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Q92MQ8

- G6PI1_RHIME

UniProt

Q92MQ8 - G6PI1_RHIME

Protein

Putative glucose-6-phosphate isomerase 1

Gene

pgiA1

Organism
Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.

    Cofactori

    Binds 1 iron ion per subunit.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi92 – 921IronBy similarity
    Metal bindingi94 – 941IronBy similarity
    Metal bindingi101 – 1011IronBy similarity
    Metal bindingi140 – 1401IronBy similarity

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
    2. iron ion binding Source: InterPro

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Keywords - Ligandi

    Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciSMEL266834:GJF6-2611-MONOMER.
    SABIO-RKQ92MQ8.
    UniPathwayiUPA00109; UER00181.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative glucose-6-phosphate isomerase 1 (EC:5.3.1.9)
    Short name:
    GPI 1
    Alternative name(s):
    Phosphoglucose isomerase 1
    Short name:
    PGI 1
    Phosphohexose isomerase 1
    Short name:
    PHI 1
    Gene namesi
    Name:pgiA1
    Ordered Locus Names:R02554
    ORF Names:SMc02042
    OrganismiRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
    Taxonomic identifieri266834 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
    ProteomesiUP000001976: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 214214Putative glucose-6-phosphate isomerase 1PRO_0000185361Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Protein-protein interaction databases

    STRINGi266834.SMc02042.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92MQ8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the archaeal-type GPI family.Curated

    Phylogenomic databases

    eggNOGiCOG2140.
    HOGENOMiHOG000243903.
    KOiK06859.
    OMAiYPADAGH.
    OrthoDBiEOG6M6JRR.

    Family and domain databases

    Gene3Di2.60.120.10. 1 hit.
    HAMAPiMF_01410. G6P_isomerase_arch.
    InterProiIPR010551. G6P_isomerase_prok.
    IPR016758. G6P_isomerase_subgr.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view]
    PfamiPF06560. GPI. 1 hit.
    [Graphical view]
    PIRSFiPIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
    SUPFAMiSSF51182. SSF51182. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q92MQ8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKLFEPAGC RVDLRTGAMS DATGAYQKRF RDLAGLYADE AAFSAMQETW    50
    NDTVVYEVSE FRPNERTGDL IFGVTRMLPG KVGEEYFVTR GHIHKQSDRP 100
    EIYYGQKGRG LMLLESPEGE VRVVAVDAQT VCYVPPYWIH RSVNIGGDEL 150
    VMLFCYPADS GQDYDCIAKA GGMRARIIDD GRGGWKQIDN PNWRMRDAAT 200
    VAALYGREKK EENA 214
    Length:214
    Mass (Da):24,049
    Last modified:December 1, 2001 - v1
    Checksum:i062127EC48458BBF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL591688 Genomic DNA. Translation: CAC47133.1.
    RefSeqiNP_386660.1. NC_003047.1.

    Genome annotation databases

    EnsemblBacteriaiCAC47133; CAC47133; SMc02042.
    GeneIDi1234222.
    KEGGisme:SMc02042.
    PATRICi23634625. VBISinMel96828_4050.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL591688 Genomic DNA. Translation: CAC47133.1 .
    RefSeqi NP_386660.1. NC_003047.1.

    3D structure databases

    ProteinModelPortali Q92MQ8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 266834.SMc02042.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC47133 ; CAC47133 ; SMc02042 .
    GeneIDi 1234222.
    KEGGi sme:SMc02042.
    PATRICi 23634625. VBISinMel96828_4050.

    Phylogenomic databases

    eggNOGi COG2140.
    HOGENOMi HOG000243903.
    KOi K06859.
    OMAi YPADAGH.
    OrthoDBi EOG6M6JRR.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    BioCyci SMEL266834:GJF6-2611-MONOMER.
    SABIO-RK Q92MQ8.

    Family and domain databases

    Gene3Di 2.60.120.10. 1 hit.
    HAMAPi MF_01410. G6P_isomerase_arch.
    InterProi IPR010551. G6P_isomerase_prok.
    IPR016758. G6P_isomerase_subgr.
    IPR014710. RmlC-like_jellyroll.
    IPR011051. RmlC_Cupin.
    [Graphical view ]
    Pfami PF06560. GPI. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
    SUPFAMi SSF51182. SSF51182. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1021.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 1021.

    Entry informationi

    Entry nameiG6PI1_RHIME
    AccessioniPrimary (citable) accession number: Q92MQ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    R.meliloti has a classic glucose-6-phosphate isomerase (AC Q92SC4) and two archaeal-type glucose-6-phosphate isomerases.

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3