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Q92MQ8 (G6PI1_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative glucose-6-phosphate isomerase 1

Short name=GPI 1
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase 1
Short name=PGI 1
Phosphohexose isomerase 1
Short name=PHI 1
Gene names
Name:pgiA1
Ordered Locus Names:R02554
ORF Names:SMc02042
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_01410

Cofactor

Binds 1 iron ion per subunit By similarity. HAMAP-Rule MF_01410

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_01410

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01410

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01410.

Miscellaneous

R.meliloti has a classic glucose-6-phosphate isomerase (AC Q92SC4) and two archaeal-type glucose-6-phosphate isomerases.

Sequence similarities

Belongs to the archaeal-type GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   LigandIron
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

iron ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 214214Putative glucose-6-phosphate isomerase 1 HAMAP-Rule MF_01410
PRO_0000185361

Sites

Metal binding921Iron By similarity
Metal binding941Iron By similarity
Metal binding1011Iron By similarity
Metal binding1401Iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92MQ8 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 062127EC48458BBF

FASTA21424,049
        10         20         30         40         50         60 
MTKLFEPAGC RVDLRTGAMS DATGAYQKRF RDLAGLYADE AAFSAMQETW NDTVVYEVSE 

        70         80         90        100        110        120 
FRPNERTGDL IFGVTRMLPG KVGEEYFVTR GHIHKQSDRP EIYYGQKGRG LMLLESPEGE 

       130        140        150        160        170        180 
VRVVAVDAQT VCYVPPYWIH RSVNIGGDEL VMLFCYPADS GQDYDCIAKA GGMRARIIDD 

       190        200        210 
GRGGWKQIDN PNWRMRDAAT VAALYGREKK EENA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591688 Genomic DNA. Translation: CAC47133.1.
RefSeqNP_386660.1. NC_003047.1.

3D structure databases

ProteinModelPortalQ92MQ8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING266834.SMc02042.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC47133; CAC47133; SMc02042.
GeneID1234222.
KEGGsme:SMc02042.
PATRIC23634625. VBISinMel96828_4050.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2140.
HOGENOMHOG000243903.
KOK06859.
OMAYPADAGH.
OrthoDBEOG6M6JRR.
ProtClustDBPRK04190.

Enzyme and pathway databases

BioCycSMEL266834:GJF6-2611-MONOMER.
SABIO-RKQ92MQ8.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D2.60.120.10. 1 hit.
HAMAPMF_01410. G6P_isomerase_arch.
InterProIPR010551. G6P_isomerase_prok.
IPR016758. G6P_isomerase_subgr.
IPR014710. RmlC-like_jellyroll.
IPR011051. RmlC_Cupin.
[Graphical view]
PfamPF06560. GPI. 1 hit.
[Graphical view]
PIRSFPIRSF019325. Glucose-6-phosphate_isomerase. 1 hit.
SUPFAMSSF51182. SSF51182. 1 hit.
ProtoNetSearch...

Entry information

Entry nameG6PI1_RHIME
AccessionPrimary (citable) accession number: Q92MQ8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways