ID   Q92NW0_RHIME            Unreviewed;       589 AA.
AC   Q92NW0;
DT   01-DEC-2001, integrated into UniProtKB/TrEMBL.
DT   01-DEC-2001, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   SubName: Full=Probable adenylate/guanylate cyclase {ECO:0000313|EMBL:CAC46629.1};
GN   Name=cyaF3 {ECO:0000313|EMBL:CAC46629.1};
GN   ORFNames=SMc04292 {ECO:0000313|EMBL:CAC46629.1};
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834 {ECO:0000313|EMBL:CAC46629.1, ECO:0000313|Proteomes:UP000001976};
RN   [1] {ECO:0000313|EMBL:CAC46629.1, ECO:0000313|Proteomes:UP000001976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021 {ECO:0000313|EMBL:CAC46629.1,
RC   ECO:0000313|Proteomes:UP000001976};
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [2] {ECO:0000313|Proteomes:UP000001976}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021 {ECO:0000313|Proteomes:UP000001976};
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
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DR   EMBL; AL591688; CAC46629.1; -; Genomic_DNA.
DR   RefSeq; NP_386156.1; NC_003047.1.
DR   RefSeq; WP_010969665.1; NC_003047.1.
DR   AlphaFoldDB; Q92NW0; -.
DR   EnsemblBacteria; CAC46629; CAC46629; SMc04292.
DR   GeneID; 61603516; -.
DR   KEGG; sme:SMc04292; -.
DR   PATRIC; fig|266834.11.peg.3504; -.
DR   eggNOG; COG0457; Bacteria.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG5616; Bacteria.
DR   HOGENOM; CLU_019981_0_0_5; -.
DR   OrthoDB; 9807521at2; -.
DR   Proteomes; UP000001976; Chromosome.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.40.50.10070; TolB, N-terminal domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR   Pfam; PF13432; TPR_16; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001976}.
FT   DOMAIN          6..120
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REGION          165..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   589 AA;  64603 MW;  295284848883397E CRC64;
     MRRLAAIMDA DVVGYSRLMG LDEAGTYRAV KRCRDAFILP LVAAHGGRIV KQAGDGTLAE
     FASVLDAVAC AVAIQRTMHD HAGGAEAERL ELRIGVHLGD IVADDGDIHG EGIAVAEHLQ
     EMAPPGGVCV SQQVYDQIGL KVDFPLTEIG CRTFADLPGP LRAWRWQPGG AAGEEPPAPA
     QTDPLPGKKR PSIAVLPFVN LSSVEEQEHF SDGFTEELIA TLARCRWLRV VARNSSFTFK
     GKAADVRRVA EDLGVKYVIE GSIRRAANRI RITAQLLSGE TGMLLWAERY DRMLDDVFVL
     QDEIAGQITG TVEPELGFIE FAALRGHTAT DMDAWNIYLK GLCHLYKFDL ENLRISKALF
     ERAIDLEPAF AQAHARLAYV HIQLGWYGPL DERAERIADA TALAERAIAL DDREPAAHLA
     LGRARALGGQ PQRGIDHLRN ALRLDASFAQ GHFALGQALC YVCRPEEGIA AINEAFRLSP
     RDPHLWTFYN MVAIAHYQSG RFAQAAEAAR ASLRQENATF WPAMVLAASL GATERSDEAG
     SAVANLLRRR PDMTVKTARA EFYFGSVPVM PEDFIDRFVR DLHRAGLPD
//