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Q92UI1 (G6PI2_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative glucose-6-phosphate isomerase 2

Short name=GPI 2
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 2
Short name=PGI 2
Phosphohexose isomerase 2
Short name=PHI 2
Gene names
Name:pgiA2
Ordered Locus Names:RB1150
ORF Names:SMb20857
Encoded onPlasmid pSymB (megaplasmid 2)
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_01410

Cofactor

Binds 1 iron ion per subunit By similarity. HAMAP-Rule MF_01410

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_01410

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01410

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01410.

Miscellaneous

R.meliloti has a classic glucose-6-phosphate isomerase (AC Q92SC4) and two archaeal-type glucose-6-phosphate isomerases.

Sequence similarities

Belongs to the archaeal-type GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   LigandIron
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Plasmid
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

iron ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 200200Putative glucose-6-phosphate isomerase 2 HAMAP-Rule MF_01410
PRO_0000185362

Sites

Metal binding921Iron By similarity
Metal binding941Iron By similarity
Metal binding1011Iron By similarity
Metal binding1401Iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92UI1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 7D397D5ADC890AD3

FASTA20022,063
        10         20         30         40         50         60 
MLILFEPGVC QVDVATGRLK GATNRYVKTF RDLAGLYRDE SAYQALIATR GDDVAYEVTD 

        70         80         90        100        110        120 
YKPSANGGDI IIGVTRMEPG KIGDEYFMTR GHIHARPNRP EMYYGEAGVG VMLLESPHGE 

       130        140        150        160        170        180 
IRTIEMRART MCYVPPFWIH RSVNVGLEPL VMTFSYPADA GQDYDVIAKA GGMRTVLSMT 

       190        200 
GTVDGPQSIT PVIQGDTHRL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591985 Genomic DNA. Translation: CAC49550.1.
PIRF95985.
RefSeqNP_437690.1. NC_003078.1.

3D structure databases

ProteinModelPortalQ92UI1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266834.SM_b20857.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC49550; CAC49550; SM_b20857.
GeneID1237481.
KEGGsme:SM_b20857.
PATRIC23638716. VBISinMel96828_6079.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2140.
KOK06859.
OMAEYFMTRG.
OrthoDBEOG6M6JRR.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-4583-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D2.60.120.10. 1 hit.
HAMAPMF_01410. G6P_isomerase_arch.
InterProIPR010551. G6P_isomerase_prok.
IPR016758. G6P_isomerase_subgr.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamPF06560. GPI. 1 hit.
[Graphical view]
PIRSFPIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
SUPFAMSSF51182. SSF51182. 1 hit.
ProtoNetSearch...

Entry information

Entry nameG6PI2_RHIME
AccessionPrimary (citable) accession number: Q92UI1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: December 1, 2001
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways