Q92RG6 (COXZ_RHIME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cytochrome c oxidase assembly protein CtaG

Gene names

Name:	ctaG
Ordered Locus Names:	R00908
ORF Names:	SMc00012

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I By similarity. HAMAP MF_00155
Subcellular location	Cell inner membrane; Single-pass type II membrane protein; Periplasmic side Potential HAMAP MF_00155.
Sequence similarities	Belongs to the COX11/CtaG family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Ligand	Copper
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	copper ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 198

198

Cytochrome c oxidase assembly protein CtaG HAMAP MF_00155

PRO_0000206039

Regions

Topological domain

1 – 12

12

Cytoplasmic Potential

Transmembrane

13 – 35

23

Helical; Signal-anchor for type II membrane protein; Potential

Topological domain

36 – 198

163

Periplasmic Potential

Secondary structure

1

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198

Helix Strand Turn

Details...

Beta strand

59 – 61

3

Beta strand

67 – 75

9

Beta strand

81 – 84

4

Beta strand

88 – 92

5

Beta strand

100 – 106

7

Beta strand

108 – 110

3

Beta strand

117 – 120

4

Beta strand

122 – 124

3

Beta strand

147 – 152

6

Helix

158 – 161

4

Turn

164 – 168

5

Beta strand

174 – 178

5

Sequences

	Sequence		Length	Mass (Da)
	Q92RG6 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: B4D9CBB4079DD0DE	FASTA	198	21,812
	10 20 30 40 50 60 MADNGQADRK ERSNGVIVGT CLAFVAGMIG MAYAAVPLYD MFCRVTGYNG TTQRVEQASD 70 80 90 100 110 120 LILDEKIKVT FDANVAAGLP WEFVPVQRDI DVRIGETVQI MYRAKNLAST PTTGQATFNV 130 140 150 160 170 180 TPMAAGAYFN KVQCFCFTET TLEPGEEMEM PVVFFVDPEI VKPVETQGIK TLTLSYTFYP 190 REPSKPVAQV KAKAENKL

References

[1]	"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021." Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F. Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed: 11481430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[2]	"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J. Science 293:668-672(2001) [PubMed: 11474104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AL591688 Genomic DNA. Translation: CAC45480.1.

RefSeq

NP_385014.1. NC_003047.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1SO9	NMR	-	A	36-198	[»]
1SP0	NMR	-	A	36-198	[»]

ProteinModelPortal

Q92RG6.

SMR

Q92RG6. Positions 55-185.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1232549.

GenomeReviews

Gene locus R00908 in contig AL591688_GR.

KEGG

sme:SMc00012.

NMPDR

fig|266834.1.peg.2202.

PATRIC

23631083. VBISinMel96828_2305.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

HBG525908.

OMA

KLIFYRA.

ProtClustDB

PRK05089.

Enzyme and pathway databases

BioCyc

SMEL266834:SMC00012-MONOMER.

Family and domain databases

HAMAP

MF_00155. CtaG.
[Tree]

InterPro

IPR023471. CtaG/Cox11_dom.
IPR007533. Cyt_c_oxidase_assmbl_CtaG.
[Graphical view]

Gene3D

G3DSA:2.60.370.10. CtaG_Cox11. 1 hit.

KO

K02258.

PANTHER

PTHR21320. CtaG_Cox11. 1 hit.

Pfam

PF04442. CtaG_Cox11. 1 hit.
[Graphical view]

PIRSF

PIRSF005413. COX11. 1 hit.

SUPFAM

SSF110111. CtaG_Cox11. 1 hit.

ProtoNet

Search...

Entry information

Entry name

COXZ_RHIME

Accession

Primary (citable) accession number: Q92RG6

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program