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Reviewed, UniProtKB/Swiss-Prot Q92PD8 (HEM6_RHIME)

Last modified June 16, 2009. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: R01827
ORF Names: SMc00180
OrganismRhizobium meliloti (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier382 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

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Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 303303Coproporphyrinogen-III oxidase, aerobic
PRO_0000109914

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Sequences

Sequence LengthMass (Da)Tools
Q92PD8-1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 8F7715ECD82FAEFA

FASTA30334,322
        10         20         30         40         50         60 
MERPQLPQGL PADIEDKKAA AKAWFESLRD TICAAFEAIE DELTGPLSDR PAGRFVAKDW 

        70         80         90        100        110        120 
LREEGAGGGG RMSMMEGRVF EKVGVHTSTV FGEFSPEFRE QIPGASEDPR FWASGISLIA 

       130        140        150        160        170        180 
HPVNPNVPAV HMNTRMVVTT SNWFGGGADL TPVLDRRRIM TDPDTVLFHR AMEIACNRHP 

       190        200        210        220        230        240 
VADHAKFKQW CDEYFYLKHR NEPRGTGGIF YDWLRSAEEL GGWDADFAFT RDVGKAFALV 

       250        260        270        280        290        300 
YPRIVRTNFN KPWTEQDRNE QLVRRGRYVE FNLLYDRGTI FGLKTGGNVE SILSSLPPLV 


RWP

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References

[1]"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021."
Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. expand/collapse author list , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.
Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed: 11481430] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1021.

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Cross-references

Sequence databases

AL591688 Genomic DNA. Translation: CAC46406.1.
RefSeqNP_385933.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1233492.
GenomeReviewsGene locus R01827 in contig AL591688_GR.
KEGGsme:SMc00180.
NMPDRfig|266834.1.peg.3121.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ92PD8.
OMAQ92PD8. VKAYLLD.

Enzyme and pathway databases

BioCycSMEL266834:SMC00180-MON.
BRENDA1.3.3.3. 142.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_RHIME
AccessionPrimary (citable) accession number: Q92PD8
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: December 1, 2001
Last modified: June 16, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents