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Q92SF4

- RNPA_RHIME

UniProt

Q92SF4 - RNPA_RHIME

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Protein
Ribonuclease P protein component
Gene
rnpA, R00445, SMc01720
Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciSMEL266834:GJF6-456-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component (EC:3.1.26.5)
Short name:
RNase P protein
Short name:
RNaseP protein
Alternative name(s):
Protein C5
Gene namesi
Name:rnpA
Ordered Locus Names:R00445
ORF Names:SMc01720
OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Taxonomic identifieri266834 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
ProteomesiUP000001976: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 128128Ribonuclease P protein componentUniRule annotation
PRO_0000198515Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Protein-protein interaction databases

STRINGi266834.SMc01720.

Structurei

3D structure databases

ProteinModelPortaliQ92SF4.

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.

Phylogenomic databases

eggNOGiCOG0594.
HOGENOMiHOG000266302.
KOiK03536.
OMAiPGNDYVI.
OrthoDBiEOG6T4S2H.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomiPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92SF4-1 [UniParc]FASTAAdd to Basket

« Hide

MTTDKDKMAV GRLKSRPQFL AVRAGESRRG PLFLLEVLDR NDPEGEARVG    50
FTVTKKHGNA VERNRMRRRL KEAVRLSAGF AMKPGHDYVI VARRDLLNAP 100
FDALTRALRD RIENKPKQKR PPAGSRKS 128
Length:128
Mass (Da):14,533
Last modified:December 1, 2001 - v1
Checksum:i8D801E09E5216E13
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL591688 Genomic DNA. Translation: CAC41882.1.
RefSeqiNP_384551.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaiCAC41882; CAC41882; SMc01720.
GeneIDi1232079.
KEGGisme:SMc01720.
PATRICi23630101. VBISinMel96828_1820.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL591688 Genomic DNA. Translation: CAC41882.1 .
RefSeqi NP_384551.1. NC_003047.1.

3D structure databases

ProteinModelPortali Q92SF4.
ModBasei Search...

Protein-protein interaction databases

STRINGi 266834.SMc01720.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC41882 ; CAC41882 ; SMc01720 .
GeneIDi 1232079.
KEGGi sme:SMc01720.
PATRICi 23630101. VBISinMel96828_1820.

Phylogenomic databases

eggNOGi COG0594.
HOGENOMi HOG000266302.
KOi K03536.
OMAi PGNDYVI.
OrthoDBi EOG6T4S2H.

Enzyme and pathway databases

BioCyci SMEL266834:GJF6-456-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
ProDomi PD003629. Ribonuclease_P. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SUPFAMi SSF54211. SSF54211. 1 hit.
TIGRFAMsi TIGR00188. rnpA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1021.

Entry informationi

Entry nameiRNPA_RHIME
AccessioniPrimary (citable) accession number: Q92SF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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