cyaC

Functionⁱ

GO - Molecular functionⁱ

adenylate cyclase activity Source: UniProtKB-EC
electron carrier activity Source: InterPro
iron-sulfur cluster binding Source: InterPro

Complete GO annotation...

GO - Biological processⁱ

intracellular signal transduction Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	LyaseImported

Molecular function

LyaseImported

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Putative adenylate cyclase transmembrane proteinImported (EC:4.6.1.1Imported)
Gene namesⁱ	Name:cyaCImported ORF Names:SMc01818Imported
Organismⁱ	Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)Imported
Taxonomic identifierⁱ	266834 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Rhizobium meliloti
Proteomesⁱ	UP000001976 Componentⁱ: Chromosome

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	58 – 77	HelicalSequence analysisAdd BLAST	20
Transmembraneⁱ	89 – 107	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	140 – 158	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	170 – 187	HelicalSequence analysisAdd BLAST	18
Transmembraneⁱ	225 – 244	HelicalSequence analysisAdd BLAST	20

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW
intracellular Source: GOC

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	266834.SMc01818.

STRINGⁱ

266834.SMc01818.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q92MZ6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	248 – 343	2Fe-2S ferredoxin-typeInterPro annotationAdd BLAST		96
Domainⁱ	365 – 497	Guanylate cyclaseInterPro annotationAdd BLAST		133

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG4105FCY. Bacteria. COG0633. LUCA.
HOGENOMⁱ	HOG000271405.
KEGG Orthology (KO) More...KOⁱ	K01768.
OMAⁱ	HASVCGG.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00207. fer2. 1 hit.
Gene3Dⁱ	3.10.20.30. 1 hit. 3.30.70.1230. 1 hit.
InterProⁱ	View protein in InterPro IPR001041. 2Fe-2S_ferredoxin-type. IPR001054. A/G_cyclase. IPR012675. Beta-grasp_dom. IPR029787. Nucleotide_cyclase. IPR034804. SQR/QFR_C/D.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00111. Fer2. 1 hit. PF00211. Guanylate_cyc. 1 hit.
SMARTⁱ	View protein in SMART SM00044. CYCc. 1 hit.
SUPFAMⁱ	SSF54292. SSF54292. 1 hit. SSF55073. SSF55073. 1 hit. SSF81343. SSF81343. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51085. 2FE2S_FER_2. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q92MZ6-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTILSASTRK KMHLISGAVL GVFVLLHFSN HALGLVSIDA METGRRIFTS 
        60         70         80         90        100
VWQSIPGTAL LYGALLLHFL MALDSLYRRQ TFRMPVGEAL KIIFGLSLPF 
       110        120        130        140        150
LLVPHVVAAR VEPLLSGVYP DYPAILRTLW SSSFNTSRQS LALIVVWGHA 
       160        170        180        190        200
CLGAWFWMRG RAWFPKYETL LYTVALLVPI FALLGFVNGA RSLERDYAEH 
       210        220        230        240        250
GGYGDRAYSS QAPRVDPNLL DKIRLAFYGG FASLIGGTLV LRALPARGRI 
       260        270        280        290        300
RIRYPDGRVA AVSLGFSVLE ASRAAGIPHV SVCGGRGRCS TCRVRITQGL 
       310        320        330        340        350
EGQPPPEAAE LATLTRIGAP ENVRLACQFR PVHNVSVVPI LDTDSLGIKT 
       360        370        380        390        400
QLARQNAGGR ERRVAVLFCD LRDFTRIAEH RLPYDTVFLL NRYFEVVGEA 
       410        420        430        440        450
VEGSGGVVDK FIGDGALAIF GLKTPLPEAC RQALSAAARL SQGIRALNQT 
       460        470        480        490        500
FEGELEQPLR LAIGLHAGPA IIGEMGYGQA TSLTVVGDTI NTASRLEGLA 
       510        520        530        540        550
KEHDVELAVS AELVERAGLS FEGHRRLEIG LRGRKATLET WIIGDAAQLS 

LSLPMQG

Length:557

Mass (Da):60,512

Last modified:December 1, 2001 - v1

Checksum:ⁱ9F709A612C702B3D

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL591688 Genomic DNA. Translation: CAC47030.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_386557.1. NC_003047.1. WP_010969945.1. NC_003047.1.

Genome annotation databases

EnsemblBacteriaⁱ	CAC47030; CAC47030; SMc01818.
GeneIDⁱ	1234118.
KEGGⁱ	sme:SMc01818.
PATRICⁱ	fig\|266834.11.peg.3939.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL591688 Genomic DNA. Translation: CAC47030.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_386557.1. NC_003047.1. WP_010969945.1. NC_003047.1.

3D structure databases

ProteinModelPortalⁱ	Q92MZ6.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	266834.SMc01818.

STRINGⁱ

266834.SMc01818.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	CAC47030; CAC47030; SMc01818.
GeneIDⁱ	1234118.
KEGGⁱ	sme:SMc01818.
PATRICⁱ	fig\|266834.11.peg.3939.

Phylogenomic databases

eggNOGⁱ	ENOG4105FCY. Bacteria. COG0633. LUCA.
HOGENOMⁱ	HOG000271405.
KEGG Orthology (KO) More...KOⁱ	K01768.
OMAⁱ	HASVCGG.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00207. fer2. 1 hit.
Gene3Dⁱ	3.10.20.30. 1 hit. 3.30.70.1230. 1 hit.
InterProⁱ	View protein in InterPro IPR001041. 2Fe-2S_ferredoxin-type. IPR001054. A/G_cyclase. IPR012675. Beta-grasp_dom. IPR029787. Nucleotide_cyclase. IPR034804. SQR/QFR_C/D.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00111. Fer2. 1 hit. PF00211. Guanylate_cyc. 1 hit.
SMARTⁱ	View protein in SMART SM00044. CYCc. 1 hit.
SUPFAMⁱ	SSF54292. SSF54292. 1 hit. SSF55073. SSF55073. 1 hit. SSF81343. SSF81343. 1 hit.
PROSITEⁱ	View protein in PROSITE PS51085. 2FE2S_FER_2. 1 hit. PS50125. GUANYLATE_CYCLASE_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q92MZ6_RHIME
Accessionⁱ	Q92MZ6Primary (citable) accession number: Q92MZ6
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 1, 2001
	Last sequence update:	December 1, 2001
	Last modified:	June 7, 2017
	This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB - Q92MZ6 (Q92MZ6_RHIME)

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Putative adenylate cyclase transmembrane protein

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q92MZ6 (Q92MZ6_RHIME)

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Putative adenylate cyclase transmembrane protein

cyaC

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ