Elongation factor G - Rhizobium meliloti (strain 1021) (Ensifer meliloti)

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Q92QH2 (EFG_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 64. History...

Clusters with 100%, 90%, 50% identity |

Documents (1) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
Elongation factor G
Short name=EF-G

Gene names

Name:	fusA
Synonyms:	fusA1
Ordered Locus Names:	R01353
ORF Names:	SMc01312

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	699 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome By similarity. HAMAP MF_00054_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00054_B.
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	GTP-binding Nucleotide-binding
Molecular function	Elongation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 699

699

Elongation factor G HAMAP MF_00054_B

PRO_0000091192

Regions

Nucleotide binding

17 – 24

GTP By similarity

Nucleotide binding

86 – 90

GTP By similarity

Nucleotide binding

140 – 143

GTP By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q92QH2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 55AF7B8ADFE90FAB
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FASTA

699

77,808

        10         20         30         40         50         60 
MAREYKIEDY RNFGIMAHID AGKTTTTERI LYYTGKSHKI GEVHDGAATM DWMEQEQERG 

        70         80         90        100        110        120 
ITITSAATTT FWKGRDGKTR RFNIIDTPGH VDFTIEVERS LRVLDGAIAL LDANAGVEPQ 

       130        140        150        160        170        180 
TETVWRQAEK YHVPRMIFCN KMDKTGADFY RSVEMIKMRL GATAVVMQLP IGAESDFKGV 

       190        200        210        220        230        240 
IDLIEMNALV WRDESLGAQW DVVEIPADMK EKAEEYREKL IETVVEIDEA AMEAYLEGTY 

       250        260        270        280        290        300 
PDNDKIRELV RRGTIDVKFH PMFCGTAFKN KGVQPLLDAV VDYLPSPIDI PAIKGIDVKT 

       310        320        330        340        350        360 
EGEITRKADD NEPLSMLAFK IMNDPFVGSL TFARIYSGKL EKGTSVMNTV KEKRERVGRM 

       370        380        390        400        410        420 
LQMHSNSRED IEEAFAGDIV ALAGLKETTT GDTLCDPLKP VILERMEFPE PVIQIAIEPK 

       430        440        450        460        470        480 
TKGDQEKMGL ALNRLAAEDP SFRVKTDEES GQTIIAGMGE LHLDIIVDRM RREFKVEASV 

       490        500        510        520        530        540 
GAPQVAYRET ITRKHEEDYT HKKQSGGTGQ FARVKIVFEP NPEGEDFAFE SKIVGGAVPK 

       550        560        570        580        590        600 
EYIPGVQKGI ESVLSSGPLA GFPMLGVKAT LIDGAFHDVD SSVLAFEIAS RACFREAAKK 

       610        620        630        640        650        660 
AGAQLLEPIM KVEVVTPEDY VGDVIGDLNS RRGQIQGQEA RGVAVVINAH VPLANMFKYV 

       670        680        690 
DNLRSMSQGR AQYTMLFDHY APVPSNVAQE IQAKYSGQK

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References

[1]	"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021." Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. Galibert F. Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed: 11481430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[2]	"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. Batut J. Science 293:668-672(2001) [PubMed: 11474104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591688 Genomic DNA. Translation: CAC45932.1.
RefSeq	NP_385459.1. NC_003047.1.
3D structure databases
ProteinModelPortal	Q92QH2.
SMR	Q92QH2. Positions 4-691.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1233005.
GenomeReviews	Gene locus R01353 in contig AL591688_GR.
KEGG	sme:SMc01312.
NMPDR	fig\|266834.1.peg.2647.
PATRIC	23632031. VBISinMel96828_2768.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG737692.
OMA	CNEWREK.
ProtClustDB	PRK00007.
Enzyme and pathway databases
BioCyc	SMEL266834:SMC01312-MONOMER.
Family and domain databases
HAMAP	MF_00054_B. EF-G_EF-2_B. [Tree]
InterPro	IPR009022. Elongation_fac_G/III/V. IPR000795. ProtSyn_GTP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR005225. Small_GTP-bd_dom. IPR004540. Transl_elong_EFG/EF2. IPR000640. Transl_elong_EFG/EF2_C. IPR005517. Transl_elong_EFG/EF2_IV. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Gene3D	G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.30.70.240. Transl_elong_EFG/EF2_C. 1 hit.
KO	K02355.
Pfam	PF00679. EFG_C. 1 hit. PF03764. EFG_IV. 1 hit. PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SMART	SM00838. EFG_C. 1 hit. SM00889. EFG_IV. 1 hit. [Graphical view]
SUPFAM	SSF54980. EFG_III_V. 2 hits. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00484. EF-G. 1 hit. TIGR00231. Small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFG_RHIME

Accession

Primary (citable) accession number: Q92QH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 27, 2002
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents