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Q92Q31 (SYR_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:R01523
ORF Names:SMc02073
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length585 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 585585Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151597

Regions

Motif131 – 14111"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q92Q31 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 9806D9596C3A1CD7

FASTA58564,753
        10         20         30         40         50         60 
MNLFTDFEAR INRILESIEI IREKRSELDF GRINVEPPRD ASHGDVATNA AMVLAKPLGM 

        70         80         90        100        110        120 
NPRALADLIV DKLGQDPEVA GVSVAGPGFI NVRLSVSYWQ KLLAAITRAG VDYGRSTFGA 

       130        140        150        160        170        180 
GRKINVEYVS ANPTGPMHVG HCRGAVVGDA LANLLAFAGY DVTKEYYIND AGSQIEVLAR 

       190        200        210        220        230        240 
SAFLRYRQAL GEDIAEIPAG LYPGDYLVPV GEALADEYGT SLRIMPEDKW VPLVKERVID 

       250        260        270        280        290        300 
AMMAMIREDL AALNVNHDVF FSERALHDNG AARIRTAIND LTFKGHVYKG TLPPPKGQLP 

       310        320        330        340        350        360 
EDWEDREQTL FRSTEVGDDI DRPLIKSDGS YTYFAADVAY FKDKFDRGFH EMIYVLGADH 

       370        380        390        400        410        420 
GGYVKRLEAL ARAISGGTAK LTVLLCQLVK LYRNGEPVKM SKRSGDFVTL RDVVDEVGRD 

       430        440        450        460        470        480 
PVRFMMLYRK SSEPLDFDFA KVTEQSKDNP VFYVQYAHAR CRSVFRQAAE AFPDLDLSSV 

       490        500        510        520        530        540 
DFAAAAGAIV DPTEMQLVAK LAEYPRVVEA AALSHEPHRI AFYLYDLAAV FHGHWNKGKE 

       550        560        570        580 
NPELRFVNDK NRELSIARLG LVHAVASVLK SGLSITGTSA PDEMR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591688 Genomic DNA. Translation: CAC46102.1.
RefSeqNP_385629.1. NC_003047.1.

3D structure databases

ProteinModelPortalQ92Q31.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266834.SMc02073.

Proteomic databases

ProMEXQ92Q31.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC46102; CAC46102; SMc02073.
GeneID1233176.
KEGGsme:SMc02073.
PATRIC23632389. VBISinMel96828_2946.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-1558-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_RHIME
AccessionPrimary (citable) accession number: Q92Q31
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: December 1, 2001
Last modified: April 16, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries