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Q92S49 (PNCB_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:R00580
ORF Names:SMc02276
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_0000205842

Sequences

Sequence LengthMass (Da)Tools
Q92S49 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 34241F979F793723

FASTA43449,735
        10         20         30         40         50         60 
MPKTDIARRV YNHTWKLDPI VRSLLDTDFY KLLMLQMIWQ LYPDVDATFS LINRTKTVRL 

        70         80         90        100        110        120 
ADEIDEQELR DQLDHARGLR FTKKEMIWLA GNSFYGRTQI FSPEFLAWLA RFRLPEYELS 

       130        140        150        160        170        180 
RRDGQFELTF RGRWAETTMW EIPALAIINE LRSRAAMKGL GPFTLDVLYA RAKAKMWSKV 

       190        200        210        220        230        240 
EQLREHPNLR ISDFGTRRRH SFLWQRWCVE ALKEGIGSSF TGSSNVLLAM DNDLEAVGTN 

       250        260        270        280        290        300 
AHELPMVAAA LTRNDRELAA APYKVLQDWN QLYGGNLLIV LPDAFGTAAF LRDAPDWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIEGGEKIIA WWKKMGRDPR EKLLIFSDGL DVDTIIRTYC HFEGRVRMSF 

       370        380        390        400        410        420 
GWGTNLTNDF AGCAPTEING LNPISIVCKV SEANGRPAVK LSDNPRKATG DPAEVERYLK 

       430 
FFGSEDFVEQ SVRV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591688 Genomic DNA. Translation: CAC45152.1.
RefSeqNP_384686.1. NC_003047.1.

3D structure databases

ProteinModelPortalQ92S49.
SMRQ92S49. Positions 1-426.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266834.SMc02276.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC45152; CAC45152; SMc02276.
GeneID1232217.
KEGGsme:SMc02276.
PATRIC23630379. VBISinMel96828_1957.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-594-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_RHIME
AccessionPrimary (citable) accession number: Q92S49
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: December 1, 2001
Last modified: March 19, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways