Q92M71 (SUHB_RHIME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Inositol-1-monophosphatase
Short name=I-1-Pase
Short name=IMPase
Short name=Inositol-1-phosphatase
EC=3.1.3.25

Gene names

Name:	suhB
Ordered Locus Names:	R02778
ORF Names:	SMc03994

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Myo-inositol phosphate + H2O = myo-inositol + phosphate.
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the inositol monophosphatase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	inositol monophosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 266	266	Inositol-1-monophosphatase		PRO_0000142571
Regions
	Region	88 – 91	4	Substrate binding By similarity
Sites
	Metal binding	69	1	Magnesium 1 By similarity
	Metal binding	86	1	Magnesium 1 By similarity
	Metal binding	86	1	Magnesium 2 By similarity
	Metal binding	88	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	89	1	Magnesium 2 By similarity
	Metal binding	214	1	Magnesium 2 By similarity
	Binding site	69	1	Substrate By similarity
	Binding site	185	1	Substrate By similarity
	Binding site	214	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q92M71 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 542590D938397BC7	FASTA	266	28,685
	10 20 30 40 50 60 MARSALLNVM VQAVFKAGKS LARDFGEVQN LQVSLKGPAD YVSQADRKAE RIIREELMKA 70 80 90 100 110 120 RPTYGFLGEE GEEIKGTDGA HRWIVDPLDG TTNFLHGIPH FAISVALERQ GEIVGAVVFN 130 140 150 160 170 180 PATDELYTAE RGGGAFLNDR RLRVGARKAL SDAVIGTGTP HLGRGNHGKY LVELRHVMGE 190 200 210 220 230 240 VAGIRRMGSA SLDLAYVAAG RFDGFWERDL AAWDMAAGLL LIREAGGWST DAEGGGKPLE 250 260 AGSIVCGNEH IAKALREVIQ RPIPSK

References

[1]	"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021." Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F. Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed: 11481430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[2]	"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J. Science 293:668-672(2001) [PubMed: 11474104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL591688 Genomic DNA. Translation: CAC47357.1.
RefSeq	NP_386884.1. NC_003047.1.
3D structure databases
ProteinModelPortal	Q92M71.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1234454.
GenomeReviews	Gene locus R02778 in contig AL591688_GR.
KEGG	sme:SMc03994.
NMPDR	fig|266834.1.peg.4072.
PATRIC	23635119. VBISinMel96828_4290.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG730251.
OMA	PATWYID.
ProtClustDB	CLSK800938.
Enzyme and pathway databases
BioCyc	SMEL266834:SMC03994-MONOMER.
Family and domain databases
InterPro	IPR020583. Inositol_monoP_metal-BS. IPR000760. Inositol_monophosphatase. IPR020550. Inositol_monophosphatase_CS. IPR022337. Inositol_monophosphatase_SuhB. [Graphical view]
KO	K01092.
PANTHER	PTHR20854. Inositol_P. 1 hit.
Pfam	PF00459. Inositol_P. 1 hit. [Graphical view]
PRINTS	PR00377. IMPHPHTASES. PR01959. SBIMPHPHTASE.
PROSITE	PS00629. IMP_1. 1 hit. PS00630. IMP_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SUHB_RHIME

Accession

Primary (citable) accession number: Q92M71

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 23, 2002
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program