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Q92MG0 (HIS81_RHIME) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase 1

EC=2.6.1.9
Alternative name(s):
Imidazole acetol-phosphate transaminase 1
Gene names
Name:hisC1
Ordered Locus Names:R02662
ORF Names:SMc00710
OrganismRhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]
Taxonomic identifier266834 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 368368Histidinol-phosphate aminotransferase 1 HAMAP MF_01023
PRO_0000153435

Amino acid modifications

Modified residue2241N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q92MG0 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 3168EF45EF7D8046

FASTA36839,171
        10         20         30         40         50         60 
MNLALKSPAP RSGILDIAAY VPGKEHAPGV AKVHKLSSNE TPLGASPRAI EAFQKAAFNL 

        70         80         90        100        110        120 
ERYPDGQANA LKEAIAAVHG LNPANILCGN GSDELLGLLC HTYLGPGDEG IVTEHGFLVY 

       130        140        150        160        170        180 
KIQITASGGT PVTVKERQER VDVDAILAAV TERTKIVFIA NPANPTGTYI PVEEVRRLHA 

       190        200        210        220        230        240 
GLPAGVLLVL DAAYAEYVRR NDYEAGLELV SSNRNVVMTR TFSKIYGLAG LRIGWMYAPR 

       250        260        270        280        290        300 
DVVEALDRVR GPFNLNAAAI AAGAAAIRDQ AFVAAAVDQN HTWLAKIGQA LTDIGLRVTP 

       310        320        330        340        350        360 
SVTNFVLIHF PEEAGMSASD ADAYLTSRGF ILRAVGAYGF PNALRMTIGS EEANKGVVAA 


LTEFMGRK 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL591688 Genomic DNA. Translation: CAC47241.1.
RefSeqNP_386768.1. NC_003047.1.

3D structure databases

ProteinModelPortalQ92MG0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1234337.
GenomeReviewsGene locus R02662 in contig AL591688_GR.
KEGGsme:SMc00710.
NMPDRfig|266834.1.peg.3956.
PATRIC23634861. VBISinMel96828_4162.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646350.
OMAGFLVYRI.
ProtClustDBPRK02731.

Enzyme and pathway databases

BioCycSMEL266834:SMC00710-MONOMER.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001176. ACC_synthase.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00753. ACCSYNTHASE.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHIS81_RHIME
AccessionPrimary (citable) accession number: Q92MG0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families