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Q92SC4 (G6PI_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:R00483
ORF Names:SMc02163
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length541 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 541541Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180719

Sites

Active site3461Proton donor By similarity
Active site3771 By similarity
Active site5061 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92SC4 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 79F112BE8F9F57A0

FASTA54158,611
        10         20         30         40         50         60 
MKALVENLKA TARETDATDI RAAFAADPNR FSRFSTAFDD LLFDYSKCAV NDRIIDGLEA 

        70         80         90        100        110        120 
LAKAAKVEEK RDAMFRGDII NITEERAVLH TALRNRSNRP VLVDGKDVMP DVNAVLEAMG 

       130        140        150        160        170        180 
KFADDIRSGA LKGATGKKIT DVVNIGIGGS DLGPVMATLA LAPFHDGPRL HFVSNVDGAH 

       190        200        210        220        230        240 
IADTLTLLDP ETSLFIVASK TFTTIETMTN AATARAFIAG KLGEAAVGHH FAAVSTALDK 

       250        260        270        280        290        300 
VGAFGIDAAR VFGFWDWVGG RYSIWSAIGL PLMIAIGKEN FGRFLDGGHA IDEHFRSAPL 

       310        320        330        340        350        360 
RQNIPMLLGL IGFYNRNVLG YPSRAILPYD QRLTRFPAYL QQLDMESNGK GVTLDSQPVE 

       370        380        390        400        410        420 
FSTGPVVWGE PGTNGQHAFY QLIHQGTDVI PAEFMIAANG HEKDLRHQHQ LLMANCLAQS 

       430        440        450        460        470        480 
EALMKGRTLA EAKAQLTSKG MDDAKADKIA PHRVFTGNRP SLTIVYDQLD PFALGRLIAL 

       490        500        510        520        530        540 
YEHRVFVEGA LFNINSFDQW GVELGKELAT GLLPVIEGKE SAEGHDSSTA GLVAALLKAA 


R 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591688 Genomic DNA. Translation: CAC41920.1.
RefSeqNP_384589.1. NC_003047.1.

3D structure databases

ProteinModelPortalQ92SC4.
SMRQ92SC4. Positions 15-538.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266834.SMc02163.

Proteomic databases

ProMEXQ92SC4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC41920; CAC41920; SMc02163.
GeneID1232118.
KEGGsme:SMc02163.
PATRIC23630183. VBISinMel96828_1860.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261370.
KOK01810.
OMANCHFVAN.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-495-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_RHIME
AccessionPrimary (citable) accession number: Q92SC4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: December 1, 2001
Last modified: June 11, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways