Q92UV8 (Q92UV8_RHIME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Probable phosphonoacetate hydrolase EMBL CAC49378.1
EC=3.6.1.9 EMBL CAC49378.1

Gene names

Name:	phnA EMBL CAC49378.1
ORF Names:	SM_b21538 EMBL CAC49378.1

Encoded on

Plasmid pSymB EMBL CAC49378.1

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP] EMBL CAC49378.1

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Rhizobium meliloti

Protein attributes

Sequence length	424 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Hydrolase EMBL CAC49378.1
Technical term	3D-structure PDB 3SZY PDB 3SZZ PDB 3T00 PDB 3T01 PDB 3T02 Complete proteome Plasmid EMBL CAC49378.1
Gene Ontology (GO)
Molecular_function	NADH pyrophosphatase activity Inferred from electronic annotation. Source: EC phosphonoacetate hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q92UV8 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: A11E392B00AE040A	FASTA	424	46,256
	10 20 30 40 50 60 MNQMSKISVT VNGRRYPWPR VPAIAVCLDG CEPAYLDAAI DAGLMPALKR IKERGAVRLA 70 80 90 100 110 120 HSVIPSFTNP NNLSIATGSP PAVHGICGNY LYEPSTGEEV MMNDPKFLRA PTIFQAFYDA 130 140 150 160 170 180 GARVAVVTAK DKLRALLGKG LRFDEGRAVC FSSEKSDKAT RAEHGIDNAS AWLGRPVPEV 190 200 210 220 230 240 YSAALSEFVF AAGVKLLREF RPDIMYLTTT DYVQHKYAPG VPEANSFYEM FDRYLAELDG 250 260 270 280 290 300 LGAAIVVTAD HGMKPKHKAD GSPDVIYVQD LLDEWLGKDA ARVILPITDP YVVHHGALGS 310 320 330 340 350 360 FATAYLPDGC DRSEIMARLK AIQGVDVVLG REEACRRFEL PEDRIGDIVL VSSENKTLGT 370 380 390 400 410 420 SEHRHDLAAL DEPLRSHGGL TEQEVPFIVN RVLPELPNAP RLRNFDAFFY AVTAAAEAGA EGGL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti." Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J., Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A. Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021 EMBL CAC49378.1.
[2]	"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J. Science 293:668-672(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[3]	"Structural and mechanistic insights into C-P bond hydrolysis by phosphonoacetate hydrolase." Agarwal V., Borisova S.A., Metcalf W.W., van der Donk W.A., Nair S.K. Chem. Biol. 18:1230-1240(2011) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL591985 Genomic DNA. Translation: CAC49378.1.

PIR

B95964.

RefSeq

NP_437518.1. NC_003078.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3SZY	X-ray	1.35	A	1-424	[»]
3SZZ	X-ray	2.00	A	1-424	[»]
3T00	X-ray	1.80	A	1-424	[»]
3T01	X-ray	1.60	A	1-424	[»]
3T02	X-ray	2.00	A	1-424	[»]

ProteinModelPortal

Q92UV8.

SMR

Q92UV8. Positions 9-411.

ModBase

Search...

Protein-protein interaction databases

STRING

266834.SM_b21538.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

CAC49378; CAC49378; SM_b21538.

GeneID

1237309.

KEGG

sme:SM_b21538.

PATRIC

23638368. VBISinMel96828_5905.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

HOG000218962.

OMA

PTVVVCV.

ProtClustDB

CLSK892258.

Enzyme and pathway databases

BioCyc

MetaCyc:MONOMER-16712.
SMEL266834:GJF6-4411-MONOMER.

Family and domain databases

Gene3D

3.40.720.10. 1 hit.

InterPro

IPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR024873. E-NPP.
IPR002591. Phosphodiest/P_Trfase.
IPR012710. Phosphonoacetate_hydro.
[Graphical view]

PANTHER

PTHR10151. PTHR10151. 1 hit.

Pfam

PF01663. Phosphodiest. 1 hit.
[Graphical view]

SUPFAM

SSF53649. Alkaline_phosphatase_core. 1 hit.

TIGRFAMs

TIGR02335. hydr_PhnA. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q92UV8.

Entry information

Entry name

Q92UV8_RHIME

Accession

Primary (citable) accession number: Q92UV8

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)