Q92UI1 (G6PI2_RHIME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative glucose-6-phosphate isomerase 2
Short name=GPI 2
EC=5.3.1.9

Alternative name(s):
Phosphoglucose isomerase 2
Short name=PGI 2
Phosphohexose isomerase 2
Short name=PHI 2

Gene names

Name:	pgiA2
Ordered Locus Names:	RB1150
ORF Names:	SMb20857

Encoded on

Plasmid pSymB (megaplasmid 2)

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_01410
Cofactor	Binds 1 iron ion per subunit By similarity. HAMAP MF_01410
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_01410
Subunit structure	Homodimer By similarity. HAMAP MF_01410
Subcellular location	Cytoplasm By similarity HAMAP MF_01410.
Miscellaneous	R.meliloti has a classic glucose-6-phosphate isomerase (AC Q92SC4) and two archaeal-type glucose-6-phosphate isomerases. HAMAP MF_01410
Sequence similarities	Belongs to the archaeal-type GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Ligand	Iron Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: EC iron ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 200	200	Putative glucose-6-phosphate isomerase 2 HAMAP MF_01410		PRO_0000185362
Sites
	Metal binding	92	1	Iron By similarity
	Metal binding	94	1	Iron By similarity
	Metal binding	101	1	Iron By similarity
	Metal binding	140	1	Iron By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q92UI1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 7D397D5ADC890AD3	FASTA	200	22,063
	10 20 30 40 50 60 MLILFEPGVC QVDVATGRLK GATNRYVKTF RDLAGLYRDE SAYQALIATR GDDVAYEVTD 70 80 90 100 110 120 YKPSANGGDI IIGVTRMEPG KIGDEYFMTR GHIHARPNRP EMYYGEAGVG VMLLESPHGE 130 140 150 160 170 180 IRTIEMRART MCYVPPFWIH RSVNVGLEPL VMTFSYPADA GQDYDVIAKA GGMRTVLSMT 190 200 GTVDGPQSIT PVIQGDTHRL

References

[1]

"The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti." Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J., Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A. Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001) [PubMed: 11481431] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.

[2]

"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J. Science 293:668-672(2001) [PubMed: 11474104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591985 Genomic DNA. Translation: CAC49550.1.
PIR	F95985.
RefSeq	NP_437690.1. NC_003078.1.
3D structure databases
ProteinModelPortal	Q92UI1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1237481.
GenomeReviews	Gene locus RB1150 in contig AL591985_GR.
KEGG	sme:SM_b20857.
NMPDR	fig|266834.1.peg.5785.
PATRIC	23638716. VBISinMel96828_6079.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG725476.
OMA	RWIEMER.
ProtClustDB	PRK04190.
Enzyme and pathway databases
BioCyc	SMEL266834:SMB20857-MONOMER.
Family and domain databases
HAMAP	MF_01410. G6P_isomerase_arch. [Tree]
InterPro	IPR011051. Cupin_RmlC_type. IPR010551. G6P_isomerase_prok. IPR016758. G6P_isomerase_subgr. IPR014710. RmlC-like_jellyroll. [Graphical view]
Gene3D	G3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit.
KO	K06859.
Pfam	PF06560. GPI. 1 hit. [Graphical view]
PIRSF	PIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G6PI2_RHIME

Accession

Primary (citable) accession number: Q92UI1

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2002
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program