ID   HEM6_RHIME              Reviewed;         303 AA.
AC   Q92PD8;
DT   30-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   16-JUN-2009, entry version 50.
DE   RecName: Full=Coproporphyrinogen-III oxidase, aerobic;
DE            Short=Coproporphyrinogenase;
DE            Short=Coprogen oxidase;
DE            EC=1.3.3.3;
GN   Name=hemF; OrderedLocusNames=R01827; ORFNames=SMc00180;
OS   Rhizobium meliloti (Sinorhizobium meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=382;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   MEDLINE=21396507; PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D.,
RA   Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U.,
RA   Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont
RT   Sinorhizobium meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
CC   -!- CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) =
CC       protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
CC   -!- PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis;
CC       protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step
CC       1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase
CC       family.
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DR   EMBL; AL591688; CAC46406.1; -; Genomic_DNA.
DR   RefSeq; NP_385933.1; -.
DR   GeneID; 1233492; -.
DR   GenomeReviews; AL591688_GR; R01827.
DR   KEGG; sme:SMc00180; -.
DR   NMPDR; fig|266834.1.peg.3121; -.
DR   HOGENOM; Q92PD8; -.
DR   OMA; Q92PD8; VKAYLLD.
DR   BioCyc; SMEL266834:SMC00180-MON; -.
DR   BRENDA; 1.3.3.3; 142.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00333; -; 1.
DR   InterPro; IPR001260; Coprogen_oxidas.
DR   InterPro; IPR018375; Coproporphyrinogen-3_ox_CS.
DR   Gene3D; G3DSA:3.40.1500.10; Coprogen_oxidas; 1.
DR   PANTHER; PTHR10755; Coprogen_oxidas; 1.
DR   Pfam; PF01218; Coprogen_oxidas; 1.
DR   PIRSF; PIRSF000166; Coproporphyri_ox; 1.
DR   PRINTS; PR00073; COPRGNOXDASE.
DR   PROSITE; PS01021; COPROGEN_OXIDASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.
FT   CHAIN         1    303       Coproporphyrinogen-III oxidase, aerobic.
FT                                /FTId=PRO_0000109914.
SQ   SEQUENCE   303 AA;  34322 MW;  8F7715ECD82FAEFA CRC64;
     MERPQLPQGL PADIEDKKAA AKAWFESLRD TICAAFEAIE DELTGPLSDR PAGRFVAKDW
     LREEGAGGGG RMSMMEGRVF EKVGVHTSTV FGEFSPEFRE QIPGASEDPR FWASGISLIA
     HPVNPNVPAV HMNTRMVVTT SNWFGGGADL TPVLDRRRIM TDPDTVLFHR AMEIACNRHP
     VADHAKFKQW CDEYFYLKHR NEPRGTGGIF YDWLRSAEEL GGWDADFAFT RDVGKAFALV
     YPRIVRTNFN KPWTEQDRNE QLVRRGRYVE FNLLYDRGTI FGLKTGGNVE SILSSLPPLV
     RWP
//