sequence length | 481 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP-Rule MF_00804 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP-Rule MF_00804 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. |
| Sequence caution | The sequence AAK65610.1 differs from that shown. Reason: Erroneous initiation. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome Plasmid |
| Gene Ontology (GO) | |
| Biological_process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: HAMAP |
| Molecular_function | betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 481 | 481 | Betaine aldehyde dehydrogenase 2 HAMAP-Rule MF_00804 | PRO_0000056554 | |||||
Regions | |||||||||
| Nucleotide binding | 230 – 235 | 6 | NAD By similarity | ||||||
Sites | |||||||||
| Active site | 252 | 1 | By similarity | ||||||
| Active site | 286 | 1 | By similarity | ||||||
Sequences
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References
| [1] | "Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid." Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F., Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L., Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H. Long S.R.Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021. |
| [2] | "The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. Batut J.Science 293:668-672(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE006469 Genomic DNA. Translation: AAK65610.1. Different initiation. |
| PIR | H95380. |
| RefSeq | NP_436198.1. NC_003037.1. |
3D structure databases | |
| ProteinModelPortal | Q92YD2. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 266834.SMa1731. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AAK65610; AAK65610; SMa1731. |
| GeneID | 1235988. |
| KEGG | sme:SMa1731. |
| PATRIC | 23628404. VBISinMel96828_0981. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1012. |
| HOGENOM | HOG000271505. |
| KO | K00130. |
| ProtClustDB | PRK13252. |
Enzyme and pathway databases | |
| BioCyc | SMEL266834:GJF6-5958-MONOMER. |
| UniPathway | UPA00529; UER00386. |
Family and domain databases | |
| Gene3D | 3.40.309.10. 1 hit. 3.40.605.10. 1 hit. |
| HAMAP | MF_00804. BADH. |
| InterPro | IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR011264. Betaine_Ald_DH. [Graphical view] |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| SUPFAM | SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BETB2_RHIME | ||||||||
| Accession | Primary (citable) accession number: Q92YD2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Recent format changes Overview of recent format changes |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
