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Q92TA4 (MASZ_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Malate synthase G
EC=2.3.3.9
Gene names
Name:glcB
Ordered Locus Names:R00062
ORF Names:SMc02581
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium ›

Protein attributes

Sequence length723 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. HAMAP-Rule MF_00641

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. HAMAP-Rule MF_00641

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the malate synthase family. GlcB subfamily.

Ontologies

Keywords
   Biological processGlyoxylate bypass
Tricarboxylic acid cycle
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 723723Malate synthase G HAMAP-Rule MF_00641
PRO_0000166898

Sites

Active site3381Proton acceptor By similarity
Active site6291Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92TA4 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: A0E95E8A5164BB58

FASTA72378,854
        10         20         30         40         50         60 
MDRVEKYGLQ IDAGLHRFLV EEAMPGTGVD ADRFFSAFSD LVHDLGPKNR ALLVKRDELQ 

        70         80         90        100        110        120 
ARLDGWYREH GAPVDMEAYE AFLREIGYLL PEGPDFYVST ANVDSEIATI AGPQLVVPVM 

       130        140        150        160        170        180 
NARYALNAAN ARWGSLYDAL YGTDAIAETD GAERGKGYNP KRGAKVIAWA REFLDASAPL 

       190        200        210        220        230        240 
AAGRWSDAKS FSVEGATLTV TLADGTKSAP RNSVQFAGYA GDPAAPSEIV LRRNGLHIVI 

       250        260        270        280        290        300 
VLDATTPIGK ADAAGISDVV LESAITTIMD CEDSIAAVDA EDKVLVYRNW LGLMKGDLEE 

       310        320        330        340        350        360 
EVTKGGRAFT RRLNPDRAYT APDGATLTLP GRSLMLVRNV GHLMTNPAVL DRDGEEVPEG 

       370        380        390        400        410        420 
LMDAMVTALI ALHDIGRNGR RANSRSGSMY VVKPKMHGPE EVAFACEIFA RVEAALGLPA 

       430        440        450        460        470        480 
NAMKMGIMDE ERRTTVNLKE CIRAARERVV FINTGFLDRT GDEIHTSMEA GPMIRKGDMK 

       490        500        510        520        530        540 
QAPWISAYEN WNVDVGLECG LSGHAQIGKG MWAMPDLMAA MLEQKIVHPK AGANTAWVPS 

       550        560        570        580        590        600 
PTAATLHATH YHRVNVAEVQ ASLKSRTRAK LADILSVPVA ARPNWTEEEI QRELDNNAQG 

       610        620        630        640        650        660 
ILGYVVRWVD QGVGCSKVPD INNVGLMEDR ATLRISAQHM ANWLHHGIVS EAQIVETMQR 

       670        680        690        700        710        720 
MAAIVDGQNA GDPNYQPMAG RFEESIAFQA ALDLVLKGRE QPNGYTEPVL HRRRLELKAK 


QGA

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL591688 Genomic DNA. Translation: CAC41449.1.
RefSeqNP_384168.1. NC_003047.1.

3D structure databases

ProteinModelPortalQ92TA4.
SMRQ92TA4. Positions 2-720.
ModBaseSearch...

Protein-protein interaction databases

STRING266834.SMc02581.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC41449; CAC41449; SMc02581.
GeneID1231687.
KEGGsme:SMc02581.
PATRIC23629277. VBISinMel96828_1416.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2225.
HOGENOMHOG000220740.
KOK01638.
OMAVVKPKMH.
ProtClustDBPRK02999.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-62-MONOMER.
UniPathwayUPA00703; UER00720.

Family and domain databases

Gene3D2.170.170.11. 2 hits.
HAMAPMF_00641. Malate_synth_G.
InterProIPR011076. Malate_synth-like.
IPR023310. Malate_synth_G_beta_sub_dom.
IPR001465. Malate_synthase.
IPR006253. Malate_synthG.
[Graphical view]
PANTHERPTHR21631:SF1. PTHR21631:SF1. 1 hit.
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
SUPFAMSSF51645. Malat_synth_like. 1 hit.
TIGRFAMsTIGR01345. malate_syn_G. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMASZ_RHIME
AccessionPrimary (citable) accession number: Q92TA4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 30, 2003
Last sequence update: December 1, 2001
Last modified: May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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